Molecular basis of rust infection and host plant resistance. Plant diseases threaten agricultural productivity in Australia, with rust fungi being a major problem for cereal grain production. This project will investigate molecular processes underlying the infection of plants by rust fungi and will provide basic knowledge for development of novel and durable disease resistance strategies.
Cereals and rusts: molecular interactions for plant defence, food security. This project aims to discover the fundamental molecular interactions between proteases and protease inhibitors that occur in the ongoing conflict between cereals and their rust fungal pathogens. The research combines plant pathology, genomics and functional proteomics, and is enabled by a rapidly developing experimental approach known as activity-based protein profiling. The knowledge and outcomes potentially benefit pl ....Cereals and rusts: molecular interactions for plant defence, food security. This project aims to discover the fundamental molecular interactions between proteases and protease inhibitors that occur in the ongoing conflict between cereals and their rust fungal pathogens. The research combines plant pathology, genomics and functional proteomics, and is enabled by a rapidly developing experimental approach known as activity-based protein profiling. The knowledge and outcomes potentially benefit plant breeders through significantly improved resistance of cereals to rust diseases in Australia and overseas, thereby enhancing global food security.Read moreRead less
Translocation of secreted effector proteins from fungal pathogens into host plant cells. Every year, fungal diseases of plants cause huge losses in agricultural productivity and extensive environmental damage in Australia. Disease control in major crops, like wheat, currently relies heavily on breeding for disease resistance. However, fungal pathogens continually adapt to overcome plant defences, necessitating identification of new sources of resistance. The research in this project will eluc ....Translocation of secreted effector proteins from fungal pathogens into host plant cells. Every year, fungal diseases of plants cause huge losses in agricultural productivity and extensive environmental damage in Australia. Disease control in major crops, like wheat, currently relies heavily on breeding for disease resistance. However, fungal pathogens continually adapt to overcome plant defences, necessitating identification of new sources of resistance. The research in this project will elucidate the molecular basis of a new aspect of the establishment of plant infection by fungi, and in so doing will provide new avenues for the development of novel disease resistance strategies, with relevance in particular to devastating cereal diseases like wheat rust.Read moreRead less
Isolation and functional characterisation of a pathogen meta effector able to inhibit detection of multiple disease effectors by resistant plants. The rust fungi are a major economic threat to crop production in Australia. This project will investigate the molecular mechanism used by a rust fungus to prevent detection of multiple disease-inducing proteins by resistant plants and generate knowledge that will lead to the development of new and more effective disease control strategies.
Role of fungal secreted proteins as plant disease effectors. Many crop diseases are economically significant threats to agricultural productivity in Australia, with rust fungi in particular being a major problem for cereal grain production. Current methods of rust disease control are based on breeding for resistance but continued adaption by rust fungi to overcome plant defences means there is an urgent need for new methods of crop protection. This project will investigate molecular processes ....Role of fungal secreted proteins as plant disease effectors. Many crop diseases are economically significant threats to agricultural productivity in Australia, with rust fungi in particular being a major problem for cereal grain production. Current methods of rust disease control are based on breeding for resistance but continued adaption by rust fungi to overcome plant defences means there is an urgent need for new methods of crop protection. This project will investigate molecular processes underlying fungal infection of plants, focusing on mechanisms that enable fungi to take over the metabolism of infected cells. The research will provide basic knowledge for development of novel and durable disease resistance strategies.Read moreRead less
Regulation and expression of disease resistance responses in the Rhynchosporium secalis/barley interaction. The barley leaf scald fungus, Rhynchosporium secalis, causes annual losses of up to 10% in Australia's major export crop, barley. The primary aim of this project is to isolate and understand the interplay of genes specifically involved in the regulation of resistance to scald. Several resistance-specific genes will be functionally analysed to identify regulatory signalling pathways that li ....Regulation and expression of disease resistance responses in the Rhynchosporium secalis/barley interaction. The barley leaf scald fungus, Rhynchosporium secalis, causes annual losses of up to 10% in Australia's major export crop, barley. The primary aim of this project is to isolate and understand the interplay of genes specifically involved in the regulation of resistance to scald. Several resistance-specific genes will be functionally analysed to identify regulatory signalling pathways that link genetic expression with the specific gene-for-gene disease resistance phenotype. Knowledge of the genes controlling signalling processes within the disease-challenged plant will allow for the development of more effective and durable resistances by traditional breeding and transgenic approaches.Read moreRead less