Dynamic social systems and adolescent alcohol/tobacco use: A new cusp catastrophe model. This research will substantially improve our understanding of the development of adolescent high-risk behaviours. It will directly inform multimodal prevention strategies by demonstrating how substance use, peer factors, and parent relationships unfold over time. This is much needed because most prevention strategies are too simplistic to address complex precursors to alcohol/tobacco use. The research wil ....Dynamic social systems and adolescent alcohol/tobacco use: A new cusp catastrophe model. This research will substantially improve our understanding of the development of adolescent high-risk behaviours. It will directly inform multimodal prevention strategies by demonstrating how substance use, peer factors, and parent relationships unfold over time. This is much needed because most prevention strategies are too simplistic to address complex precursors to alcohol/tobacco use. The research will benefit health researchers in and beyond Australia who seek to understand behaviours that do not adhere to conventional assumptions. Collaboration with researchers from leading national and international centres will enhance Australia's research reputation and will attract postgraduates and researchers to Australia.Read moreRead less
The initiation, development, and maintenance of alcohol/tobacco use in adolescents: The role of associative memory. Alcohol abuse and tobacco misuse are common in Australian adolescents and its long-term health consequences are well established. Models of drug-related memory association predict drug use in adults. However, memory association models have not been applied to smoking behaviour, or to understanding adolescent alcohol/tobacco use over time. It is expected that memory associations ....The initiation, development, and maintenance of alcohol/tobacco use in adolescents: The role of associative memory. Alcohol abuse and tobacco misuse are common in Australian adolescents and its long-term health consequences are well established. Models of drug-related memory association predict drug use in adults. However, memory association models have not been applied to smoking behaviour, or to understanding adolescent alcohol/tobacco use over time. It is expected that memory associations will predict the development of alcohol/tobacco use and misuse, after accounting for viable alternative explanations of the association. Understanding the role that memory associations have in the development of alcohol/tobacco use should inform prevention programs for at-risk adolescents.Read moreRead less
Drug Use by a Community Sample of Young Amphetamine Users in South-East Queensland â?' A Longitudinal Study. Drug use can impact on the national well being in a multitude of ways. In 1998-1999 the fiscal cost of licit and illicit drug use was estimated to be $34.4 billion, while drug-related crime is estimated to cost Australia $1.96 billion annually. This study is valuable in its capacity to inform evidence-based policy and practice addressing amphetamine uptake and amphetamine use trajectories ....Drug Use by a Community Sample of Young Amphetamine Users in South-East Queensland â?' A Longitudinal Study. Drug use can impact on the national well being in a multitude of ways. In 1998-1999 the fiscal cost of licit and illicit drug use was estimated to be $34.4 billion, while drug-related crime is estimated to cost Australia $1.96 billion annually. This study is valuable in its capacity to inform evidence-based policy and practice addressing amphetamine uptake and amphetamine use trajectories and harms. This has implications for developing strategies to enable young Australians to make healthy choices regarding amphetamine and other drug use, and for the broader economic and social benefits arising from healthy and productive individuals, families and communities.Read moreRead less
Addiction, moral identity and moral agency: Integrating theoretical and empirical approaches. By clarifying and evaluating scientific claims about the moral impacts of addiction on the judgment and practices of drug addicted persons and by investigating the perspectives of users and treatment professionals, our project will contribute to the development of ethical and effective public policy, treatment and education programs in the addictions area, thus helping to address the causes and reduce t ....Addiction, moral identity and moral agency: Integrating theoretical and empirical approaches. By clarifying and evaluating scientific claims about the moral impacts of addiction on the judgment and practices of drug addicted persons and by investigating the perspectives of users and treatment professionals, our project will contribute to the development of ethical and effective public policy, treatment and education programs in the addictions area, thus helping to address the causes and reduce the impact of biological, social and environmental factors which diminish life potential in drug addicted persons. The innovative features of this project will enhance Australia's international reputation in bioethics and moral psychology, extend the reach of experimental philosophy, and facilitate future interdisciplinary work.Read moreRead less
