Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis for a novel biosensor utilising mechanosensitive ion channels incorporated into an artificial lipid bilayer membrane. To support this outcome, the project will develop the planar patch-clamp electrophysiology recording techniques suitable for l ....Development of planar patch-clamp electrophysiology to investigate liposome-based artificial nanosensor devices. This project aims to characterise the interaction of transport proteins with unsupported lipid bilayer membranes. This will provide the basis for a novel biosensor utilising mechanosensitive ion channels incorporated into an artificial lipid bilayer membrane. To support this outcome, the project will develop the planar patch-clamp electrophysiology recording techniques suitable for liposomes. This provides a significant PhD training opportunity and brings an international focus to the development of planar patch-clamp electrophysiology in Australia. The project has significant commercial potential by developing both the planar patch-clamp electrophysiology techniques for liposomes and producing a novel biomimetic mechanosensitive biosensor.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882778
Funder
Australian Research Council
Funding Amount
$201,224.00
Summary
Water vapour radiometers for millimetre-wave phase correction for the Australia Telescope. Australia has a tradition of excellence in astronomy. Inspired by wonder about the cosmos, it stimulates public interest in science, so leading to the training of highly skilled graduates. In turn, this drives the development of technologies needed to pursue the science. The nation has invested in the technology for millimetre-wave astronomy, building the first interferometer in our hemisphere. This equipm ....Water vapour radiometers for millimetre-wave phase correction for the Australia Telescope. Australia has a tradition of excellence in astronomy. Inspired by wonder about the cosmos, it stimulates public interest in science, so leading to the training of highly skilled graduates. In turn, this drives the development of technologies needed to pursue the science. The nation has invested in the technology for millimetre-wave astronomy, building the first interferometer in our hemisphere. This equipment will capitalise on this investment, extending the capabilities of the Australia Telescope to maintain it as a front line instrument, attracting the best scientists here to use it. This will help nurture a vigorous radio-science community, one able to actively participate in the billion-dollar investment being made internationally in the field.Read moreRead less
International collaboration in gravitational wave data analysis, simulations and third generation detectors. The project brings together seven outstanding international researchers into close collaboration with an Australian team to develop new techniques for finding gravitational wave signals in the vast archive of data they have helped to collect, as well as developing and testing theory for improved detectors that operate with sensitivity beyond the limits set by classical physics. The projec ....International collaboration in gravitational wave data analysis, simulations and third generation detectors. The project brings together seven outstanding international researchers into close collaboration with an Australian team to develop new techniques for finding gravitational wave signals in the vast archive of data they have helped to collect, as well as developing and testing theory for improved detectors that operate with sensitivity beyond the limits set by classical physics. The project will utilize a state of the art supercomputer and the superb national facility for high power laser interferometry at Gingin, Western Australia. Read moreRead less
Star Formation at Millimetre Wavelengths with the CSIRO Australia Telescope. The newly-upgraded CSIRO Australia Telescope Compact Array, together with the CSIRO Mopra Telescope, provide a unique and powerful combination for studying the millimetre-wave emission from molecules and cold dust in star formation regions. We propose to combine the astrophysical expertise of UNSW with the instrumental expertise of CSIRO to use these instruments to study the processes of star formation. There are two pa ....Star Formation at Millimetre Wavelengths with the CSIRO Australia Telescope. The newly-upgraded CSIRO Australia Telescope Compact Array, together with the CSIRO Mopra Telescope, provide a unique and powerful combination for studying the millimetre-wave emission from molecules and cold dust in star formation regions. We propose to combine the astrophysical expertise of UNSW with the instrumental expertise of CSIRO to use these instruments to study the processes of star formation. There are two parallel themes to this research: to commission and develop optimal techniques for using the new instruments, and to make use of them to explore the poorly-understood processes that cause stars to form.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560685
Funder
Australian Research Council
Funding Amount
$451,000.00
Summary
Scanning Probe Microscopy for Bioelectrochemistry. New methods to study the fundamental properties of biological samples, in particular proteins, are continuing to advance and impact on society. We will establish a leading edge facility for high-resolution imaging of biomolecules with redox functions. This will enable the continued development of new enzyme based diagnostic tests by understanding the dynamic nature of coupled electron and molecular interactions with redox enzymes in solution. Th ....Scanning Probe Microscopy for Bioelectrochemistry. New methods to study the fundamental properties of biological samples, in particular proteins, are continuing to advance and impact on society. We will establish a leading edge facility for high-resolution imaging of biomolecules with redox functions. This will enable the continued development of new enzyme based diagnostic tests by understanding the dynamic nature of coupled electron and molecular interactions with redox enzymes in solution. The bioelectrochemical imaging facility will be unique in Australia and establish an important cross-disciplinary approach within the international community.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775602
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
