Powder blending for dry powder inhalers: a new approach for direct control of powder structure. Over 80 per cent of pharmaceutical products involve the processing of powders. This project will generate new knowledge of how to assemble fine and cohesive particles into the structure required for dry powder inhaler products, leading to the development of new low-cost medicines in Australia and the Asia Pacific region.
Hybrid resonant acoustics for microfluidic materials synthesis. This project aims to demonstrate the feasibility of a new class of sound waves as a microfluidic micronisation platform for high throughput particle synthesis and crystallisation of active pharmaceutical ingredients.It will use theoretical and numerical studies to research the fundamental physics of a hybrid between bulk and surface waves. This platform is expected to improve energy efficiency a thousandfold, providing an economical ....Hybrid resonant acoustics for microfluidic materials synthesis. This project aims to demonstrate the feasibility of a new class of sound waves as a microfluidic micronisation platform for high throughput particle synthesis and crystallisation of active pharmaceutical ingredients.It will use theoretical and numerical studies to research the fundamental physics of a hybrid between bulk and surface waves. This platform is expected to improve energy efficiency a thousandfold, providing an economical and environmental alternative to conventional processes such as spray drying, and potentially transforming practice across the pharmaceutical, food and other industries.Read moreRead less
Particle scale modelling and analysis of the multiphase flows in coal preparation. Australia is the world's biggest coal exporter, and black coal is Australia's largest export, with an annual value >$20 billion. Optimum design and control of the processes in coal preparation play a critical economic role in coal production. This project aims at providing substantial improvements through the application of a novel combined continuum and discrete modelling method. Specifically, the improvements ta ....Particle scale modelling and analysis of the multiphase flows in coal preparation. Australia is the world's biggest coal exporter, and black coal is Australia's largest export, with an annual value >$20 billion. Optimum design and control of the processes in coal preparation play a critical economic role in coal production. This project aims at providing substantial improvements through the application of a novel combined continuum and discrete modelling method. Specifically, the improvements targeted relate to better process and product control, a decrease in unit energy consumption and improvements in productivity, which, together with the research training offered, will further enhance Australia's leading position in global coal industry.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH140100035
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Computational Particle Technology. ARC Research Hub for Computational Particle Technology. This research hub aims to develop and apply advanced theories and mathematical models to design and optimise particulate and multiphase processes that are widely used in the minerals and metallurgical industries. This should be achieved through detailed analysis of the fundamentals governing fluid flow, heat and mass transfer at different time and length scales, facilitated by various ....ARC Research Hub for Computational Particle Technology. ARC Research Hub for Computational Particle Technology. This research hub aims to develop and apply advanced theories and mathematical models to design and optimise particulate and multiphase processes that are widely used in the minerals and metallurgical industries. This should be achieved through detailed analysis of the fundamentals governing fluid flow, heat and mass transfer at different time and length scales, facilitated by various novel research techniques. Research outcomes including theories, computer models and simulation techniques, as well as well-trained young researchers, should have a significant impact across a range of industries of vital importance to Australia’s economic and technological future, including the minerals, metallurgical, materials, chemical, energy, pharmaceutical and environment sectors.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100085
Funder
Australian Research Council
Funding Amount
$340,000.00
Summary
Soft matter and responsive materials characterisation facility. The processing of minerals, foods and pharmaceutical materials underpins the delivery of these materials to the community. The industries associated with the named areas have cost-driven demands for higher throughput and constraints imposed by water and energy conservation requirements. Technological advances in the processing of soft matter and responsive materials therefore offer a gateway to revolutionary changes in many aspects ....Soft matter and responsive materials characterisation facility. The processing of minerals, foods and pharmaceutical materials underpins the delivery of these materials to the community. The industries associated with the named areas have cost-driven demands for higher throughput and constraints imposed by water and energy conservation requirements. Technological advances in the processing of soft matter and responsive materials therefore offer a gateway to revolutionary changes in many aspects of our everyday lives. The outcomes from research addressing these classes of advanced materials will translate into improvements in Australian industries and in training the next generation of world leading Australian scientists and engineers using state-of-the-art technology.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100266
