Iron, ferroptosis and the biology of ageing. This project aims to determine how and when regulation of iron is lost. Failing iron metabolism during life may dictate the rate of ageing by driving a newly discovered cell death program. Combining biology, chemistry and physics, this collaborative project aims to transform the understanding of the fundamental mechanisms of biological ageing. Anticipated outcomes include new assays for measuring iron in biology and identification of potential pathway ....Iron, ferroptosis and the biology of ageing. This project aims to determine how and when regulation of iron is lost. Failing iron metabolism during life may dictate the rate of ageing by driving a newly discovered cell death program. Combining biology, chemistry and physics, this collaborative project aims to transform the understanding of the fundamental mechanisms of biological ageing. Anticipated outcomes include new assays for measuring iron in biology and identification of potential pathways that regulate death signaling and lifespan. Outcomes will benefit life sciences and biotechnology industries.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120102906
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Topology optimisation for advanced engineered nanostructures. Advanced technological innovation requires extraordinary material properties, which can be generated directly from engineered nanostructures by manipulating surface plasmon resonances. The project will develop a new computational method for nanostructural design and expect to benefit aerospace, biomedical, optical and energy engineering fields.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100090
Funder
Australian Research Council
Funding Amount
$1,136,244.00
Summary
Xe-plasma dual beam for advanced future materials. This project aims to establish a state of the art Xe-Plasma dual-beam facility providing characterisation and fabrication capabilities to Australia’s research community. The project will use two beams - one Xe, the other electrons - to mill the surface of bulk materials which are subsequently analysed by electron or ion beam techniques to determine atomic-scale microstructure(s) and compositions. Anticipated outcomes are advanced materials engin ....Xe-plasma dual beam for advanced future materials. This project aims to establish a state of the art Xe-Plasma dual-beam facility providing characterisation and fabrication capabilities to Australia’s research community. The project will use two beams - one Xe, the other electrons - to mill the surface of bulk materials which are subsequently analysed by electron or ion beam techniques to determine atomic-scale microstructure(s) and compositions. Anticipated outcomes are advanced materials engineering and new knowledge about ancient and future materials. This is expected to provide significant advances across a variety of fields including material science, engineering and geology and enhance trans-disciplinary collaborations.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100030
Funder
Australian Research Council
Funding Amount
$541,705.00
Summary
National facility for nanoscale characterisation of luminescent materials. The project aims to establish a national facility for nanoscale characterisation of advanced optoelectronic materials, including atomically-thin materials, luminescent nanocrystals, metamaterials, and plasmonic nanostructures. The combination of a highly focused electron beam, and novel light detection optics, will enable temperature-dependent, angle, polarisation and time-resolved luminescence analysis with unprecedented ....National facility for nanoscale characterisation of luminescent materials. The project aims to establish a national facility for nanoscale characterisation of advanced optoelectronic materials, including atomically-thin materials, luminescent nanocrystals, metamaterials, and plasmonic nanostructures. The combination of a highly focused electron beam, and novel light detection optics, will enable temperature-dependent, angle, polarisation and time-resolved luminescence analysis with unprecedented resolution. It is expected this will yield discoveries in nanoscale physics and materials science. It will create interdisciplinary collaborations by linking Australian scientists who use high-resolution multimodal characterisation methods to innovate and develop materials and device technologies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100179
Funder
Australian Research Council
Funding Amount
$3,189,000.00
Summary
Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology. This project aims to establish a facility in automated, single-particle cryo-TEM and cryo-TEM tomography (Titan Krios) that will enable atomic and molecular structure research and three-dimensional subcellular and cellular imaging. The project will span all multiscale cryo-TEM modalities from the visualisation of cells, membranes and macromolecular complexes, through to near-atomic-resolution protein ....Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology. This project aims to establish a facility in automated, single-particle cryo-TEM and cryo-TEM tomography (Titan Krios) that will enable atomic and molecular structure research and three-dimensional subcellular and cellular imaging. The project will span all multiscale cryo-TEM modalities from the visualisation of cells, membranes and macromolecular complexes, through to near-atomic-resolution protein structure determination. Cryo-single particle analysis and tomography are recognised as revolutionary technologies in molecular structural biology and powerful enablers of future ground-breaking discovery. The project will deliver significant competitive advantage for Australia in leading-edge structure-based research, drug discovery, new opportunities for applied research and development, and showcasing science to the public.Read moreRead less
