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Origin of genomically-encoded communication in animals: deciphering the role of peptide signalling in the sea sponge Amphimedon queenslandica. The purpose of this research is to understand the evolutionary origin and essential roles of peptide communication in humans and other animals. Knowledge gleaned from this study will shed light on how peptide signalling influences animal life at its most fundamental level, including potentially how abnormal cell communication causes disease.
Australian Laureate Fellowships - Grant ID: FL110100044
Funder
Australian Research Council
Funding Amount
$3,001,626.00
Summary
Origin, evolution and roles of cardinal genomic features underpinning animal multicellular complexity. As the first genome project from our oceans, the sea sponge Amphimedon heralds a new era of marine science for Australia. Using post-genomic approaches, this project will show how studying marine organisms can produce the most fundamental insights into not only multicellular life but also into human diseases and cancer that originally evolved from our oceans.