A new tool for comprehensive label-free micro-imaging of cancer in situ. This project aims to engineer a new micro-imaging tool for comprehensive characterisation of the tumour microenvironment in situ, including micro-morphology, microvasculature, extracellular matrix, local stiffness and the functional variables of pH, oxygen content and temperature. The project will provide accessible, label-free longitudinal monitoring of tumours in animal models of disease; thereby, reducing animal use, imp ....A new tool for comprehensive label-free micro-imaging of cancer in situ. This project aims to engineer a new micro-imaging tool for comprehensive characterisation of the tumour microenvironment in situ, including micro-morphology, microvasculature, extracellular matrix, local stiffness and the functional variables of pH, oxygen content and temperature. The project will provide accessible, label-free longitudinal monitoring of tumours in animal models of disease; thereby, reducing animal use, improving experimental power, and providing better micro-scale characterisation to underpin discovery and application in cancer biology. With potential for translation to humans and commercialisation, such a tool will ultimately contribute to improved diagnosis and treatment of cancer.Read moreRead less