Metallosupramolecular Cages for Enantioselective Applications. The project aims to explore new synthetic routes to functional supramolecular cages/containers which are able to selectively host small molecules in their interior space, and may provide feedback upon the presence of a guest (i.e. molecular sensing) or catalyse reactions within the enclosed cavity. The project expects to produce chiral cages that are capable of detecting specific enantiomers in solution and act upon them. The expecte ....Metallosupramolecular Cages for Enantioselective Applications. The project aims to explore new synthetic routes to functional supramolecular cages/containers which are able to selectively host small molecules in their interior space, and may provide feedback upon the presence of a guest (i.e. molecular sensing) or catalyse reactions within the enclosed cavity. The project expects to produce chiral cages that are capable of detecting specific enantiomers in solution and act upon them. The expected outcome is a deeper understanding of the structure/property relationship of these novel species and steps towards application. This should provide benefits given the application of solution-based methods for enantioselective sensing/catalysis are of significance in high-value pharmaceutical synthesis.Read moreRead less
Opening Up Access to L-Sugars through a Synergy of Experiment and Theory. This project aims to address a major bottleneck in the science of carbohydrates by developing the first broad-scope synthetic routes to L-sugars. L-sugars are critical components of many biologically and commercially significant molecules, but knowledge of their functional roles is impeded by the fact that most L-sugars are expensive or difficult to make. This project expects to develop expeditious routes to L-sugars via a ....Opening Up Access to L-Sugars through a Synergy of Experiment and Theory. This project aims to address a major bottleneck in the science of carbohydrates by developing the first broad-scope synthetic routes to L-sugars. L-sugars are critical components of many biologically and commercially significant molecules, but knowledge of their functional roles is impeded by the fact that most L-sugars are expensive or difficult to make. This project expects to develop expeditious routes to L-sugars via an innovative combination of synthetic and theoretical chemistry. Expected outcomes include a markedly increased capacity to access pure samples of L-sugar-based biomolecules, as needed for studying their biological functions. Significant benefits in the development of vaccines, diagnostics and biomaterials are anticipated.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100148
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
An X-ray scattering facility for bulk and interfacial nanostructure. This project aims to establish an integrated, three-beamline facility for small- and wide-angle x-ray scattering (SWAXS) investigations of nanostructured materials in the bulk phase and at surfaces, focussed on soft and self-assembled materials such as polymers, biomaterials and molecular gels. This facility will act as a node for researchers in and around Sydney, providing research tools and training in small-angle scattering. ....An X-ray scattering facility for bulk and interfacial nanostructure. This project aims to establish an integrated, three-beamline facility for small- and wide-angle x-ray scattering (SWAXS) investigations of nanostructured materials in the bulk phase and at surfaces, focussed on soft and self-assembled materials such as polymers, biomaterials and molecular gels. This facility will act as a node for researchers in and around Sydney, providing research tools and training in small-angle scattering. It will provide cutting-edge research tools and advanced training in small-angle scattering. It is expected to yield important science in its own right, and enable researchers to more effectively use beamlines at Australian and international major research facilities.Read moreRead less
Nanostructured Ionic-Molecular Hybrid Liquids. This project aims to produce a new class of green, economical, non-toxic, low volatility, designer solvents from mixtures of one or more molecular components, and ionic liquid-inspired salts. By manipulating the intermolecular forces between components of these nanostructured ionic molecular "hybrid liquids" (HLs), we will develop new understanding of how liquid structure arises from the nano- to the colloidal and even micro-scale. HLs will enable ....Nanostructured Ionic-Molecular Hybrid Liquids. This project aims to produce a new class of green, economical, non-toxic, low volatility, designer solvents from mixtures of one or more molecular components, and ionic liquid-inspired salts. By manipulating the intermolecular forces between components of these nanostructured ionic molecular "hybrid liquids" (HLs), we will develop new understanding of how liquid structure arises from the nano- to the colloidal and even micro-scale. HLs will enable the development novel complex fluids, which are liquids containing interacting particles, polymers, and/or surfactants. Lubricants developed from HL based complex fluids will act as a “test-bed” application for the new understanding this project will engender, towards use of HLs in diverse areas.Read moreRead less