Funder
Australian Research Council
Funding Amount
$367,446.00
Summary
Granular interfaces for sustainable processing of raw materials. This project aims to develop an innovative interface model and a comprehensive understanding of the interfacial behaviours between granular materials using advanced numerical, experimental and theoretical approaches. This project expects to generate new knowledge of mixing and segregation in particle science and technology and a practical guide to applications. Expected outcomes of this project include the enhanced competitiveness ....Granular interfaces for sustainable processing of raw materials. This project aims to develop an innovative interface model and a comprehensive understanding of the interfacial behaviours between granular materials using advanced numerical, experimental and theoretical approaches. This project expects to generate new knowledge of mixing and segregation in particle science and technology and a practical guide to applications. Expected outcomes of this project include the enhanced competitiveness of Australia and energy efficiency in its important industries such as minerals, metallurgical, chemical, energy and pharmaceutical. These outcomes should provide significant benefits such as mitigated emissions and global warming in a carbon and resource constrained world.Read moreRead less
Fundamental investigation of the briquetting behaviour of iron ore fines. Handling, including transport and processing, may account for up to 60 per cent of the total delivered price of iron ore. This project will develop an integrated computer model for an improved briquetting process of ore fines with reduced operation cost and less environmental impact, leading to a more competitive and sustainable mineral industry in Australia.
Scaling-up microfluidic drying as an efficient route to manufacture uniform and functional particles as high-value products. This project aims to scale-up microfluidic spray drying and demonstrate the method as a viable option to manufacture monodisperse microparticles as bioactive carriers or microencapsulates, with better functional properties and uniformity. It aims to transform the manufacturing of high-value products for pharmaceuticals, functional foods and biotechnology applications and l ....Scaling-up microfluidic drying as an efficient route to manufacture uniform and functional particles as high-value products. This project aims to scale-up microfluidic spray drying and demonstrate the method as a viable option to manufacture monodisperse microparticles as bioactive carriers or microencapsulates, with better functional properties and uniformity. It aims to transform the manufacturing of high-value products for pharmaceuticals, functional foods and biotechnology applications and lift productivity by managing innovation for Australia’s industries.Read moreRead less
Immune-imprinting nanoparticles (iNPs). This research promises new classes of immune-imprinting, biodegradable nanoparticles (iNPs) with anti-inflammatory properties. The engineering of such particles requires fundamental understanding of their properties that enable specific cellular interactions to regulate immunity with new anti-inflammatory pathways. For pulmonary delivery, spray-dried amino acid microspheres with tailored surfaces as carriers can be generated using the innovative microfluid ....Immune-imprinting nanoparticles (iNPs). This research promises new classes of immune-imprinting, biodegradable nanoparticles (iNPs) with anti-inflammatory properties. The engineering of such particles requires fundamental understanding of their properties that enable specific cellular interactions to regulate immunity with new anti-inflammatory pathways. For pulmonary delivery, spray-dried amino acid microspheres with tailored surfaces as carriers can be generated using the innovative microfluidic drying approach. The potential applications of iNPs are wide-ranging and are not restricted to pulmonary targeting. The potential commercial implications for Australia's emerging biopharmaceutical industry are substantial.Read moreRead less
Particle-scale modelling of particle-fluid flows in gas and oil extraction. Particle-scale modelling of particle-fluid flows in gas and oil extraction. This project aims to develop a particle scale model to study the pipeline transport of petroleum fluids. It will use a combined theoretical and experimental program, involving state-of-the-art discrete element modelling and simulation techniques, to describe the complex particle-fluid flow and erosion of pipeline transport in gas and oil extracti ....Particle-scale modelling of particle-fluid flows in gas and oil extraction. Particle-scale modelling of particle-fluid flows in gas and oil extraction. This project aims to develop a particle scale model to study the pipeline transport of petroleum fluids. It will use a combined theoretical and experimental program, involving state-of-the-art discrete element modelling and simulation techniques, to describe the complex particle-fluid flow and erosion of pipeline transport in gas and oil extraction, quantify the effects of key variables, and formulate strategies for optimum process control under different conditions. The research outcomes are expected to be useful for the process control of pipeline transport in Australia’s important petroleum and energy-related industries.Read moreRead less