Nanoparticle formulations for DNA-targeted radiotherapy and imaging: combinations with chromatin-modifying compounds. This project will develop a new approach for treating and imaging cancer using nanoparticles which target specific cells for cancer therapy and diagnostic imaging. The nanoparticles will be combined with compounds that alter the architecture of DNA to make therapy more effective and to improve the safety of imaging.
Industrial Transformation Training Centres - Grant ID: IC170100016
Funder
Australian Research Council
Funding Amount
$3,123,492.00
Summary
ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therap ....ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therapeutics. The use of an individual patient’s cellular and molecular research findings will ultimately enable personalised diagnostic and therapeutic decisions.Read moreRead less
Synthetic extracellular matrices for control of cellular reprogramming. This project aims to design materials that control the cellular environment for the fast, efficient, and reproducible production of reprogrammed cells in embryo-like architectures. Regenerative medicine has entered a new era, where reprogramming a patient’s cells is now possible for studying and treating disease. The expected outcomes of this project include mechanistic details of cell reprogramming, design rules for 3D prin ....Synthetic extracellular matrices for control of cellular reprogramming. This project aims to design materials that control the cellular environment for the fast, efficient, and reproducible production of reprogrammed cells in embryo-like architectures. Regenerative medicine has entered a new era, where reprogramming a patient’s cells is now possible for studying and treating disease. The expected outcomes of this project include mechanistic details of cell reprogramming, design rules for 3D printing of living cells and commercially viable reprogramming materials. The project expects to contribute fundamental knowledge in materials and biomedical sciences, while providing tools that will benefit commercial ventures in cell and tissue manufacturing.Read moreRead less