The pharmacokinetics of plant secondary metabolites and their effects on feeding in the brushtail possum. Plant secondary metabolites (PSMs) are considered to protect against herbivory, although the mechanisms are not well understood. This project will determine how marsupial folivores avoid toxicity when browsing on Eucalyptus leaf. Blood levels of terpenes, phenols and their metabolites will be measured in the brushtail possum while it feeds on a diet of varying PSM content. We expect to be ab ....The pharmacokinetics of plant secondary metabolites and their effects on feeding in the brushtail possum. Plant secondary metabolites (PSMs) are considered to protect against herbivory, although the mechanisms are not well understood. This project will determine how marsupial folivores avoid toxicity when browsing on Eucalyptus leaf. Blood levels of terpenes, phenols and their metabolites will be measured in the brushtail possum while it feeds on a diet of varying PSM content. We expect to be able to show relationships between the ingestion and blood levels of PSMs and feeding behaviour. This will give a greater understanding of the effect of plant toxins on browsing behaviour, enabling improved foraging models and more effective habitat management.Read moreRead less