Pro-Fluorescent Aryl Nitroxides: New Probes for Polymer Lifetime and Kinetics Research. Internal aryl rings present in novel probes developed for this project impart fluorescence which is efficiently and internally quenched by the presence of a paramagnetic nitroxide group. Scavenging of radicals by the nitroxide however "switches on" the fluorescence and this enables powerful new fluorescence-based detection levels for the technique of nitroxide free radical scavenging. Such sensitivity is a ....Pro-Fluorescent Aryl Nitroxides: New Probes for Polymer Lifetime and Kinetics Research. Internal aryl rings present in novel probes developed for this project impart fluorescence which is efficiently and internally quenched by the presence of a paramagnetic nitroxide group. Scavenging of radicals by the nitroxide however "switches on" the fluorescence and this enables powerful new fluorescence-based detection levels for the technique of nitroxide free radical scavenging. Such sensitivity is applicable to polymerization kinetics studies, as well as providing new means for the determination of materials lifetimes. The development of pro-fluorescent markers as indicators for polymer degradation would be a significant outcome for materials where component failure has a major negative impact.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560679
Funder
Australian Research Council
Funding Amount
$932,870.00
Summary
Materials and Surface Characterisation Facility. Australian scientists are well positioned to be at the forefront of nanotechnology, biotechnology and advanced materials development. The proposed Facility, housing state-of-the-art equipment, will enable cutting-edge research in these areas by internationally renowned researchers at the University of Melbourne, Monash University, RMIT University, and CSIRO. Such research will facilitate the development of advanced materials for diverse applicatio ....Materials and Surface Characterisation Facility. Australian scientists are well positioned to be at the forefront of nanotechnology, biotechnology and advanced materials development. The proposed Facility, housing state-of-the-art equipment, will enable cutting-edge research in these areas by internationally renowned researchers at the University of Melbourne, Monash University, RMIT University, and CSIRO. Such research will facilitate the development of advanced materials for diverse applications including drug delivery, quantum computing, photonics and tissue engineering. The multi-user Facility will enable closer collaboration with researchers in academia and industry, and will be integral in training the next generation of Australian scientists in the nano- and biosciences.Read moreRead less
Orally active spider toxins: a novel paradigm for control of insect pests. Many insects and other arthropods are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by arthropods are also responsible for diseases such as dengue, Japanese encephalitis, and Ros ....Orally active spider toxins: a novel paradigm for control of insect pests. Many insects and other arthropods are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by arthropods are also responsible for diseases such as dengue, Japanese encephalitis, and Ross River fever. Unfortunately, many of these arthropod pests have developed resistance to chemical insecticides. This aim of this research program is to develop a new generation of environmentally-friendly natural products that can be used to control arthropod pests on pets, farms, and around the home and garden.Read moreRead less
Triblock Copolymeric Structures As Novel Dispersants. ICI are one of the largest producers of surface-active compounds in the world. ICI are represented in Australia by National Starch & Chemicals who have significant manufacturing and research/development sites in Sydney and Melbourne. As the fastest growing market for dispersants is SE Asia, it is our intention that if the research is successful that scale up and manufacture will occur at both the Bristish and Australian sites.
Surface engineering of oriented nano-layers for performance control. This research project will deliver knowledge on how to graft oriented, self assembled films from a surface, develop structure-property relationships at a nano-scale, develop a means to control these properties and develop characterization techniques at nano-scales. This research project, if successful, will deliver the ability to tailor the properties of a surface in a manner and over a range of properties that is not even cont ....Surface engineering of oriented nano-layers for performance control. This research project will deliver knowledge on how to graft oriented, self assembled films from a surface, develop structure-property relationships at a nano-scale, develop a means to control these properties and develop characterization techniques at nano-scales. This research project, if successful, will deliver the ability to tailor the properties of a surface in a manner and over a range of properties that is not even contemplated today.
In addition to the scientific benefits, there are also immediate commercial applications in Australia and worldwide for ophthalmic products (e.g. anti-fog and easy to clean lenses), if the balance of properties can be obtained.
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Design of Polymeric Devices for Biotechnological Applications. The research project focuses on the development of functional polymer particles for diagnostic applications. Advanced polymer chemistry will be used to synthesize devices for reliable and fast diagnostic systems. The outcome of this work will help promoting and maintaining good health in Australia by developing novel technologies and advanced materials based on polymer science.
