Pro-Fluorescent Aryl Nitroxides: New Probes for Polymer Lifetime and Kinetics Research. Internal aryl rings present in novel probes developed for this project impart fluorescence which is efficiently and internally quenched by the presence of a paramagnetic nitroxide group. Scavenging of radicals by the nitroxide however "switches on" the fluorescence and this enables powerful new fluorescence-based detection levels for the technique of nitroxide free radical scavenging. Such sensitivity is a ....Pro-Fluorescent Aryl Nitroxides: New Probes for Polymer Lifetime and Kinetics Research. Internal aryl rings present in novel probes developed for this project impart fluorescence which is efficiently and internally quenched by the presence of a paramagnetic nitroxide group. Scavenging of radicals by the nitroxide however "switches on" the fluorescence and this enables powerful new fluorescence-based detection levels for the technique of nitroxide free radical scavenging. Such sensitivity is applicable to polymerization kinetics studies, as well as providing new means for the determination of materials lifetimes. The development of pro-fluorescent markers as indicators for polymer degradation would be a significant outcome for materials where component failure has a major negative impact.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989946
Funder
Australian Research Council
Funding Amount
$357,000.00
Summary
High Resolution LC/MS and MALDI for Molecular and Macromolecular Characterisation. The provision of high-resolution and matrix assisted laser desorption ionisation mass spectrometers configured for the molecular and macromolecular research of high quality research groups will lead to earlier and better fundamental discoveries that are directed at important practical developments in medicine, biotechnology, nanotechnology, light-energy harvesting, polymer materials and sensors. These include anti ....High Resolution LC/MS and MALDI for Molecular and Macromolecular Characterisation. The provision of high-resolution and matrix assisted laser desorption ionisation mass spectrometers configured for the molecular and macromolecular research of high quality research groups will lead to earlier and better fundamental discoveries that are directed at important practical developments in medicine, biotechnology, nanotechnology, light-energy harvesting, polymer materials and sensors. These include anticancer agents, nanodevices for drug delivery, better polymers with more energy efficient industrial processes, bioactive molecules for industrially important nitrogen fixation and many more. Read moreRead less
Novel Complex Architecture Polymers via a Combination of RAFT Chemistry and Pericyclic Reactions: Synthesis and Characterization. The project aims at advancing the synthetic limits and broadening the synthetic scope of living free radical polymerization and thus enhancing the library of polymer structures available for applications ranging from drug delivery to opto-electronics. Current material design for these applications is yet to reach its full potential through innovative synthetic approac ....Novel Complex Architecture Polymers via a Combination of RAFT Chemistry and Pericyclic Reactions: Synthesis and Characterization. The project aims at advancing the synthetic limits and broadening the synthetic scope of living free radical polymerization and thus enhancing the library of polymer structures available for applications ranging from drug delivery to opto-electronics. Current material design for these applications is yet to reach its full potential through innovative synthetic approaches. The proposal critically underpins and further advances Australia's leading position in both breakthrough science as well as advanced materials. Due to its significant scientific breadth and large coverage of both synthetic and physical aspects of polymer science, the project also provides a significant platform for research training at both honours and PhD level.Read moreRead less
Reversible Addition Fragmentation Chain Transfer (RAFT) Free Radical Copolymerizations of Various Monomers. The proposed project will investigate the structure and properties of statistical copolymers prepared via living free radical polymerization. We will study the characteristics of a wide variety of Reversible Addition Fragmentation Chain Transfer (RAFT) copolymerizations using a range of monomers, including those interesting for biomedical and material science applications. We expect to gai ....Reversible Addition Fragmentation Chain Transfer (RAFT) Free Radical Copolymerizations of Various Monomers. The proposed project will investigate the structure and properties of statistical copolymers prepared via living free radical polymerization. We will study the characteristics of a wide variety of Reversible Addition Fragmentation Chain Transfer (RAFT) copolymerizations using a range of monomers, including those interesting for biomedical and material science applications. We expect to gain a deeper understanding of the influence of the RAFT process on the kinetics and mechanism of copolymerization and the properties of the resulting polymers in order to tailor specific polymer materials for biomedial applications.Read moreRead less
ARC Centre of Excellence - Centre for Free Radical Chemistry and Biotechnology. Free radical chemistry is of increasing importance in the manufacture of improved plastics, paints and related materials, in helping restrict oxidative processes that can lead to adverse human health and also to the degradation of important industrial materials. The research will contribute to promoting & maintaining good health by developing new methods for reducing the impacts of ageing as well as in the treatment ....ARC Centre of Excellence - Centre for Free Radical Chemistry and Biotechnology. Free radical chemistry is of increasing importance in the manufacture of improved plastics, paints and related materials, in helping restrict oxidative processes that can lead to adverse human health and also to the degradation of important industrial materials. The research will contribute to promoting & maintaining good health by developing new methods for reducing the impacts of ageing as well as in the treatment of several life-threatening conditions such as stroke. Industrial applications include better surface coatings for preserving metals, and additives to improve the quality and shelf life of beer and wines.Read moreRead less