Integration of DNA switches into wearables for smart chemical monitoring. This project addresses the scientific challenge of real-time monitoring of dynamic biological changes in the secretions found in sweat. By creating a wearable wireless device to monitor chemicals which interests Nutromics, using a novel electronic skin technology platform, the work aims to generate new knowledge of physiological changes in sweat secretions. Lying at the interface of analytical chemistry, functional materia ....Integration of DNA switches into wearables for smart chemical monitoring. This project addresses the scientific challenge of real-time monitoring of dynamic biological changes in the secretions found in sweat. By creating a wearable wireless device to monitor chemicals which interests Nutromics, using a novel electronic skin technology platform, the work aims to generate new knowledge of physiological changes in sweat secretions. Lying at the interface of analytical chemistry, functional materials and biomedical engineering, the project will contribute to the training of young researchers in these emerging technologies which interest Nutromics Pty Ltd. The project will improve Australia's standing in technology around wearable devices, improving our global competitive edge with economic and scientific impact.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100203
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
Ultrafast optoelectronic characterisation for optical and wireless systems. Ultra-fast optoelectronic characterisation for optical and wireless systems:
The project aims to establish an ultra-fast optoelectronic characterisation facility to measure a wide range of electronic and photonic signals, providing versatile tools for conducting research on ultra-high-speed optical communications, microwave photonics, and millimetre wave systems. There is an increasing need for parallel signalling using ....Ultrafast optoelectronic characterisation for optical and wireless systems. Ultra-fast optoelectronic characterisation for optical and wireless systems:
The project aims to establish an ultra-fast optoelectronic characterisation facility to measure a wide range of electronic and photonic signals, providing versatile tools for conducting research on ultra-high-speed optical communications, microwave photonics, and millimetre wave systems. There is an increasing need for parallel signalling using spatial, temporal and spectral degrees of freedom in both radio-frequency and optical communications. The facility expects to leverage the recent rapid advances in powerful silicon digital signal processors with unprecedented capabilities in bandwidth and accuracy and focus on detecting massively parallel signals. The project aims to support a wide range of research activities from sustaining the phenomenal Internet growth in telecommunications to strengthening Australia’s defence systems.Read moreRead less
ARC Centre of Excellence in Advanced Molecular Imaging. The Centre of Excellence in Advanced Molecular Imaging will innovatively integrate physics, chemistry and biology to unravel the complex molecular interactions that define immunity. The Centre will develop new imaging methods to visualize atomic, molecular and cellular details of how immune proteins interact and
effect immune responses. Outcomes: (i) new technological innovations leading to new imaging methods and products; and (ii) fundame ....ARC Centre of Excellence in Advanced Molecular Imaging. The Centre of Excellence in Advanced Molecular Imaging will innovatively integrate physics, chemistry and biology to unravel the complex molecular interactions that define immunity. The Centre will develop new imaging methods to visualize atomic, molecular and cellular details of how immune proteins interact and
effect immune responses. Outcomes: (i) new technological innovations leading to new imaging methods and products; and (ii) fundamental advances in understanding details of immune responses in health and disease. The Centre will enable Australia to be an international leader in biological imaging, to train next
generation interdisciplinary scientists, and to provide new insights for combating common diseases that afflict society.Read moreRead less
ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to unde ....ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to understand how single cells react to and communicate with their surroundings. This science will underpin a new generation of devices capable of probing the response of cells within individuals to environmental conditions or treatment, creating innovative and powerful new sensing platforms.Read moreRead less
ARC Centre of Excellence for Ultrahigh Bandwidth Devices for Optical Systems. The Centre will take the next big step in optical systems by transforming photonic integrated circuits into a technology that will have a profound effect on economies and lifestyles around the world. This will enable the Internet to transfer vast amounts of data with significantly improved energy efficiency; it will lead to secure transmission using quantum photonics-based devices, and to the detection of mid-infrared ....ARC Centre of Excellence for Ultrahigh Bandwidth Devices for Optical Systems. The Centre will take the next big step in optical systems by transforming photonic integrated circuits into a technology that will have a profound effect on economies and lifestyles around the world. This will enable the Internet to transfer vast amounts of data with significantly improved energy efficiency; it will lead to secure transmission using quantum photonics-based devices, and to the detection of mid-infrared signatures of light from distant stars and complex molecules of environmental or biochemical importance. We will achieve this by developing new materials with optical properties to control light and engineering them into miniature photonic processors.Read moreRead less