Spatially orthogonal multifunctional materials for catalytic cascades. This project aims to develop and implement new strategies to create, visualise, and apply multifunctional catalysts in which the location of (and communication between) active sites is precisely controlled to unlock ultraselective cascade reactions. Catalysis is a key enabling technology contributing to 35 % of the global economy, with new catalysts underpinning socioeconomic advancement through fuels, chemicals, and pharmace ....Spatially orthogonal multifunctional materials for catalytic cascades. This project aims to develop and implement new strategies to create, visualise, and apply multifunctional catalysts in which the location of (and communication between) active sites is precisely controlled to unlock ultraselective cascade reactions. Catalysis is a key enabling technology contributing to 35 % of the global economy, with new catalysts underpinning socioeconomic advancement through fuels, chemicals, and pharmaceuticals production, and environmental depollution. This interdisciplinary project expects to discover next-generation nanoengineered catalysts, and to develop innovative energy- and resource-efficient chemical processes, which should offer significant benefits to Australian science, industry, and the environment.Read moreRead less
Three-dimensional printing of functional polymers. This project aims to develop methods to three-dimensional (3D) print functional polymer inks to create advanced objects with engineered properties. Additive manufacturing has the ability to transform industries bringing manufacturing into local business and homes. However, for the true potential to be met, innovative polymer inks need to be developed. This project will develop innovative polymer inks as raw materials for affordable 3D printers. ....Three-dimensional printing of functional polymers. This project aims to develop methods to three-dimensional (3D) print functional polymer inks to create advanced objects with engineered properties. Additive manufacturing has the ability to transform industries bringing manufacturing into local business and homes. However, for the true potential to be met, innovative polymer inks need to be developed. This project will develop innovative polymer inks as raw materials for affordable 3D printers. It will prepare a range of polymer inks that respond and change their properties in response to their environment, for example a temperature switch. This will enable printed objects to perform complex tasks such as shape shifting and self-healing.Read moreRead less
Spatially orthogonal multifunctional materials for catalytic cascades. This project aims to develop and implement new strategies to create, visualise, and apply multifunctional catalysts in which the location of (and communication between) active sites is precisely controlled to unlock ultraselective cascade reactions. Catalysis is a key enabling technology contributing to 35 % of the global economy, with new catalysts underpinning socioeconomic advancement through fuels, chemicals, and pharmace ....Spatially orthogonal multifunctional materials for catalytic cascades. This project aims to develop and implement new strategies to create, visualise, and apply multifunctional catalysts in which the location of (and communication between) active sites is precisely controlled to unlock ultraselective cascade reactions. Catalysis is a key enabling technology contributing to 35 % of the global economy, with new catalysts underpinning socioeconomic advancement through fuels, chemicals, and pharmaceuticals production, and environmental depollution. This interdisciplinary project expects to discover next-generation nanoengineered catalysts, and to develop innovative energy- and resource-efficient chemical processes, which should offer significant benefits to Australian science, industry, and the environment.Read moreRead less
Turning homogeneous catalysts into heterogeneous catalysts: Robust linking of organometallic complexes onto inert carbon supports. Improvement in the sustainability of fine chemical synthesis is urgently required to meet the increasing demand for new pharmaceuticals. This project will develop new approaches to catalyst immobilisation, to enhance catalyst recovery, as well as to the characterisation of such catalysts for understanding structure and mechanism.
Linkage Infrastructure, Equipment And Facilities - Grant ID: Le170100148
Funder
Australian Research Council
Summary
An X-ray scattering facility for bulk and interfacial nanostructure. This project aims to establish an integrated, three-beamline facility for small- and wide-angle x-ray scattering (SWAXS) investigations of nanostructured materials in the bulk phase and at surfaces, focussed on soft and self-assembled materials such as polymers, biomaterials and molecular gels. This facility will act as a node for researchers in and around Sydney, providing research tools and training in small-angle scattering. ....An X-ray scattering facility for bulk and interfacial nanostructure. This project aims to establish an integrated, three-beamline facility for small- and wide-angle x-ray scattering (SWAXS) investigations of nanostructured materials in the bulk phase and at surfaces, focussed on soft and self-assembled materials such as polymers, biomaterials and molecular gels. This facility will act as a node for researchers in and around Sydney, providing research tools and training in small-angle scattering. It will provide cutting-edge research tools and advanced training in small-angle scattering. It is expected to yield important science in its own right, and enable researchers to more effectively use beamlines at Australian and international major research facilities.Read moreRead less
Metal-organic frameworks as heterogeneous catalytic systems. Catalysts of industrial chemical processes that are soluble in the reaction mixture are often less stable and harder to separate from the products. This project will tackle these issues by integrating such catalysts into an open framework material that combines the advantages of both soluble and insoluble catalysts - a hybrid catalytic material.