Nanosilver antimicrobial resistance in target pathogens. This project aims to elucidate the important phenomena of bacterial resistance to antimicrobial nanosilver, currently one of the most developed and commercialised products of nanotechnology. The integrated research approach comprises of concurrent identification of the origins and routes of nanosilver toxicity in bacteria and the arising emergence and mechanisms of bacterial defence to the toxicity. The generated knowledge is to form a bas ....Nanosilver antimicrobial resistance in target pathogens. This project aims to elucidate the important phenomena of bacterial resistance to antimicrobial nanosilver, currently one of the most developed and commercialised products of nanotechnology. The integrated research approach comprises of concurrent identification of the origins and routes of nanosilver toxicity in bacteria and the arising emergence and mechanisms of bacterial defence to the toxicity. The generated knowledge is to form a base template for novel nanosilver engineering with less tendency for resistance development and to facilitate tracking of resistance and its spread amongst microorganisms. The knowledge has far-reaching implications on the better governance of nanosilver use, including its disposal.Read moreRead less
The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling f ....The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Read moreRead less
Photoelectrocatalysis-based Techniques for Bactericidal Applications. Effective control of the quality of water supply is paramount for public health. This project aims to develop a novel photoelectrocatalysis (PEC) based bactericidal technology capable of instant inactivation and rapid decomposition of waterborne pathogens in recycled water. The PEC processes at the illuminated semiconductor photoanodes with ultraviolet (UV) and visible light activities will be innovatively utilised with the ai ....Photoelectrocatalysis-based Techniques for Bactericidal Applications. Effective control of the quality of water supply is paramount for public health. This project aims to develop a novel photoelectrocatalysis (PEC) based bactericidal technology capable of instant inactivation and rapid decomposition of waterborne pathogens in recycled water. The PEC processes at the illuminated semiconductor photoanodes with ultraviolet (UV) and visible light activities will be innovatively utilised with the aim of in-situ generation of stable di-halide radical anions, reactive oxygen species and photoholes as effectual bactericides to achieve instant inactivation and rapid decomposition of waterborne pathogens. The success of the project is expected to provide Australian water industry with enabling technology to safeguard recycled water usage.Read moreRead less