New polymers for imaging applications. Cancer and cardiovascular disease are the most devastating diseases in any developed country. This project describes improved imaging agents to improve the detection and earlier treatment of diseases whilst avoiding any problems with toxicity of imaging agents in the body.
Origami with triblock copolymers. This project aims to develop new nanoparticles structures with optimised shapes for biological applications. Most nanoparticles developed for drug delivery are spherical. However, these are not always the most efficacious as they often encounter problems penetrating the living cell. Viruses which have evolved to highly effectively invade living cells are often elongated. The project aims to mimic these structures by using the self-assembly of polymers. Expected ....Origami with triblock copolymers. This project aims to develop new nanoparticles structures with optimised shapes for biological applications. Most nanoparticles developed for drug delivery are spherical. However, these are not always the most efficacious as they often encounter problems penetrating the living cell. Viruses which have evolved to highly effectively invade living cells are often elongated. The project aims to mimic these structures by using the self-assembly of polymers. Expected outcomes include a better understanding how various sizes, shapes and surface groups of the prepared nanoparticles interact with cells. The knowledge could assist in the creation of better drug carriers for more efficient disease treatment.Read moreRead less