A ground station for the NANTEN2 sub-millimetre wave telescope. Australia has a tradition of excellence in astronomy. Inspired by our natural wonder about the cosmos, it helps stimulate public interest in science, so leading to the training of highly skilled graduates. This in turn drives development of technologies needed to pursue the science. The nation has invested in technology for millimetre-wave astronomy, building the first interferometer in our hemisphere. We aim to capitalise on this i ....A ground station for the NANTEN2 sub-millimetre wave telescope. Australia has a tradition of excellence in astronomy. Inspired by our natural wonder about the cosmos, it helps stimulate public interest in science, so leading to the training of highly skilled graduates. This in turn drives development of technologies needed to pursue the science. The nation has invested in technology for millimetre-wave astronomy, building the first interferometer in our hemisphere. We aim to capitalise on this investment, leveraging it to access a frontline facility under construction on the Atacama plateau in Chile. This will help nurture a vigorous radio-science community, one able to actively participate in the billion-dollar investment being made by the international community in astronomical facilities there.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347403
Funder
Australian Research Council
Funding Amount
$222,000.00
Summary
An ultra-wideband digital filterbank for the Mopra Radiotelescope. We seek funding to equip the Mopra radiotelescope with an ultra-wide-bandwidth digital filter bank. This will greatly improve the efficiency of the observatory, increasing the speed at which spectroscopic data is acquired by a factor of 8, and the speed of acquiring continuum data by a factor of 32. Once equipped in this way, Mopra, which is already the largest millimetre-wave radiotelescope in the southern hemisphere, will enjo ....An ultra-wideband digital filterbank for the Mopra Radiotelescope. We seek funding to equip the Mopra radiotelescope with an ultra-wide-bandwidth digital filter bank. This will greatly improve the efficiency of the observatory, increasing the speed at which spectroscopic data is acquired by a factor of 8, and the speed of acquiring continuum data by a factor of 32. Once equipped in this way, Mopra, which is already the largest millimetre-wave radiotelescope in the southern hemisphere, will enjoy an unbeatable edge over all other competing observatories around the world through its combination of collecting area and bandpass.Read moreRead less
Integration of Electrochemistry and Green Chemistry: A Roadmap for Scientific Innovation. Electrochemistry represents an enabling science in physical, chemical and life sciences. It plays a key role in fundamental studies and in Australia's industrial capacity to exploit emerging technologies. Research conducted synergistically within the ARC Centre for Green Chemistry would enable the Monash Electrochemistry Group to develop and exploit new concepts. In the national interest, the Fellowship ....Integration of Electrochemistry and Green Chemistry: A Roadmap for Scientific Innovation. Electrochemistry represents an enabling science in physical, chemical and life sciences. It plays a key role in fundamental studies and in Australia's industrial capacity to exploit emerging technologies. Research conducted synergistically within the ARC Centre for Green Chemistry would enable the Monash Electrochemistry Group to develop and exploit new concepts. In the national interest, the Fellowship would: facilitate global participation in cutting-edge science derived from electrochemical and green chemical concepts; provide commercial opportunities for new and mature chemical industries; expand postgraduate training; and promote technology exchange with Australian and international leading-edge research organisations.Read moreRead less
Control of Instabilities in Advanced Gravitational Wave Detectors. Gravitational wave technology from UWA has already given rise to significant spin-offs including sapphire oscillators for radar applications and vibration isolators for airborne mineral exploration. This project will lead to techniques for increasing the sensitivity of already extraordinary sensitive instruments, and could have applications in many areas. The project will strengthen Australia's role in the world wide quest to det ....Control of Instabilities in Advanced Gravitational Wave Detectors. Gravitational wave technology from UWA has already given rise to significant spin-offs including sapphire oscillators for radar applications and vibration isolators for airborne mineral exploration. This project will lead to techniques for increasing the sensitivity of already extraordinary sensitive instruments, and could have applications in many areas. The project will strengthen Australia's role in the world wide quest to detect gravitational waves, which is one of the most significant and challenging human endeavours. The project will use the superb national research facility at Gingin. Its content contributes to the Eureka Prize winning Gravity Discovery Centre also located at the site, which is a major centre for science education.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882977
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Enhanced NMR Research, Characterisation and Analysis Facility. Studying molecular species is at the heart of chemistry and biochemistry and fundamental to improving our understanding of molecular mechanisms and interactions. This becomes important for elucidating aspects of biological function, medicinal and pharmaceutical chemistry, materials science and synthetic methodology, which all underpin health and technology advances in Australia. The infrastructure will support projects involving fun ....Enhanced NMR Research, Characterisation and Analysis Facility. Studying molecular species is at the heart of chemistry and biochemistry and fundamental to improving our understanding of molecular mechanisms and interactions. This becomes important for elucidating aspects of biological function, medicinal and pharmaceutical chemistry, materials science and synthetic methodology, which all underpin health and technology advances in Australia. The infrastructure will support projects involving fundamental and strategic research spanning nanotechnology and the biological and materials sciences to industry-oriented projects.Read moreRead less