Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide t ....Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide targets and/or concepts for the pharmacotherapy of obesity.Read moreRead less
Understanding meal patterns: developing the evidence-base for nutrition messages. Little is known about the format, structure or context of meal patterns despite their importance for health. This project will examine the predictors of meal patterns of Australians. This will provide new information which will facilitate the design of more effective ways to communicate with consumers about healthy eating.
Reforming evidence synthesis and translation for food and nutrition policy. This project aims to develop and evaluate a ‘Fit-for-Purpose’ framework to strategically guide evidence synthesis and translation for food and nutrition policies in order to effectively and safely tackle contemporary nutrition and food security problems. The project intends to use interdisciplinary approaches that integrate nutrition science, health promotion and policy science. The project would also examine policy-make ....Reforming evidence synthesis and translation for food and nutrition policy. This project aims to develop and evaluate a ‘Fit-for-Purpose’ framework to strategically guide evidence synthesis and translation for food and nutrition policies in order to effectively and safely tackle contemporary nutrition and food security problems. The project intends to use interdisciplinary approaches that integrate nutrition science, health promotion and policy science. The project would also examine policy-maker acceptance of the framework. Expected project outcomes include an enhanced capacity to critically analyse existing policies and guide future food and nutrition policy formulation and evaluation. This project would provide significant benefits by helping to promote public health, wellbeing and food system sustainability.Read moreRead less
Understanding personal, social and environmental influences on nutrition and physical activity among older adults living in urban and rural areas. There are negative impacts of obesity, poor diet and physical inactivity on physical, psychological and social wellbeing and national economic costs associated with these burdens are substantial. Obesity and its associated illnesses are estimated to cost Australian health services $1.2 billion a year. An understanding of the modifiable determinants of ....Understanding personal, social and environmental influences on nutrition and physical activity among older adults living in urban and rural areas. There are negative impacts of obesity, poor diet and physical inactivity on physical, psychological and social wellbeing and national economic costs associated with these burdens are substantial. Obesity and its associated illnesses are estimated to cost Australian health services $1.2 billion a year. An understanding of the modifiable determinants of nutrition and physical activity behaviours is required in order to develop effective interventions to promote health and well-being. Promoting physical activity and a healthy diet thus has the potential to substantially reduce the burden of disease in Australia and improve quality of life.Read moreRead less
Smells that 'taste': Flavour perception and its consequences. The experience of flavour during eating and drinking has surprising social and economic ramifications. Our preference for sweet and fatty food has contributed to progressive increases in body mass over the last twenty years. Many experts now consider this to be a major public health crisis in the making. Economically, Australia is heavily dependent upon food exports, both in terms of primary production and value added processed food ....Smells that 'taste': Flavour perception and its consequences. The experience of flavour during eating and drinking has surprising social and economic ramifications. Our preference for sweet and fatty food has contributed to progressive increases in body mass over the last twenty years. Many experts now consider this to be a major public health crisis in the making. Economically, Australia is heavily dependent upon food exports, both in terms of primary production and value added processed food. Understanding the psychology of flavour, which is central to this project, should assist the development of non-fattening additives that appreciably alter fat and sweetness perception, creating new food products that are healthy, preferred and potential export earners. Read moreRead less
Accuracy and cost-effectiveness of technology-assisted dietary assessment. This project aims to compare leading methods for technology-assisted dietary assessment. Excessive cost and questionable accuracy limit the routine use of dietary assessment and undermine decision making in Australia. This project intends to compare three technology methods of assessing diet with the current standard recall method used in population surveys in order to confirm if the use of food images and automated metho ....Accuracy and cost-effectiveness of technology-assisted dietary assessment. This project aims to compare leading methods for technology-assisted dietary assessment. Excessive cost and questionable accuracy limit the routine use of dietary assessment and undermine decision making in Australia. This project intends to compare three technology methods of assessing diet with the current standard recall method used in population surveys in order to confirm if the use of food images and automated methods provide new approaches to improve accuracy and consumer acceptability. Expected outcomes of this project include more accurate and acceptable methods of assessing dietary intake. These findings will inform decision making for researchers, policy makers and practitioners in Australia, and potentially lead to more regular population surveillance.Read moreRead less
The cortical location of hunger and thirst: a multifunctional study in sheep. The escalating problems associated with obesity are immense. These effects contribute to a global epidemic that now eclipses both infectious diseases and (ironically) undernutrition in its proportions. The effects of disorders of thirst are less apparent but potentially devastating albeit on a smaller scale. The elderly and psychotic in the community have impaired thirst mechanisms which impacts on their life in a dra ....The cortical location of hunger and thirst: a multifunctional study in sheep. The escalating problems associated with obesity are immense. These effects contribute to a global epidemic that now eclipses both infectious diseases and (ironically) undernutrition in its proportions. The effects of disorders of thirst are less apparent but potentially devastating albeit on a smaller scale. The elderly and psychotic in the community have impaired thirst mechanisms which impacts on their life in a dramatic way particularly during prolonged hot weather. The aims of these experiments are to understand the basic brain mechanisms that underpin these drives. This understanding will have far reaching repercussions for the community both in terms of promoting good health and in preventative health care.
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Drosophila Quantitative Genomics. This research proposal will be a key element in the emerging program in evolutionary and ecological functional genomics at the University of Queensland. Our studies utilize modern genomics approaches to address diverse national priorities from conservation of biological resources in the face of climate change, to understanding how genetic history contributes to drug susceptibility. The research will contribute to the intellectual foundation upon which rigorous ....Drosophila Quantitative Genomics. This research proposal will be a key element in the emerging program in evolutionary and ecological functional genomics at the University of Queensland. Our studies utilize modern genomics approaches to address diverse national priorities from conservation of biological resources in the face of climate change, to understanding how genetic history contributes to drug susceptibility. The research will contribute to the intellectual foundation upon which rigorous environmental and biomedical research is built. Social impact will be seen in the training of a new generation of integrative genome biologists, and the shaping of attitudes toward the role of genetics in human biology.Read moreRead less
Understanding environmental drivers of socioeconomic inequalities in food consumption. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Improving Australians' diet will cut health care costs, improve quality of life, and promote physical, mental and social functioning. In o ....Understanding environmental drivers of socioeconomic inequalities in food consumption. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Improving Australians' diet will cut health care costs, improve quality of life, and promote physical, mental and social functioning. In order to improve diet, particularly among those who are disadvantaged, a better understanding of the environmental drivers of inequalities in food consumption is required. Findings will inform the development of policies to increase the availability and accessibility of foodstuffs to supply an adequate and affordable diet for all.Read moreRead less
Food and trust. The health, well-being and productivity of Australian society is absolutely dependent on a trusted food system. By knowing more about consumer trust in the food system, and in expert advice, we can better tailor ways to improve communication about health and food. We may avoid the problems that have developed in countries where low public trust has damaged the effectiveness of the systems to keep food safe and healthy, and in government and industry efforts to promote better eati ....Food and trust. The health, well-being and productivity of Australian society is absolutely dependent on a trusted food system. By knowing more about consumer trust in the food system, and in expert advice, we can better tailor ways to improve communication about health and food. We may avoid the problems that have developed in countries where low public trust has damaged the effectiveness of the systems to keep food safe and healthy, and in government and industry efforts to promote better eating habits. We will also be able to compare results with those in Europe to gain an international perspective on food trust.Read moreRead less