Powder blending for dry powder inhalers: a new approach for direct control of powder structure. Over 80 per cent of pharmaceutical products involve the processing of powders. This project will generate new knowledge of how to assemble fine and cohesive particles into the structure required for dry powder inhaler products, leading to the development of new low-cost medicines in Australia and the Asia Pacific region.
Hybrid resonant acoustics for microfluidic materials synthesis. This project aims to demonstrate the feasibility of a new class of sound waves as a microfluidic micronisation platform for high throughput particle synthesis and crystallisation of active pharmaceutical ingredients.It will use theoretical and numerical studies to research the fundamental physics of a hybrid between bulk and surface waves. This platform is expected to improve energy efficiency a thousandfold, providing an economical ....Hybrid resonant acoustics for microfluidic materials synthesis. This project aims to demonstrate the feasibility of a new class of sound waves as a microfluidic micronisation platform for high throughput particle synthesis and crystallisation of active pharmaceutical ingredients.It will use theoretical and numerical studies to research the fundamental physics of a hybrid between bulk and surface waves. This platform is expected to improve energy efficiency a thousandfold, providing an economical and environmental alternative to conventional processes such as spray drying, and potentially transforming practice across the pharmaceutical, food and other industries.Read moreRead less
Engineered nanoporous materials and composites having hierarchical structures by emulsion templating. The project aims to develop new and flexible emulsion-templated processes capable of constructing novel nanoporous materials with hierarchical structures. The project has the potential to revolutionise current approaches for making porous materials, and the outcomes will enhance Australia's ability in frontier technologies and advanced materials.
Engineered nanoporous materials and composites having hierarchical structures by emulsion templating. The project aims to develop new and flexible emulsion-templated processes capable of constructing novel nanoporous materials with hierarchical structures. The project has the potential to revolutionise current approaches for making porous materials, and the outcomes will enhance Australia's ability in frontier technologies and advanced materials.
Electrostatic formation of liquid marbles. This project aims to design complex liquid marbles by electrostasis. Liquid marbles are particle-liquid aggregates which have inspired a variety of applications, including pollution and gas sensors, actuators, microreactors and drug delivery vehicles. Until now, only an external layer of non-wettable particles could be readily incorporated. This project will broaden the achievable complexity and application of the particle-drop aggregates, add value to ....Electrostatic formation of liquid marbles. This project aims to design complex liquid marbles by electrostasis. Liquid marbles are particle-liquid aggregates which have inspired a variety of applications, including pollution and gas sensors, actuators, microreactors and drug delivery vehicles. Until now, only an external layer of non-wettable particles could be readily incorporated. This project will broaden the achievable complexity and application of the particle-drop aggregates, add value to Australia’s high-performance materials manufacturing industry, and expand knowledge in colloid and interface science and particle electrostatics. Industries including pharmaceutical and personal-care industries will benefit from low-energy, high-efficiency production of next-generation complex liquid marbles.Read moreRead less
Perfect particles: Accurate breakage predictions by 3D printing of granules. Granule breakage of micro-structured specialty products impedes manufacturing and degrades product performance. Predictive breakage models have had limited success as each granule has a unique structure. Differences between the model predictions and experimental breakage test results could be due to inaccurate models or irreproducible experimental results due to granule structure differences. This project is expected to ....Perfect particles: Accurate breakage predictions by 3D printing of granules. Granule breakage of micro-structured specialty products impedes manufacturing and degrades product performance. Predictive breakage models have had limited success as each granule has a unique structure. Differences between the model predictions and experimental breakage test results could be due to inaccurate models or irreproducible experimental results due to granule structure differences. This project is expected to be the first ever application of three-dimensional printing for reproducible breakage testing. The project aims to: create the first ever multiple identical copies of complex granules using polyjet three-dimensional printing; model and experimentally measure granule breakage; and develop sophisticated Digital Elevation Models of granule breakage for practical use in industry.Read moreRead less
Electrostatic formation of liquid marbles. This project aims to design complex liquid marbles by electrostasis. Liquid marbles are particle-liquid aggregates which have inspired a variety of applications, including pollution and gas sensors, actuators, microreactors and drug delivery vehicles. Until now, only an external layer of non-wettable particles could be readily incorporated. This project will broaden the achievable complexity and application of the particle-drop aggregates, add value to ....Electrostatic formation of liquid marbles. This project aims to design complex liquid marbles by electrostasis. Liquid marbles are particle-liquid aggregates which have inspired a variety of applications, including pollution and gas sensors, actuators, microreactors and drug delivery vehicles. Until now, only an external layer of non-wettable particles could be readily incorporated. This project will broaden the achievable complexity and application of the particle-drop aggregates, add value to Australia’s high-performance materials manufacturing industry, and expand knowledge in colloid and interface science and particle electrostatics. Industries including pharmaceutical and personal-care industries will benefit from low-energy, high-efficiency production of next-generation complex liquid marbles.Read moreRead less
Fundamentals and applications of continuous-flow microprocessing systems based on supercritical fluids and gas expanded liquids. Microchemical systems have considerable potential in the area of chemical discovery and development. Practical application of these systems requires fundamental understanding and strategies for conversion to appropriate scale. The aim of this project is to overcome such challenges in the development of microstructured continuous-flow technology.