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Biased information processing in anxiety: Low anxiety scores, but still at risk. Information processing in anxious persons is biased if confronted with threatening stimulus materials such as words or pictures. This finding has considerable implications for our understanding of fear acquisition and maintenance and for the design of therapeutic interventions. More recent research has shown, however, that low anxious persons who employ repressive coping styles show similar biases. The present proj ....Biased information processing in anxiety: Low anxiety scores, but still at risk. Information processing in anxious persons is biased if confronted with threatening stimulus materials such as words or pictures. This finding has considerable implications for our understanding of fear acquisition and maintenance and for the design of therapeutic interventions. More recent research has shown, however, that low anxious persons who employ repressive coping styles show similar biases. The present project will follow up on these findings by combining the expertises of the two CIs in contemporary cognitive and psychophysiological research. It will not only provide new insights, but also offer research opportunities for postgraduate students, and prospects for future collaborative funding.Read moreRead less
Epigenetic integration of genomic and environmental information in honey bees. Environmental factors such as nutrition, drugs or childhood neglect alter gene activity without a change to the DNA code and may result in a range of conditions such as cancer, obesity and mental illness. Such epigenetic phenomena are driven by subtle and poorly understood modifications of the genome known as DNA methylation. Our aim is to study the link between DNA methylation and environmental influences. We aspire ....Epigenetic integration of genomic and environmental information in honey bees. Environmental factors such as nutrition, drugs or childhood neglect alter gene activity without a change to the DNA code and may result in a range of conditions such as cancer, obesity and mental illness. Such epigenetic phenomena are driven by subtle and poorly understood modifications of the genome known as DNA methylation. Our aim is to study the link between DNA methylation and environmental influences. We aspire to understand how environmental signals trigger the reprogramming of transcriptional control of genetic networks that lead to contrasting phenotypic and behavioural outcomes using the honey bee modelRead moreRead less
Human learning of likes and dislikes: A test of the dual process account and an investigation of its neural substrates. Dual process accounts of human affective learning hold that affective learning, the learning of likes and dislikes, and relational learning, the learning of predictive relationships, reflect separate learning mechanisms. Affective learning, for instance, is said not to extinguish, a claim that has far reaching consequences for the design of behaviourally based treatments of a ....Human learning of likes and dislikes: A test of the dual process account and an investigation of its neural substrates. Dual process accounts of human affective learning hold that affective learning, the learning of likes and dislikes, and relational learning, the learning of predictive relationships, reflect separate learning mechanisms. Affective learning, for instance, is said not to extinguish, a claim that has far reaching consequences for the design of behaviourally based treatments of anxiety. The project will test this and other predictions of dual process accounts. Moreover, it will extent the experimental analysis of affective learning to the acquisition of likes and identify the cortical bases for aversive, appetitive, and relational learning using event related functional magnetic resonance imaging.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100055
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
State-of-the-art upgrade to multi-transmit multi-receive technology for research dedicated 3 Tesla magnetic resonance imaging (MRI) scanner. Projects requiring the proposed infrastructure are aligned with two National Research Priorities. The research will lead to new methods for imaging and detecting soft tissue changes, identifying developmental, cognitive and degenerative disorders, and pharmacological research. The understanding of the basis of physiological, cognitive and biochemical proces ....State-of-the-art upgrade to multi-transmit multi-receive technology for research dedicated 3 Tesla magnetic resonance imaging (MRI) scanner. Projects requiring the proposed infrastructure are aligned with two National Research Priorities. The research will lead to new methods for imaging and detecting soft tissue changes, identifying developmental, cognitive and degenerative disorders, and pharmacological research. The understanding of the basis of physiological, cognitive and biochemical processes which will be facilitated by the new equipment will contribute to the priority area Promoting and Maintaining Good Health and will underpin an array of subsequent medical research. The new equipment will extend capabilities and training in signal analysis, biomedical engineering and biomedicine, contributing to the priority area Frontier technologies for Building and Transforming Australian Industries.Read moreRead less
Special Research Initiatives - Grant ID: SR0354494
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
BRAINnet:
Brain Research And Integrative Neuroscience Network. The brain is the ultimate frontier of science, and its complexity requires an integrative approach to neuroscience. This initiative will facilitate a unique integration of disciplines (biological, physical, computational) and scales of focus (single neurons to networks to whole-brain), within a high profile Network of Australian and international players. The Network will be harnessed by a centralized hub for sharing of data and tec ....BRAINnet:
Brain Research And Integrative Neuroscience Network. The brain is the ultimate frontier of science, and its complexity requires an integrative approach to neuroscience. This initiative will facilitate a unique integration of disciplines (biological, physical, computational) and scales of focus (single neurons to networks to whole-brain), within a high profile Network of Australian and international players. The Network will be harnessed by a centralized hub for sharing of data and techniques, and mentoring of early career researchers. The principal socio-economic and discovery outcomes will flow from the exceptionally strong foundations in fundamental and applied science, established collaboration, and demonstrated capacity for development and commercialization of frontier biotechnologies.Read moreRead less
