Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100235
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Interfacial mapping facility. New electronic materials and devices impact on everyday life in areas such as photovoltaics, biotechnology and healthcare. This facility will provide researchers with the unique capability of mapping both the structure and electronic properties of materials on the nanoscale. It will be an essential tool for developing new electronics based on nanotechnology.
Engineered nanoporous materials and composites having hierarchical structures by emulsion templating. The project aims to develop new and flexible emulsion-templated processes capable of constructing novel nanoporous materials with hierarchical structures. The project has the potential to revolutionise current approaches for making porous materials, and the outcomes will enhance Australia's ability in frontier technologies and advanced materials.
Hybrid resonant acoustics for microfluidic materials synthesis. This project aims to demonstrate the feasibility of a new class of sound waves as a microfluidic micronisation platform for high throughput particle synthesis and crystallisation of active pharmaceutical ingredients.It will use theoretical and numerical studies to research the fundamental physics of a hybrid between bulk and surface waves. This platform is expected to improve energy efficiency a thousandfold, providing an economical ....Hybrid resonant acoustics for microfluidic materials synthesis. This project aims to demonstrate the feasibility of a new class of sound waves as a microfluidic micronisation platform for high throughput particle synthesis and crystallisation of active pharmaceutical ingredients.It will use theoretical and numerical studies to research the fundamental physics of a hybrid between bulk and surface waves. This platform is expected to improve energy efficiency a thousandfold, providing an economical and environmental alternative to conventional processes such as spray drying, and potentially transforming practice across the pharmaceutical, food and other industries.Read moreRead less
Granular dynamics: characterization, modelling and application. Storage and transport of bulk solids are widely encountered in mineral, metallurgical and chemical industrials which are important to Australia. The design and control of bulk solids handling equipment must be optimised for the efficiency of processing. This project provides a systematic investigation of the techniques used to characterize bulk solids, and applies the new findings to hopper flow and pneumatic conveying. This, togeth ....Granular dynamics: characterization, modelling and application. Storage and transport of bulk solids are widely encountered in mineral, metallurgical and chemical industrials which are important to Australia. The design and control of bulk solids handling equipment must be optimised for the efficiency of processing. This project provides a systematic investigation of the techniques used to characterize bulk solids, and applies the new findings to hopper flow and pneumatic conveying. This, together with the research training offered through the conduct of the work, is very helpful to maintaining Australia’s leading position in bulk solids handling and application in resource, energy, process and allied industries.Read moreRead less
Enabling aerosol delivery of phages to defeat antibiotic-resistant bacteria. This project aims to explore the use of bacteriophages towards producing a safe, natural, and highly effective alternative to traditional antibiotics. Respiratory infections caused by multidrug-resistant Gram-negative bacteria are a major health problem worldwide, and cost Australia over $150 million annually. Some 5,000 Australians die each year from antibiotic resistant infections. The project aims to produce efficac ....Enabling aerosol delivery of phages to defeat antibiotic-resistant bacteria. This project aims to explore the use of bacteriophages towards producing a safe, natural, and highly effective alternative to traditional antibiotics. Respiratory infections caused by multidrug-resistant Gram-negative bacteria are a major health problem worldwide, and cost Australia over $150 million annually. Some 5,000 Australians die each year from antibiotic resistant infections. The project aims to produce efficacious and stable formulations of bacteriophages for easy delivery by inhalation as aerosols with a long shelf-life, making them a commercially viable product. The expected research outcome can lead to an economic and efficient technology to produce phage powders for novel treatment strategies of infections by inhalation.Read moreRead less
A New Platform of Bio-inspired Nanoparticles for Enhanced Cellular Delivery. Delivery of various molecules into cells is crucial in modern medicine. Compared to viral vectors, non-viral vectors are safer delivery vehicles, but their delivery efficiency must be improved before they can be broadly used. Inspired by the surface topography of viruses with high infectivity, this project aims to provide a fundamental understanding of the impact of surface roughness on cellular delivery efficiency; and ....A New Platform of Bio-inspired Nanoparticles for Enhanced Cellular Delivery. Delivery of various molecules into cells is crucial in modern medicine. Compared to viral vectors, non-viral vectors are safer delivery vehicles, but their delivery efficiency must be improved before they can be broadly used. Inspired by the surface topography of viruses with high infectivity, this project aims to provide a fundamental understanding of the impact of surface roughness on cellular delivery efficiency; and to use this knowledge in the designed synthesis of a new family of bio-inspired non-viral nanoparticles with both safety and high cellular delivery efficiency. The new and high performance nano-carriers will become a platform technology with broad bio-applications in gene therapy, cancer therapy and bio-imaging.Read moreRead less