New Fluorescent Probes to Elucidate Complex Oxidation Mechanisms. From medicine to manufacturing, polymers ("plastics") are a major component in the materials we use in our modern society, yet the manner by which they degrade and break down is often not well understood. Controlling the lifetime of polymers by either accelerating degradation on the one hand or preventing, or limiting, it on the other, will have significant benefits to society but this can only be achieved by reaching a thorough u ....New Fluorescent Probes to Elucidate Complex Oxidation Mechanisms. From medicine to manufacturing, polymers ("plastics") are a major component in the materials we use in our modern society, yet the manner by which they degrade and break down is often not well understood. Controlling the lifetime of polymers by either accelerating degradation on the one hand or preventing, or limiting, it on the other, will have significant benefits to society but this can only be achieved by reaching a thorough understanding of the degradation process. This project makes use of a unique, Australian-designed additive which stabilises polymeric materials, provides a marker for degradation levels and also provides information about the nature of the degradation processes occurring within polymers.Read moreRead less
Synthesis of oligomers in dense carbon dioxide. The aim of the project is to develop a novel technique for the synthesis of low molecular weight polymers (oligomers) using dense carbon dioxide as a polymerisation solvent. The use of elevated pressure is the major impediment to the commercialisation of such technology. The technique proposed in this project will enable oligomers to be produced at greatly reduced operating pressures and may lead to a more general procedure for conducting other t ....Synthesis of oligomers in dense carbon dioxide. The aim of the project is to develop a novel technique for the synthesis of low molecular weight polymers (oligomers) using dense carbon dioxide as a polymerisation solvent. The use of elevated pressure is the major impediment to the commercialisation of such technology. The technique proposed in this project will enable oligomers to be produced at greatly reduced operating pressures and may lead to a more general procedure for conducting other types of polymer synthesis in dense carbon dioxide.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668038
Funder
Australian Research Council
Funding Amount
$175,000.00
Summary
From Fundamentals to Complex Architecture in Free-Radical Polymerisation: Designing Future Generations of Macromolecular Materials. This research will help maintain the profile of Australia as a serious player in the important field of polymer chemistry. It will lay the groundwork for the preparation of novel materials of commercial value. These materials will enable more effective use of Australia's natural resources, support the development of high value-added Australian manufacturing industri ....From Fundamentals to Complex Architecture in Free-Radical Polymerisation: Designing Future Generations of Macromolecular Materials. This research will help maintain the profile of Australia as a serious player in the important field of polymer chemistry. It will lay the groundwork for the preparation of novel materials of commercial value. These materials will enable more effective use of Australia's natural resources, support the development of high value-added Australian manufacturing industries, and find application in human and animal medicine. They will enhance the health and well-being of the Australian community and engender a sense of wonder in susceptible members of this community.Read moreRead less
Structure-Property Relationships of Polymers with Controlled Architecture. Mechanical properties of a polymer (e.g., how elastic it is and how it dissipates energy when compressed) govern how well it performs as an adhesive, or its behaviour when melted and shaped into a consumer item. This project aims to relate molecular architecture to mechanical properties, using new techniques which permit the creation of polymers wherein each architectural characteristic is separately controlled. This has ....Structure-Property Relationships of Polymers with Controlled Architecture. Mechanical properties of a polymer (e.g., how elastic it is and how it dissipates energy when compressed) govern how well it performs as an adhesive, or its behaviour when melted and shaped into a consumer item. This project aims to relate molecular architecture to mechanical properties, using new techniques which permit the creation of polymers wherein each architectural characteristic is separately controlled. This has the potential to develop fundamental understanding for structure-property relations for the type of branched polymers that are in common use in industry and for which adequate models do not currently exist.Read moreRead less
Nanoporous Epoxy Thermosets via Microphase Separation of Block Copolymers. This project has many expected outcomes and benefits to Australia: (1) Development of the first technology to produce nanoporous epoxy thermosets (i.e. epoxy nanofoams) that may have many applications in microelectronics, optical waveguides and biological separations; (2) Providing impetus for an advanced materials synthesis and manufacturing industry for Australia and contributing to the Frontier Technologies National Re ....Nanoporous Epoxy Thermosets via Microphase Separation of Block Copolymers. This project has many expected outcomes and benefits to Australia: (1) Development of the first technology to produce nanoporous epoxy thermosets (i.e. epoxy nanofoams) that may have many applications in microelectronics, optical waveguides and biological separations; (2) Providing impetus for an advanced materials synthesis and manufacturing industry for Australia and contributing to the Frontier Technologies National Research Priority-Advanced Materials Priority Goals; (3) The development of new niche markets with these new materials and the new technologies, which is an excellent vehicle for Australia to move to a high-value added industrial portfolio that maximises return and promotes job growth.Read moreRead less