An attack from all angles! Multiphase particle systems that target respiratory infection. This project will result in advanced inhaled medicines for lung infection. Micron-particles will be engineered to have sustained drug release when deposited at sites of infection, yet avoid natural clearance and defence mechanisms. To study these systems, a series of characterisation, in vitro cell and in silico tools will be developed.
Scaling-up microfluidic drying as an efficient route to manufacture uniform and functional particles as high-value products. This project aims to scale-up microfluidic spray drying and demonstrate the method as a viable option to manufacture monodisperse microparticles as bioactive carriers or microencapsulates, with better functional properties and uniformity. It aims to transform the manufacturing of high-value products for pharmaceuticals, functional foods and biotechnology applications and l ....Scaling-up microfluidic drying as an efficient route to manufacture uniform and functional particles as high-value products. This project aims to scale-up microfluidic spray drying and demonstrate the method as a viable option to manufacture monodisperse microparticles as bioactive carriers or microencapsulates, with better functional properties and uniformity. It aims to transform the manufacturing of high-value products for pharmaceuticals, functional foods and biotechnology applications and lift productivity by managing innovation for Australia’s industries.Read moreRead less
Novel carbon dioxide tolerant ceramic membranes for oxygen separation to improve the viability of clean energy technology. Conventional cryogenic air separation is a major economic impediment to the deployment of these low emission technologies like Callide oxyfuel combustion. This project will lead to the discovery of a new class of oxygen selective membranes for air separation with significantly reduced cost to improve the viability of these clean energy technologies.
Data-driven modelling of complex reactive flows. Complex reactive flow is dominant in many chemicals, physical and biological processes and should be optimised online for operational efficiency and stability, yet it is hindered by the lack of reliable model techniques. The project tackles this challenge by developing a next-generation data-driven modelling approach via integrating continuum/discrete-scale fluid-particle dynamics with system/control theories, supported by lab/plant experiments. D ....Data-driven modelling of complex reactive flows. Complex reactive flow is dominant in many chemicals, physical and biological processes and should be optimised online for operational efficiency and stability, yet it is hindered by the lack of reliable model techniques. The project tackles this challenge by developing a next-generation data-driven modelling approach via integrating continuum/discrete-scale fluid-particle dynamics with system/control theories, supported by lab/plant experiments. Driven by online data, the generic approach can open up a powerful way to reliably describe the inner state of reactors and online predict operation anomalies. The outcomes can help transform a range of industries to smart manufacturing and design, which is vital to Australia's technological future.Read moreRead less
Triboelectric separation - fundamentals and practice. Triboelectric separation is a novel way to refine mineral ores without using scarce water resources, based on the familiar generation of electrostatic charge by friction. This project will provide a practical dry particle separation process, and a better understanding of a common and important problem in electrostatics.