Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most importa ....Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches. Understanding how cells can sense and respond to mechanical environment such as dynamic blood flow represents a fundamental question in the emerging field of mechanobiology. This project develops new biomechanical engineering approaches to determine the critical interrelationships among fluid flow disturbance, platelet clotting and the mechano-sensitive signal transduction mechanisms of integrin receptor – the most important mechano-sensor implicated in cell adhesion, migration, growth and survival. Specifically, it integrates nationally unique cutting-edge techniques including single-molecule force probe, microparticle image velocimetry, microfluidics and molecular dynamics simulation, super resolution and 3D volumetric imaging modalities.Read moreRead less
Atomic sensors for dark matter, rotation and magnetic fields. This project aims to develop ultra-high-performance sensors. The research will explore new methods for using the magnetic and optical properties of atomic gases to enable multi-parameter sensing without crosstalk between measurements. It is expected that techniques will be developed to allow simultaneous sensing of rotation and magnetic fields using devices that are compact, ultra-precise and energy efficient. It is also anticipated t ....Atomic sensors for dark matter, rotation and magnetic fields. This project aims to develop ultra-high-performance sensors. The research will explore new methods for using the magnetic and optical properties of atomic gases to enable multi-parameter sensing without crosstalk between measurements. It is expected that techniques will be developed to allow simultaneous sensing of rotation and magnetic fields using devices that are compact, ultra-precise and energy efficient. It is also anticipated that these new atomic sensors will support a global network looking for dark matter, which although never seen, is thought to make up 85% of the mass of the universe. The outcomes are expected to benefit medical science, geo-exploration, high-tech manufacturing, navigation and our understanding of the universe.Read moreRead less
Resonator-enhanced quantum levitation of macroscopic systems. This project aims to develop advanced technologies to optically levitate macroscopic (millimetre-sized) objects and nanoscopic (atomically thin) materials. Levitation platforms built by the investigatory team are based on the resonantly amplified radiation pressure of laser beams. This new type of optical levitation can provide ultimate isolation of the systems from external noise, making them extremely responsive to subtle environmen ....Resonator-enhanced quantum levitation of macroscopic systems. This project aims to develop advanced technologies to optically levitate macroscopic (millimetre-sized) objects and nanoscopic (atomically thin) materials. Levitation platforms built by the investigatory team are based on the resonantly amplified radiation pressure of laser beams. This new type of optical levitation can provide ultimate isolation of the systems from external noise, making them extremely responsive to subtle environmental changes. These platforms could be turned into sharp instruments for measuring metrological variables of interest and probing new physics. Quantum optical techniques could be developed to optimise the sensitivity of levitated systems to levels that allow the exploration of quantum and gravitational physics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100004
Funder
Australian Research Council
Funding Amount
$502,453.00
Summary
Semiconductor laser for adaptive optics in astronomy and space awareness. This project aims to create a laser system for use as a laser guide star. Semiconductor laser technology is a cost effective, highly reliable and compact alternative to expensive, inefficient, bulky laser systems. This laser has wide scientific appeal for research with telescopes in astronomy, and for satellite tracking and mitigation of the threat of space debris. Producing a sodium laser guide star in Australia is expect ....Semiconductor laser for adaptive optics in astronomy and space awareness. This project aims to create a laser system for use as a laser guide star. Semiconductor laser technology is a cost effective, highly reliable and compact alternative to expensive, inefficient, bulky laser systems. This laser has wide scientific appeal for research with telescopes in astronomy, and for satellite tracking and mitigation of the threat of space debris. Producing a sodium laser guide star in Australia is expected to secure the country's position as the premier provider of commercial-grade laser guide star adaptive optics systems for civil and defence telescopes around the world.Read moreRead less
High-cadence near-infrared imaging. This project aims to deploy a cryogenic camera system to improve the outputs of astronomical telescopes. The system is equipped with an emerging detector technology, a near-infrared Avalanche Photo-Diode array, capable of high cadence imaging with frame rates of 10 - 1,000 Hz at a wavelength of around 2.2 microns. This new technology is a key component to the future of adaptive optics systems for astronomical telescopes as it allows the rapid measurements nece ....High-cadence near-infrared imaging. This project aims to deploy a cryogenic camera system to improve the outputs of astronomical telescopes. The system is equipped with an emerging detector technology, a near-infrared Avalanche Photo-Diode array, capable of high cadence imaging with frame rates of 10 - 1,000 Hz at a wavelength of around 2.2 microns. This new technology is a key component to the future of adaptive optics systems for astronomical telescopes as it allows the rapid measurements necessary to correct the image blurring introduced by the Earth's atmosphere. No expertise currently exists in Australia with this new technology. Capitalising on previous investment, the camera system is intended to fill a capability gap in local expertise and to ensure the potential of the next generation of telescopes is realised and strengthen our competitive edge for frontier instrumentation across the wider Australian imaging community.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100194
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Optical diagnostics for the investigation of high-speed energetic processes. Optical diagnostics for the investigation of high-speed energetic processes:
The project seeks to establish equipment to enable the investigation of high-speed energetic processes. Such processes, where large amounts of energy are released over a short time frame, occur in nature and almost every field of science and engineering, and their investigation is a formidable challenge. This challenge is designed to be met th ....Optical diagnostics for the investigation of high-speed energetic processes. Optical diagnostics for the investigation of high-speed energetic processes:
The project seeks to establish equipment to enable the investigation of high-speed energetic processes. Such processes, where large amounts of energy are released over a short time frame, occur in nature and almost every field of science and engineering, and their investigation is a formidable challenge. This challenge is designed to be met through the combined use of state-of-the-art flow visualisation, thermography and spectrometry equipment. These diagnostics would open avenues into so far impossible or difficult to conduct research on highly transient phenomena in various research fields, which include various aspects of fluid mechanics, combustion, and fracture mechanics. The equipment would be instrumental in the design of better and innovative machines, materials, instruments and processes.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100035
Funder
Australian Research Council
Funding Amount
$4,958,927.00
Summary
ARC Training Centre for Hyphenated Analytical Separation Technologies . The toughest analytical science challenges typically require advanced analytical technologies to acquire the desired solutions. In the field of separation science this inevitably involves hyphenated separation technologies, specifically the combination of chromatography and mass spectrometry. Advancing this technology to its full capability requires the collaborative strength of academic, industry and end-user partnerships, ....ARC Training Centre for Hyphenated Analytical Separation Technologies . The toughest analytical science challenges typically require advanced analytical technologies to acquire the desired solutions. In the field of separation science this inevitably involves hyphenated separation technologies, specifically the combination of chromatography and mass spectrometry. Advancing this technology to its full capability requires the collaborative strength of academic, industry and end-user partnerships, providing the materials and inspiration for young researchers to apply novel hyphenated methods to complex environmental and industrial systems. This Centre will deliver fundamental developments in hyphenated technologies, new analytical capability, and applied outcomes across multiple end-user groups and interests. Read moreRead less
Australian Laureate Fellowships - Grant ID: FL150100019
Funder
Australian Research Council
Funding Amount
$3,041,282.00
Summary
Precision laser levitation for quantum metrology and gravitational sensing. Precision laser levitation for quantum metrology and gravitational sensing: This fellowship project aims to levitate macroscopic objects using only laser beams, to provide a new tool to test physics theories. Strong laser beams can exert sufficient force to counteract gravity and make an object levitate. In contrast to other forms of levitation, laser levitation is scatter-free and can preserve system coherence. It has s ....Precision laser levitation for quantum metrology and gravitational sensing. Precision laser levitation for quantum metrology and gravitational sensing: This fellowship project aims to levitate macroscopic objects using only laser beams, to provide a new tool to test physics theories. Strong laser beams can exert sufficient force to counteract gravity and make an object levitate. In contrast to other forms of levitation, laser levitation is scatter-free and can preserve system coherence. It has superior optical and mechanical quality factors and complete information of the system dynamics is retained. This allows laser levitation to be turned into a highly controllable and ultra-sensitive device capable of detecting minute environmental changes. This research aims to probe the relationship between quantum and gravitational physics and develop laser levitation into a precision instrument for the sensing of gravity. Laser levitation has the potential to be developed into technology for mineral exploration and environmental sensing.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100124
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Rapid prototyping 3-D nano-pattern large area writer . Rapid prototyping 3-D nano-pattern large area writer:
The project aims to establish a nanoscale three-dimensional patterning rapid prototyping capability to enable advanced nanofabrication research and development. The extension of patterning nanostructured materials in three dimensions with nanometre resolution, developed for semiconductor processing, to nano-electronics, nanophotonics, nanosensors, nanobiotechnology and fundamental studi ....Rapid prototyping 3-D nano-pattern large area writer . Rapid prototyping 3-D nano-pattern large area writer:
The project aims to establish a nanoscale three-dimensional patterning rapid prototyping capability to enable advanced nanofabrication research and development. The extension of patterning nanostructured materials in three dimensions with nanometre resolution, developed for semiconductor processing, to nano-electronics, nanophotonics, nanosensors, nanobiotechnology and fundamental studies of nanoscale phenomena in science and engineering has opened new opportunities in these areas. As these areas accelerate, there is a need to develop nanoscale patterns and structures via rapid prototyping pathways and with methods accessible to an ever-diverse researcher base without a background in nanofabrication. By establishing the first NanoFrazor in Australia, this project aims to provide new technology for the fabrication of high-resolution nanoscale structures and patterns.
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ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to unde ....ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to understand how single cells react to and communicate with their surroundings. This science will underpin a new generation of devices capable of probing the response of cells within individuals to environmental conditions or treatment, creating innovative and powerful new sensing platforms.Read moreRead less