Aquatic eye design: sharks and rays as models of underwater colour and luminance vision. Sharks are usually assumed to be colour blind. We have discovered that they may in fact see colour very well and that the eyes of different species are adapted to their particular lifestyles. Our research will help to raise the profile of sharks and portray them as animals with advanced sensory systems and complex visual behaviours rather than just dangerous killing machines. Studying the vision of sharks m ....Aquatic eye design: sharks and rays as models of underwater colour and luminance vision. Sharks are usually assumed to be colour blind. We have discovered that they may in fact see colour very well and that the eyes of different species are adapted to their particular lifestyles. Our research will help to raise the profile of sharks and portray them as animals with advanced sensory systems and complex visual behaviours rather than just dangerous killing machines. Studying the vision of sharks may also help to reduce the number (currently >50,000) that are killed each year as bycatch by Australian long-line fisheries and make a valuable contribution to one of Australia's National Research Priorities (an Environmentally Sustainable Australia) for managing and conserving our biodiversity.Read moreRead less
To be cooperative or selfish: individual decisions in a model society. Understanding the basis of cooperative behaviour is a major challenge to biological and social science. Our ability to deal with problems such as global warming and the rapid loss of biodiversity, will depend upon an unprecedented level of cooperation between individuals and countries. Our work will use an animal model that shares a number of key characteristics with the societies of our early human ancestors to explore, thro ....To be cooperative or selfish: individual decisions in a model society. Understanding the basis of cooperative behaviour is a major challenge to biological and social science. Our ability to deal with problems such as global warming and the rapid loss of biodiversity, will depend upon an unprecedented level of cooperation between individuals and countries. Our work will use an animal model that shares a number of key characteristics with the societies of our early human ancestors to explore, through experiments and detailed molecular analysis, the basis of cooperative interactions between individuals. This work will uncover the key principles that drive the evolution of cooperation in society and will help us to understand the basis of one the most important components of human nature.Read moreRead less
Maturation of the brain and the development of cognitive abilities. This project aims to develop techniques for measuring the growing brain. We will use these techniques to determine how the growing brain influences a child's intellectual ability and to answer an important question - do areas of the brain mature at the same or different rates and what influence does that have on the development of specific abilities such as language and reasoning? An answer to this question will make an import ....Maturation of the brain and the development of cognitive abilities. This project aims to develop techniques for measuring the growing brain. We will use these techniques to determine how the growing brain influences a child's intellectual ability and to answer an important question - do areas of the brain mature at the same or different rates and what influence does that have on the development of specific abilities such as language and reasoning? An answer to this question will make an important contribution to our theoretical understanding of developmental disorders. Moreover, given the influence of intellectual development on life prospects, it is important to understand how early brain development impacts on a child's ability to learn.Read moreRead less
Learning and memory in the honeybee: Task-dependent brain development. We wish to explore whether the development of specific brain regions in young bees depends upon the nature of the learning task in which they are engaged. We will examine tasks that involve two sensory modalities: olfaction and vision, both of which are important to successful foraging. The relative ease with which bees can be trained, and their nervous systems accessed, make them a very attractive subject in which to study f ....Learning and memory in the honeybee: Task-dependent brain development. We wish to explore whether the development of specific brain regions in young bees depends upon the nature of the learning task in which they are engaged. We will examine tasks that involve two sensory modalities: olfaction and vision, both of which are important to successful foraging. The relative ease with which bees can be trained, and their nervous systems accessed, make them a very attractive subject in which to study fundamental principles of learning and memory that may span a variety of organisms.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453073
Funder
Australian Research Council
Funding Amount
$129,485.00
Summary
Establishment of a South Australian rTMS Facility. It is proposed to establish a South Australian Facility for rapid rate transcranial magnetic stimulation (TMS) which will be the only one in Australia. This Facility will provide enormous opportunities for collaborative cutting edge investigations into the role of the human cortical areas in a diverse range of tasks. For example, projects have been identified projects employing rTMS to study sensorimotor cortical plasticity, facilitate functiona ....Establishment of a South Australian rTMS Facility. It is proposed to establish a South Australian Facility for rapid rate transcranial magnetic stimulation (TMS) which will be the only one in Australia. This Facility will provide enormous opportunities for collaborative cutting edge investigations into the role of the human cortical areas in a diverse range of tasks. For example, projects have been identified projects employing rTMS to study sensorimotor cortical plasticity, facilitate functional recovery following stroke and investigate the mechanisms of savant behaviour. Provision of this Facility will provide further support for this productive and internationally renowned group of scientists to develop their research programs.Read moreRead less