Discovery Early Career Researcher Award - Grant ID: DE240100839
Funder
Australian Research Council
Funding Amount
$442,162.00
Summary
Nanoarchitectured platform technology for molecular profiling of exosomes. The aim of this project is to develop a set of cutting-edge nanotechnologies and a nanofabrication strategy to create a highly sensitive platform technology for exosome and exosomal miRNA analysis. This project aims to generate new knowledge in mesoporus nanomaterials and transudcer as well as exosome chemistry by developing nanostructure-based platform technology (device) for automated and rapid analysis. This project's ....Nanoarchitectured platform technology for molecular profiling of exosomes. The aim of this project is to develop a set of cutting-edge nanotechnologies and a nanofabrication strategy to create a highly sensitive platform technology for exosome and exosomal miRNA analysis. This project aims to generate new knowledge in mesoporus nanomaterials and transudcer as well as exosome chemistry by developing nanostructure-based platform technology (device) for automated and rapid analysis. This project's findings are expected to provide Australia with cutting-edge expertise for developing a next-generation platform technology for analysing exosomes and other relevant biomolecules, with the potential to deliver valuable intellectual property of commercial interest and economic benefit through technological advancements.Read moreRead less
Portable biosensor for rapid detection of viral contamination in food . The objective of this project is to create a miniaturised and cost-effective electrochemical biosensor device that can detect multiple pathogens, simultaneously, even at very low level of concentrations. This device will be crucial for rapidly detect pathogen contamination in food and water to monitor their safety and quality, particularly beneficial in an outbreak or natural disaster for testing these resources. In additio ....Portable biosensor for rapid detection of viral contamination in food . The objective of this project is to create a miniaturised and cost-effective electrochemical biosensor device that can detect multiple pathogens, simultaneously, even at very low level of concentrations. This device will be crucial for rapidly detect pathogen contamination in food and water to monitor their safety and quality, particularly beneficial in an outbreak or natural disaster for testing these resources. In addition to food and water, the successful development of this versatile cost-effective sensor will benefit a wide range of companies such as pharmaceuticals, medical device manufacturing and farms for controlling product quality where detection of life threatening pathogens is pivotal to prevent risk for consumers.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100593
Funder
Australian Research Council
Funding Amount
$465,237.00
Summary
Membrane-based real-time ammonia monitoring system for sewage treatment. This project aims to develop a real-time, calibration-free, low-maintenance ammoniacal nitrogen monitoring system to assist in optimised wastewater treatment control. This project expects to generate new knowledge in the area of sensing technology using a self-developed membrane-based analytical principle, which overcomes the challenge of directly and accurately determining ammonia in a harsh wastewater environment. Expecte ....Membrane-based real-time ammonia monitoring system for sewage treatment. This project aims to develop a real-time, calibration-free, low-maintenance ammoniacal nitrogen monitoring system to assist in optimised wastewater treatment control. This project expects to generate new knowledge in the area of sensing technology using a self-developed membrane-based analytical principle, which overcomes the challenge of directly and accurately determining ammonia in a harsh wastewater environment. Expected outcomes include new theories in membrane-based sensing techniques and a market-ready field-based ammonia analytical system. This should provide significant benefits, such as a new technology for optimising wastewater treatment and reducing emissions and a valuable analytical tool to safeguard effluent quality.Read moreRead less
High specificity nanosensors for glycobiology . This project aims to develop high specificity glycosensors for identifying and characterising carbohydrates. These glycosensors are expected to generate detailed information on carbohydrate stereochemical structure and how this controls protein-carbohydrate binding and other interactions fundamental to biochemical processes. This innovative nanotechnology aims to deliver a new capability for understanding cellular recognition and antigen binding me ....High specificity nanosensors for glycobiology . This project aims to develop high specificity glycosensors for identifying and characterising carbohydrates. These glycosensors are expected to generate detailed information on carbohydrate stereochemical structure and how this controls protein-carbohydrate binding and other interactions fundamental to biochemical processes. This innovative nanotechnology aims to deliver a new capability for understanding cellular recognition and antigen binding mechanisms. The expected outcomes are new tools for glycobiology and research into carbohydrate structure-function relationships, strengthening Australia’s global reputation in nanosensors with an incisive analytical technology for biomedical sciences and the many industries utilising carbohydrates.Read moreRead less
Rational design of array-based nanozyme sensors. The project aims to obtain a deep understanding of molecular interactions at the nano-bio interface, and use this knowledge to develop a robust sensor technology for the rapid detection of foodborne pathogens in complex samples. The project proposes to employ an innovative approach that mimics the senses of smell and taste, where an array of aptamers are expected to work in synergy to precisely identify a target, providing an edge over current sen ....Rational design of array-based nanozyme sensors. The project aims to obtain a deep understanding of molecular interactions at the nano-bio interface, and use this knowledge to develop a robust sensor technology for the rapid detection of foodborne pathogens in complex samples. The project proposes to employ an innovative approach that mimics the senses of smell and taste, where an array of aptamers are expected to work in synergy to precisely identify a target, providing an edge over current sensing technologies. Expected outcomes include a ready-to-go analytical tool for the detection of food contaminants. This should provide significant economic, health, and social benefits through supporting Australian food and health sectors, and the potential commercialisation of sensor technologies.Read moreRead less
Super-Resolution Nanothermometry on Live Cells. This project aims to deliver new temperature sensors and advance the field of nanothermometry beyond its optical diffraction limit and current reliability issues. The project expects to forge a new way to study organelle metabolism and functional interactions by creating a super-resolution heat map of living cells. Expected outcomes include new knowledge of ionic energy transfer among lanthanide ions, innovative super-resolution imaging nanothermom ....Super-Resolution Nanothermometry on Live Cells. This project aims to deliver new temperature sensors and advance the field of nanothermometry beyond its optical diffraction limit and current reliability issues. The project expects to forge a new way to study organelle metabolism and functional interactions by creating a super-resolution heat map of living cells. Expected outcomes include new knowledge of ionic energy transfer among lanthanide ions, innovative super-resolution imaging nanothermometers, new biochemistry and cell biology protocols, and spectroscopy and microscopy instruments. The adoption of these outcomes in new technologies should provide significant benefits in cell biology research, life sciences, engineering sciences and Australia’s imaging and sensor industries.Read moreRead less