Drosophila Quantitative Genomics. This research proposal will be a key element in the emerging program in evolutionary and ecological functional genomics at the University of Queensland. Our studies utilize modern genomics approaches to address diverse national priorities from conservation of biological resources in the face of climate change, to understanding how genetic history contributes to drug susceptibility. The research will contribute to the intellectual foundation upon which rigorous ....Drosophila Quantitative Genomics. This research proposal will be a key element in the emerging program in evolutionary and ecological functional genomics at the University of Queensland. Our studies utilize modern genomics approaches to address diverse national priorities from conservation of biological resources in the face of climate change, to understanding how genetic history contributes to drug susceptibility. The research will contribute to the intellectual foundation upon which rigorous environmental and biomedical research is built. Social impact will be seen in the training of a new generation of integrative genome biologists, and the shaping of attitudes toward the role of genetics in human biology.Read moreRead less
The influence of parental alcohol expectancies on offsprings' alcohol expectancies and drinking: A longitudinal study. It has been shown that potentially modifiable alcohol related cognitions, such as alcohol expectancies (AE)and drinking refusal self-efficacy (DRSE) are formed in childhood are related to drinking in adolescents and adults. The question of how these beliefs are formed is still unanswered. This longitudinal study examines the influences of parental alcohol-related beliefs and ....The influence of parental alcohol expectancies on offsprings' alcohol expectancies and drinking: A longitudinal study. It has been shown that potentially modifiable alcohol related cognitions, such as alcohol expectancies (AE)and drinking refusal self-efficacy (DRSE) are formed in childhood are related to drinking in adolescents and adults. The question of how these beliefs are formed is still unanswered. This longitudinal study examines the influences of parental alcohol-related beliefs and drinking, on children's alcohol-related beliefs and drinking behaviour. Positive results of this study will improve primary prevention by identifying and changing modifiable variables for populations potentially at-risk of developing later alcohol-related. It will also help to reduce cost and suffering of a major problem in Ausstralia.
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Evaluation of treatment outcomes for court-referred and voluntary clients in residential and outclient substance abuse treatment programs. Very little research has been conducted evaluating the relative effectiveness of substance abuse treatment programs for court-referred clients, compared with voluntary clients. This project will obtain psychological, social and health measures in order to compare short- and long-term treatment outcomes. Its significance lies not only in its potential to evalu ....Evaluation of treatment outcomes for court-referred and voluntary clients in residential and outclient substance abuse treatment programs. Very little research has been conducted evaluating the relative effectiveness of substance abuse treatment programs for court-referred clients, compared with voluntary clients. This project will obtain psychological, social and health measures in order to compare short- and long-term treatment outcomes. Its significance lies not only in its potential to evaluate the success of treatment for clients diverted from the criminal justice system, but also in its unique focus on a wide range of outcomes for different client groups.Read moreRead less
Determinants of Expression, Assembly and Function of the Noradrenaline Transporter. The noradrenaline transporter protein that is the focus of this project is important for mental health because it belongs to the family of proteins where psychostimulants, such as cocaine, and drugs used in the treatment of depression act. The project will lead to exciting advances in our understanding of how the structure of this protein controls its functions, and potentially to the design of better antidepress ....Determinants of Expression, Assembly and Function of the Noradrenaline Transporter. The noradrenaline transporter protein that is the focus of this project is important for mental health because it belongs to the family of proteins where psychostimulants, such as cocaine, and drugs used in the treatment of depression act. The project will lead to exciting advances in our understanding of how the structure of this protein controls its functions, and potentially to the design of better antidepressant drugs and to the design of drugs to prevent the effects of cocaine.Read moreRead less
The impact of illicit drug users on family members and non-using siblings. This research is a continuation and expansion of the pilot study conducted in 2001 that focussed on the effect on siblings of illicit drug use by a family member from the Vietnamese community. This research will include other ethnic groups and seek to discover the availability of and demand for drug and family support services for non-using family members. Additionally, the research will draw on the knowledge of drug an ....The impact of illicit drug users on family members and non-using siblings. This research is a continuation and expansion of the pilot study conducted in 2001 that focussed on the effect on siblings of illicit drug use by a family member from the Vietnamese community. This research will include other ethnic groups and seek to discover the availability of and demand for drug and family support services for non-using family members. Additionally, the research will draw on the knowledge of drug and family workers, in order to develop guidelines on how they can improve services for young people who have a sibling with an illicit drug addiction.Read moreRead less