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Sequencing Periodontal Bacteria To Determine The Relationship Between Periodontits, Renal And Vascular Function Among Indigenous Australian Adults With Chronic Kidney Disease
Funder
National Health and Medical Research Council
Funding Amount
$329,644.00
Summary
Almost 20% of Indigenous Australian adults exhibit signs of kidney disease. This study will investigate the relationship between sub-gingival (below the gum) bacteria and both kidney and artery function among Indigenous Australian participants with chronic kidney disease. Using an RCT design, the proposed study will investigate whether changes in sub-gingival bacteria and concentration following conventional treatment of periodontitis align with improvements in renal and vascular function.
The Effect Of Titanium Surface Modification On The Immuno-regulation Of Osseointegration.
Funder
National Health and Medical Research Council
Funding Amount
$308,713.00
Summary
Titanium implants are an established treatment modality in both dentistry and orthopaedics. This project will determine how implant surface modification can modulate the inflammatory response and subsequent differentiation of stem cells involved in the process of integrating the implant with bone i.e. osseointegration. The identification of the molecular mechanisms involved will thus provide leads for novel ways to further to enhance the osseointegration process and improve clinical outcomes.