Unravelling the mechanics of particle deposition at the micro-scale. This project aims to discover the mechanisms responsible for the interactions between aerosol particles and surfaces in a range of air flow conditions. The project expects to transform our understanding of particle deposition through a combination of novel laser-based diagnostic techniques, optical coherence tomography, and state of the art particle formulation methodologies. Expected outcomes of the project include delivery of ....Unravelling the mechanics of particle deposition at the micro-scale. This project aims to discover the mechanisms responsible for the interactions between aerosol particles and surfaces in a range of air flow conditions. The project expects to transform our understanding of particle deposition through a combination of novel laser-based diagnostic techniques, optical coherence tomography, and state of the art particle formulation methodologies. Expected outcomes of the project include delivery of new methods to optimise particle deposition, development of tunable powder formulations, as well as definition of particle-surface interaction mechanisms in flows. The project should provide significant benefits to particle systems for applications ranging from additive manufacturing to aerosol delivery.Read moreRead less
Dynamic input adjustment to improve the stability of transient swirling flows in spray dryers. This project will use leading-edge numerical techniques to advance the science of flow stabilisation using dynamic flow modulation techniques. Improved sustainable processing will be enabled using this flow modulation in spray dryers to reduce processing problems due to the depositon of particles on dryer walls.
A novel approach for the real-time measurement of aerosol surface area. This project aims to develop an innovative optical tomography technology capable of direct and real-time measurement of the surface area of airborne particles. By coupling advanced laser diagnostic tools with physiological models and in vitro characterisation techniques, this project will determine the hitherto unknown fundamental and critical relationships between the surface area of an aerosol and its dissolution when deli ....A novel approach for the real-time measurement of aerosol surface area. This project aims to develop an innovative optical tomography technology capable of direct and real-time measurement of the surface area of airborne particles. By coupling advanced laser diagnostic tools with physiological models and in vitro characterisation techniques, this project will determine the hitherto unknown fundamental and critical relationships between the surface area of an aerosol and its dissolution when delivered to a target. The Project’s outcomes will enable aerosol device manufacturers to develop and market significantly more advanced and highly specific products, thus conferring a competitive advantage.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100018
Funder
Australian Research Council
Funding Amount
$362,441.00
Summary
Engineering suspended particle sprays through controlled cavitation. This project aims to use cavitation to engineer particle size in sprays of micronised particles suspended in a propellant, and develop a physical mechanism for this process. Understanding how cavitation affects the size of agglomerates in the liquid phase and droplet size in a spray is critical to developing spray devices that require precise control over the final particle size. This will be achieved through high-resolution op ....Engineering suspended particle sprays through controlled cavitation. This project aims to use cavitation to engineer particle size in sprays of micronised particles suspended in a propellant, and develop a physical mechanism for this process. Understanding how cavitation affects the size of agglomerates in the liquid phase and droplet size in a spray is critical to developing spray devices that require precise control over the final particle size. This will be achieved through high-resolution optical imaging techniques and synchrotron X-ray diagnostics. This project is expected to provide physical insight with applications for inhaled and topical pharmaceutical sprays, and industry spray drying of food products.Read moreRead less
Particle transport in the human upper airway. This project aims to determine the fundamental mechanisms that drive particle transport in physiologically realistic human airways. Through use of novel magnetic resonance imaging and laser diagnostic techniques, the project expects to transform our ability to develop effective and validated predictive capabilities for particle transport in physiologically accurate geometries. The project outcomes are expected to enable unprecedented definition of ho ....Particle transport in the human upper airway. This project aims to determine the fundamental mechanisms that drive particle transport in physiologically realistic human airways. Through use of novel magnetic resonance imaging and laser diagnostic techniques, the project expects to transform our ability to develop effective and validated predictive capabilities for particle transport in physiologically accurate geometries. The project outcomes are expected to enable unprecedented definition of how particles are transported in human airways as a function of breathing profiles, particle properties and morphology.Read moreRead less