Experimentally validated theory for the mixing of granular materials. The project aims to develop better mixing theories to support industrial applications. Effective mixing of granular materials such as aggregates in building industry and stockpiles in mineral processing is important for creating homogeneous products, yet industrial mixers lack scientific design and operate with no control of mixture quality. The project aims to establish a new general continuum mixing theory, which will be val ....Experimentally validated theory for the mixing of granular materials. The project aims to develop better mixing theories to support industrial applications. Effective mixing of granular materials such as aggregates in building industry and stockpiles in mineral processing is important for creating homogeneous products, yet industrial mixers lack scientific design and operate with no control of mixture quality. The project aims to establish a new general continuum mixing theory, which will be validated against X-ray measurements of grain motions within small mixers. By describing the theory using an accurate computational method, the simulations of these mixers will be scalable, and would help deliver predictions for particle mixing in much larger operations. Other expected outcomes are to control mixture quality and reduce industry reliance on costly and time-consuming trial-and-error experiments.Read moreRead less
Synergetic combination of localised internal magnesium diffusion process with cold compaction technique for fabrication of magnesium diboride (MgB2) superconductor wires. This project seeks major advancements in magnesium diboride (MgB2) superconductor performance through the development of novel techniques for the fabrication of MgB2 wire. Further improvement in MgB2 wire performance holds the key to a number of significant commercial applications, including Magnetic Resonance Imaging, fault cu ....Synergetic combination of localised internal magnesium diffusion process with cold compaction technique for fabrication of magnesium diboride (MgB2) superconductor wires. This project seeks major advancements in magnesium diboride (MgB2) superconductor performance through the development of novel techniques for the fabrication of MgB2 wire. Further improvement in MgB2 wire performance holds the key to a number of significant commercial applications, including Magnetic Resonance Imaging, fault current limiters and wind turbines.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100174
Funder
Australian Research Council
Funding Amount
$193,000.00
Summary
Acoustic levitation facility for high pressure multiphase systems research. This project aims to create a specialised acoustic levitation facility that delivers precise control of a suspended particle/droplet/bubble within a high pressure continuous phase, and simultaneous measurement of multiple bulk and interfacial properties. Acoustic levitation enables container-less experiments, offering opportunities for applied engineering and fundamental science. This acoustic levitation system will be i ....Acoustic levitation facility for high pressure multiphase systems research. This project aims to create a specialised acoustic levitation facility that delivers precise control of a suspended particle/droplet/bubble within a high pressure continuous phase, and simultaneous measurement of multiple bulk and interfacial properties. Acoustic levitation enables container-less experiments, offering opportunities for applied engineering and fundamental science. This acoustic levitation system will be integrated with a specialised Raman imaging microscope to study crystallisation, mass transfer and molecular exchange, in application areas including energy transport, carbon capture and storage, and protein nucleation. This project is expected to open new avenues in engineering, chemistry and physics.Read moreRead less
The role of electrostatic charge in airway deposition of aerosols. This project aims to unravel the importance of electrostatic charge in controlling deposition of aerosols in the respiratory tract. The expected outcome is a validated mathematical model for accurately predicting deposition behaviour of charged aerosol particles in human airways. Findings may ultimately be used to underpin novel prevention measures to reduce lung deposition of inhaled hazardous airborne particles to significantly ....The role of electrostatic charge in airway deposition of aerosols. This project aims to unravel the importance of electrostatic charge in controlling deposition of aerosols in the respiratory tract. The expected outcome is a validated mathematical model for accurately predicting deposition behaviour of charged aerosol particles in human airways. Findings may ultimately be used to underpin novel prevention measures to reduce lung deposition of inhaled hazardous airborne particles to significantly reduce health risks and costs. They may also be used to enable the development of new inhalation technologies based on electrostatic charge to improve aerosol drug delivery to the lungs of patients with respiratory diseases.Read moreRead less