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Socio-Economic Objective : Sugar
Field of Research : Molecular Evolution
Australian State/Territory : NSW
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    Linkage Projects - Grant ID: LP0453776

    Funder
    Australian Research Council
    Funding Amount
    $240,000.00
    Summary
    In vitro evolution of more thermostable dextranases for the Australian sugar industry. Dextrans are polysaccharides that adversely affect the productivity of sugarcane mills. The Australian sugar industry currently imports dextranases to deal with this problem but they are not heat stable so the mills have run at lower temperatures than optimal. We have isolated dextranases from thermophilic microorganisms and aim to improve their performance by generating superior heat-stable dextranases using .... In vitro evolution of more thermostable dextranases for the Australian sugar industry. Dextrans are polysaccharides that adversely affect the productivity of sugarcane mills. The Australian sugar industry currently imports dextranases to deal with this problem but they are not heat stable so the mills have run at lower temperatures than optimal. We have isolated dextranases from thermophilic microorganisms and aim to improve their performance by generating superior heat-stable dextranases using in vitro evolution, creating new activity levels by random mutation and recombination. The research will be significant in providing novel enzymes for domestic use, allowing import substitution and an outcome will be the development of a product with export potential.
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