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Discovery Early Career Researcher Award - Grant ID: DE180100471
Funder
Australian Research Council
Funding Amount
$354,171.00
Summary
Expecting the worst: psychosocial contributors to the nocebo effect. This project aims to propose and test a new model of the nocebo effect, a powerful psychological phenomenon in which negative expectations are thought to cause unpleasant or harmful side effects following an inert treatment. Nocebo effects can lead to treatment non-adherence, unnecessary GP visits, reduced quality of life, and increased health costs. Understanding how nocebo effects are formed will assist in the development of ....Expecting the worst: psychosocial contributors to the nocebo effect. This project aims to propose and test a new model of the nocebo effect, a powerful psychological phenomenon in which negative expectations are thought to cause unpleasant or harmful side effects following an inert treatment. Nocebo effects can lead to treatment non-adherence, unnecessary GP visits, reduced quality of life, and increased health costs. Understanding how nocebo effects are formed will assist in the development of strategies to minimise their occurrence with will benefit both individuals and the health system.Read moreRead less
RCTs on Trial: How Placebo Effects Could Undermine Double-blind RCTs. Double-blind randomised placebo-controlled trials (RCTs) are considered the gold standard for establishing treatment efficacy. However, there are both theoretical and empirical reasons to believe that they do not adequately control for the placebo effect. Cost and ethical considerations prevent researchers conducting actual double-blind RCTs with patients from exploring these issues. To address this gap, this project uses nove ....RCTs on Trial: How Placebo Effects Could Undermine Double-blind RCTs. Double-blind randomised placebo-controlled trials (RCTs) are considered the gold standard for establishing treatment efficacy. However, there are both theoretical and empirical reasons to believe that they do not adequately control for the placebo effect. Cost and ethical considerations prevent researchers conducting actual double-blind RCTs with patients from exploring these issues. To address this gap, this project uses novel experimental models to systematically test key aspects of the double-blind RCT methodology that are intended to control for the placebo effect. The project aims to provide essential data on the validity of these trials, thereby improving Australia's health and ensuring that Government treatment subsidies are well spent.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100177
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
A flexible high throughput analytical system for psychopharmacology and drug discovery. A sensitive new liquid chromatography mass spectrometer will enable a team of leading researchers to detect drugs of abuse and therapeutic drugs in the brain and body as well as levels of hormones, peptides and neurotransmitters. This will enhance a large number of projects examining new treatments for addictive disorders and mental illness.
The role of threat expectancy and attentional bias modification in promoting attentional capture and disengagement in acute experimental pain. This study will test the effectiveness of a number of variants of a promising new treatment in changing responses to an experimental pain task, the cold pressor. The aim is to develop a novel treatment, with preliminary evidence for its efficacy, that can be tested as a treatment for the prevention and treatment of chronic pain.
Who may judge a book by its cover? This project aims to build a model of how and why people vary in their impressions of others and in the accuracy of these impressions. People readily form impressions of others from their faces and these impressions influence crucial decisions: election results, court case outcomes and partner choices. To build this model, the project will apply twin data and construct a psychometric test to measure variation in facial impressions. The research is expected to l ....Who may judge a book by its cover? This project aims to build a model of how and why people vary in their impressions of others and in the accuracy of these impressions. People readily form impressions of others from their faces and these impressions influence crucial decisions: election results, court case outcomes and partner choices. To build this model, the project will apply twin data and construct a psychometric test to measure variation in facial impressions. The research is expected to lead to insights into this aspect of social perception, and to identify the sources of atypical or inaccurate facial judgements. This has applications in health contexts (to identify social impairment) and in security contexts (for personnel selection).Read moreRead less
A social cure: how multiple social groups are key to health and wellbeing. Building on the increased recognition that social factors affect both mental and physical health, the research will examine how and when social identities and group membership determine wellbeing. The work is at the forefront of current societal concerns relating to coping with social disadvantage and life-transitions.
The regulation of desire by bodily state. Many experiences, like food, wine and sex, are pleasurable. These experiences are also desired, but less so when sated. The aim of this proposal is to understand how satiation regulates desire. We propose two memory-based models, and test them using several new experimental approaches. This is significant, not only because poorly regulated desire is linked to many social and economic ills (e.g., over-eating), but also because it is a key part of huma ....The regulation of desire by bodily state. Many experiences, like food, wine and sex, are pleasurable. These experiences are also desired, but less so when sated. The aim of this proposal is to understand how satiation regulates desire. We propose two memory-based models, and test them using several new experimental approaches. This is significant, not only because poorly regulated desire is linked to many social and economic ills (e.g., over-eating), but also because it is a key part of human motivation that is poorly understood. The expected outcome is a new theoretical model of how memory processes interact with bodily signals to generate both sated states and desire. The benefits include a new understanding of how desire is regulated and how and why this might break down.Read moreRead less
Enhancing outcomes for separated families by improving family mediation. More than 100,000 adults and 60,000 children experience family breakdown each year in Australia, which wreaks enormous personal, social, and economic costs. This project aims to develop more effective ways to mediate disputes over shared parenting after family breakdown.
To focus on pain or not to focus: WHEN is the question. The experience of pain is a ubiquitous experience, and persistent pain is common and causes enormous personal and
societal burden. Anyone who has been in severe pain will understand that pain captures attention, but the role that attention plays in
increasing pain perception is poorly understood. This project will test a new conceptual model that calls for a change in the paradigm underlying research into attention and pain. We will use nov ....To focus on pain or not to focus: WHEN is the question. The experience of pain is a ubiquitous experience, and persistent pain is common and causes enormous personal and
societal burden. Anyone who has been in severe pain will understand that pain captures attention, but the role that attention plays in
increasing pain perception is poorly understood. This project will test a new conceptual model that calls for a change in the paradigm underlying research into attention and pain. We will use novel experimental tasks in virtual reality environments to address
these important gaps in our knowledge. The project will significantly advance our fundamental understanding of
the role of attention in pain perception and pave the way for translational research to reduce the substantial burden pain causes.Read moreRead less
Breaking the cycle of homelessness: an identity change approach to enhance resilience and well-being. This project will explore the factors that contribute to the development of well-being and resilience among those who are homeless. We focus on the importance of social connections in enhancing resilience, well-being and breaking the cycle of homelessness. Findings will inform best practice guidelines and policy in emergency accommodation centres.