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Understanding the role of a newly recognised retrovirus in the induction of cancer and immunosuppressive disease in koalas. Leukaemia, lymphoma and opportunistic infections are major causes of mortality in both captive and wild koala populations. It is our hypothesis that a recently discovered retrovirus is responsible for these disease syndromes. Using a multidisciplinary approach, this project will determine viral parameters that correlate with the disease status of koalas and lead to improvem ....Understanding the role of a newly recognised retrovirus in the induction of cancer and immunosuppressive disease in koalas. Leukaemia, lymphoma and opportunistic infections are major causes of mortality in both captive and wild koala populations. It is our hypothesis that a recently discovered retrovirus is responsible for these disease syndromes. Using a multidisciplinary approach, this project will determine viral parameters that correlate with the disease status of koalas and lead to improvements in diagnosis and management of disease in koala populations. The planned research will also provide some insight into cross-species transmission of retroviruses.Read moreRead less
Detection of imported exotic strains of West Nile virus for national biosecurity surveillance. West Nile virus (WNV) is transmitted by mosquitoes and causes a fatal disease of the brain in animals and humans. WNV is currently exotic to this country, however a closely related, but benign cousin of this virus (Kunjin) can be found in Northern Australia. Currently it is very difficult to differentiate between infections with WNV and Kunjin using standard laboratory tests, therefore it will be diff ....Detection of imported exotic strains of West Nile virus for national biosecurity surveillance. West Nile virus (WNV) is transmitted by mosquitoes and causes a fatal disease of the brain in animals and humans. WNV is currently exotic to this country, however a closely related, but benign cousin of this virus (Kunjin) can be found in Northern Australia. Currently it is very difficult to differentiate between infections with WNV and Kunjin using standard laboratory tests, therefore it will be difficult for public health officials to detect WNV if it is introduced to Australia. In this project we aim to develop more accurate laboratory tests to detect infections with the deadly, exotic WNV using new strategies. Read moreRead less