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Nanoporous siloxane membranes for ultrasound mediated ophthalmic drug delivery. This project will develop tailored polymers for use in a novel non-invasive ocular drug delivery device which treats vision threatening conditions such as age-related macular degeneration (AMD). The outcomes of this project will enable an entirely new ocular drug delivery technology, thereby delivering significant benefit to ophthalmic healthcare.
Discovery Early Career Researcher Award - Grant ID: DE220100748
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
Mechanofluorescent Surfaces for Understanding Complex Cell Traction Forces. This project aims to develop pressure-sensing surfaces that directly quantify surface forces, focused towards measuring complex cell traction forces. Understanding cell traction forces is a crucial challenge towards developing new materials for regenerative medicine. The surfaces, consisting of fluorescent polymer brushes, are expected to provide direct information on singular and clustered cell forces, which can reveal ....Mechanofluorescent Surfaces for Understanding Complex Cell Traction Forces. This project aims to develop pressure-sensing surfaces that directly quantify surface forces, focused towards measuring complex cell traction forces. Understanding cell traction forces is a crucial challenge towards developing new materials for regenerative medicine. The surfaces, consisting of fluorescent polymer brushes, are expected to provide direct information on singular and clustered cell forces, which can reveal new insight into how cells interact together. This may provide currently missing information on how cell-surface interaction forces modulate cell growth, differentiation and tissue formation. This insight is crucial to providing the underpinning science that can position Australia at the forefront of regenerative medicine.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL170100014
Funder
Australian Research Council
Funding Amount
$3,275,680.00
Summary
Light-Induced chemical modularity: a new frontier in macromolecular design. This project aims to develop powerful light-driven chemistries for the modular construction of advanced macromolecular materials. The expected outcome is a versatile, light-based precision macromolecular synthetic technology platform, enabling critical advances in soft matter material design and synthesis, ranging from selectivity control of chemical reactions and information-coded and biomimetic light-responsive macromo ....Light-Induced chemical modularity: a new frontier in macromolecular design. This project aims to develop powerful light-driven chemistries for the modular construction of advanced macromolecular materials. The expected outcome is a versatile, light-based precision macromolecular synthetic technology platform, enabling critical advances in soft matter material design and synthesis, ranging from selectivity control of chemical reactions and information-coded and biomimetic light-responsive macromolecules to advanced functional photoresists for 3D laser lithography as well as materials that self-report structural transformations by light or are reprogrammable in their properties by photonic fields. Harnessing the power of light as a precision tool for the construction of advanced macromolecular materials will provide technology outcomes for Australian manufacturing industries from electronics to health. This includes laser-driven 3D printing technology at the nano-level, light-adaptive smart reprogrammable coatings and materials, synthetic proteins responsive to light as well as tailor-made single cell niches.Read moreRead less
High performance inks for solution based organic light emitting diodes manufacturing. This project aims to introduce an advanced solution processing and printing technique for organic light emitting diode (OLED) fabrication based on a set of innovative macromolecular chemistries. These proceed either photochemically or thermally, exploiting precision macromolecular designs of the polymer precursor materials, which contain advanced emitter systems developed by Cynora. Solution fabrication of OLED ....High performance inks for solution based organic light emitting diodes manufacturing. This project aims to introduce an advanced solution processing and printing technique for organic light emitting diode (OLED) fabrication based on a set of innovative macromolecular chemistries. These proceed either photochemically or thermally, exploiting precision macromolecular designs of the polymer precursor materials, which contain advanced emitter systems developed by Cynora. Solution fabrication of OLED is a challenging, yet ultimately powerful, process with key advantages over current vacuum processing systems, especially with regard to production flexibility, cost and OLED size. The project will provide a functioning technology platform for solution OLED fabrication.Read moreRead less
Phosphonium ionic liquids for advanced lithium energy storage systems. This project will develop, along with a leading manufacturer in the world, high performance electrolytes for lithium batteries. The technologies and expertise generated will be of importance to many niche industries in Australia in their shift towards lower carbon operations.
Discovery Early Career Researcher Award - Grant ID: DE220100511
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
Molecular-Scale Interaction of Nanomaterials with Biomembranes. This project aims to develop a holistic understanding of how nanoparticles, and nanomaterials in general, interact with cellular materials, via the cell membrane on a molecular level. To date, the precise mechanism by which nanomaterials, such as particles, colloids, and sheets, interact with cellular material is poorly understood.
This project expects to generate new, fundamental knowledge in the field, and establish a platform for ....Molecular-Scale Interaction of Nanomaterials with Biomembranes. This project aims to develop a holistic understanding of how nanoparticles, and nanomaterials in general, interact with cellular materials, via the cell membrane on a molecular level. To date, the precise mechanism by which nanomaterials, such as particles, colloids, and sheets, interact with cellular material is poorly understood.
This project expects to generate new, fundamental knowledge in the field, and establish a platform for high-resolution, in situ, molecular-scale imaging of nanoscale events at the biomembrane. This will develop a fundamental understanding of the dynamics of nanomaterial-cell interactions, and provide benefit in the development of next-generation nanomaterial-based therapeutics and diagnostic technologies.
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The crucial role of organic-inorganic interfaces in the performance of organic optoelectronic devices. Organic electronic devices such as organic light emitting diodes and organic solar cells are expected to lead to substantial benefits over conventional electronic components. However, there is increasing evidence that the interface between the organic layers and the inorganic electrodes (or active components in hybrid devices) could be sub-optimal in terms of critical properties such as electro ....The crucial role of organic-inorganic interfaces in the performance of organic optoelectronic devices. Organic electronic devices such as organic light emitting diodes and organic solar cells are expected to lead to substantial benefits over conventional electronic components. However, there is increasing evidence that the interface between the organic layers and the inorganic electrodes (or active components in hybrid devices) could be sub-optimal in terms of critical properties such as electron transfer and stability. The aim of this project is to understand the structure and properties of such interfaces and to probe their behaviour at elevated temperatures. The results will pave the way for organic electronic devices to become a commercial reality.Read moreRead less
Two dimensional conjugated polymers: a new class of functional nanomaterials. New technologies depend on the design and development of novel materials. This project will synthesise a new class of materials, namely two dimensional conjugated polymers, which have enormous potential for creating new technologies, for example in electronics and sensing.
Janus particles and nanorattles: new materials for paint technology. This project will pave the way for self cleaning paints that achieve opacity with greatly reduced titanium dioxide levels. Painted surfaces will maintain their clean and new look for longer and a clean town look will be much more readily maintained. More efficient use of titanium dioxide will reduce the need for sand mining and reduce the cost of quality paint.
Functional molecular nanomaterials. The design and construction of advanced nanomaterials is a key step in the push towards more efficient energy systems and smarter technologies. Through the strategic assembly of new classes of molecular nanomaterials, this project will lead to important fundamental advances in nanoscience and will underpin a range of new high-level technologies.