Polymer nanoobjects functionalized by polymer brushes: preparation, organization and integration in devices. The proposed project targets the collaboration between two leading research teams. The University of Marburg is leading in the area of the preparation of nanoobjects, while the research team at CAMD (UNSW) focuses on the preparation of well-controlled polymer structures via RAFT polymerisation. The combined strength of both groups seeks to improve the properties of nanodevices by the atta ....Polymer nanoobjects functionalized by polymer brushes: preparation, organization and integration in devices. The proposed project targets the collaboration between two leading research teams. The University of Marburg is leading in the area of the preparation of nanoobjects, while the research team at CAMD (UNSW) focuses on the preparation of well-controlled polymer structures via RAFT polymerisation. The combined strength of both groups seeks to improve the properties of nanodevices by the attachment of well-defined polymer layers. We expect therefore an optimum scientific output with both groups focusing on their research potency next to being able to access new knowledge. The visit to the German research group enables the Australian researchers access to a leading team in nanotechnology.Read moreRead less
Novel Complex Architecture Polymers via a Combination of RAFT Chemistry and Pericyclic Reactions: Synthesis and Characterization. The project aims at advancing the synthetic limits and broadening the synthetic scope of living free radical polymerization and thus enhancing the library of polymer structures available for applications ranging from drug delivery to opto-electronics. Current material design for these applications is yet to reach its full potential through innovative synthetic approac ....Novel Complex Architecture Polymers via a Combination of RAFT Chemistry and Pericyclic Reactions: Synthesis and Characterization. The project aims at advancing the synthetic limits and broadening the synthetic scope of living free radical polymerization and thus enhancing the library of polymer structures available for applications ranging from drug delivery to opto-electronics. Current material design for these applications is yet to reach its full potential through innovative synthetic approaches. The proposal critically underpins and further advances Australia's leading position in both breakthrough science as well as advanced materials. Due to its significant scientific breadth and large coverage of both synthetic and physical aspects of polymer science, the project also provides a significant platform for research training at both honours and PhD level.Read moreRead less
Living Free Radical Polymerization for Nano Technology Applications. The proposed linkage project centres on a series of core projects from both the Australian and German collaborators. These core projects range from the synthesis of multifunctional nano- and micro-sphere particles, block copolymer systems used as efficient vehicles for drug delivery purposes to polymer brushes for nano-wires. The collaborating teams will carry out joint research tasks in the above mentioned fields via the excha ....Living Free Radical Polymerization for Nano Technology Applications. The proposed linkage project centres on a series of core projects from both the Australian and German collaborators. These core projects range from the synthesis of multifunctional nano- and micro-sphere particles, block copolymer systems used as efficient vehicles for drug delivery purposes to polymer brushes for nano-wires. The collaborating teams will carry out joint research tasks in the above mentioned fields via the exchange of the CIs and PhD students. The project is planned for a duration of three years to ensure an in-depth approach to the proposed projects.Read moreRead less
Biodegradable Porous HEMA-Based Polymers: Innovative Strategies for the Design and Tuneable Single-Step Production of a Novel Class of Scaffolds for Tissue Engineering. This project will lead to the development of new biocompatible, biodegradable, porous materials ideally suited to many applications in tissue engineering. These new biomaterials will be relatively inexpensive to manufacture, via simple processes using non-toxic reagents. The key properties of the biomaterials will be controllable ....Biodegradable Porous HEMA-Based Polymers: Innovative Strategies for the Design and Tuneable Single-Step Production of a Novel Class of Scaffolds for Tissue Engineering. This project will lead to the development of new biocompatible, biodegradable, porous materials ideally suited to many applications in tissue engineering. These new biomaterials will be relatively inexpensive to manufacture, via simple processes using non-toxic reagents. The key properties of the biomaterials will be controllable by appropriate choice of starting materials. The availability of these new biomaterials will facilitate future developments in tissue engineering, which will ultimately lead to improved medical outcomes in areas as diverse as joint and bone repair and organ regeneration. Local manufacture of these biomaterials would also contribute to the development of the Australian biotechnology industry.Read moreRead less