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Heterotrophically grown microalgae as a feed source for the Australian aquaculture industry. The Australian aquaculture industry has rapidly grown in the past decade producing premium quality, high value species, e.g. tuna and oyster. In the new millennia it is predicted that the Australia aquaculture industry will be the most profitable area within the Australian seafood industry. An integral component for the long-term sustainability of the Australian aquaculture industry is the availability o ....Heterotrophically grown microalgae as a feed source for the Australian aquaculture industry. The Australian aquaculture industry has rapidly grown in the past decade producing premium quality, high value species, e.g. tuna and oyster. In the new millennia it is predicted that the Australia aquaculture industry will be the most profitable area within the Australian seafood industry. An integral component for the long-term sustainability of the Australian aquaculture industry is the availability of top-quality microalgal concentrates, shelf-stable pastes or live feeds, which provide the nutritional requirements of aquatic species in the hatcheries. This project will develop novel microalgal production strategies that would add value to the Australian aquaculture industry.Read moreRead less
Transport phenomena in foam fractionation. Foam fractionation has a number of immediate applications in mineral and food processing but its most exciting potential is as low cost alternative for recovering and purifying high value biosurfactants. These are materials used to stabilise interfaces in living systems, and can be used as antibiotics and antiviral agents. The affinity for biosurfactants to collect at an interface suggests that foam fractionation is an ideal process to concentrate valua ....Transport phenomena in foam fractionation. Foam fractionation has a number of immediate applications in mineral and food processing but its most exciting potential is as low cost alternative for recovering and purifying high value biosurfactants. These are materials used to stabilise interfaces in living systems, and can be used as antibiotics and antiviral agents. The affinity for biosurfactants to collect at an interface suggests that foam fractionation is an ideal process to concentrate valuable products. Clearly, a cost-effective and reliable method of enriching streams of biosurfactants will make their use even more attractive and will engender the development of more novel biomaterials, such as pepfactants.Read moreRead less
Advanced technology for production of foreign proteins in plant cell and organ cultures. The aim of this project is to develop new technology for in vitro production of pharmaceutical proteins using plant tissue culture. Animal proteins such as antibodies are currently being produced using recombinant plant systems in bioreactors; however, transient gene expression using genetically-modified viruses has a range of potential benefits for substantially increasing foreign protein titres. Because vi ....Advanced technology for production of foreign proteins in plant cell and organ cultures. The aim of this project is to develop new technology for in vitro production of pharmaceutical proteins using plant tissue culture. Animal proteins such as antibodies are currently being produced using recombinant plant systems in bioreactors; however, transient gene expression using genetically-modified viruses has a range of potential benefits for substantially increasing foreign protein titres. Because viruses rapidly infect plant tissues and can be amplified to extremely high levels, this new method for in vitro foreign protein synthesis has considerable promise. This project will extend the existing science of plant tissue culture into new areas with commercial potential.Read moreRead less
Renewable energy from carbon dioxide: Process engineering to obtain bio-oil from algae. The Stern Report (2007)[1] has called for a CO2 REDUCTION BY MORE THAN 80% in 10-20 years to prevent profound changes in the climate over coming centuries. The proposed project will capture CO2 using algae then off-set the capital investment and on-going expenses of the CO2 capture technology by creating high value products from algae (i.e. bio-diesel, livestock feed and purified water). This process aims to ....Renewable energy from carbon dioxide: Process engineering to obtain bio-oil from algae. The Stern Report (2007)[1] has called for a CO2 REDUCTION BY MORE THAN 80% in 10-20 years to prevent profound changes in the climate over coming centuries. The proposed project will capture CO2 using algae then off-set the capital investment and on-going expenses of the CO2 capture technology by creating high value products from algae (i.e. bio-diesel, livestock feed and purified water). This process aims to be independently profitable regarless of future carbon taxes or carbon trading systems. This project also investigates water purification methods and new livestock feed additives which can help reduce the effects of drought on food producers in rural and regional areas. Read moreRead less
Microfluidic device for microbial separation and concentration. This project will enhance Australia's capabilities and presence in the rapidly expanding field of chemical and biological analysis systems on a chip. We will develop and build handheld devices for microbial concentration that will facilitate earlier and easier detection of potentially pathogenic organisms in critical situations such as epidemiological crises or forensics. The portability and ease of operation of our integrated micro ....Microfluidic device for microbial separation and concentration. This project will enhance Australia's capabilities and presence in the rapidly expanding field of chemical and biological analysis systems on a chip. We will develop and build handheld devices for microbial concentration that will facilitate earlier and easier detection of potentially pathogenic organisms in critical situations such as epidemiological crises or forensics. The portability and ease of operation of our integrated microfluidic devices and their increased resilience to blockages make them ideal for use in remote areas and non-laboratory settings. Application areas will include disease detection, microbial contamination in food industries and water quality monitoring.Read moreRead less
Efficient Operation of Bioreactors using Nonlinear Dynamical Systems Theory. Current methods of determining optimal operating conditions in bioreactors have recently been shown to be inefficient, resulting in serious omissions of crucial parameter regions. We will use mathematical techniques from dynamical systems theory to establish a general framework by which bioreactor systems can be efficiently and systematically investigated to improve reactor performance. By communicating these results at ....Efficient Operation of Bioreactors using Nonlinear Dynamical Systems Theory. Current methods of determining optimal operating conditions in bioreactors have recently been shown to be inefficient, resulting in serious omissions of crucial parameter regions. We will use mathematical techniques from dynamical systems theory to establish a general framework by which bioreactor systems can be efficiently and systematically investigated to improve reactor performance. By communicating these results at relevant fora, we will increase the awareness within the Australian and international engineering communities of the advantages of modern mathematical techniques. Although this proposal focuses on bioreactors, the techniques can be easily adapted to improve the performances of other chemical processes.
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Biological Leaching of Low Grade Nickel Laterite Ores. Harnessing the capability of fungi to dissolve large quantities of nickel and cobalt from laterite ores will create a step change in the technology for processing nickel laterites and other oxide minerals. Using microorganisms and their metabolic products promises to be effective, energy saving, easily controlled and environmentally safe. The mechanistic investigation proposed in this study will generate fundamental innovations and technolo ....Biological Leaching of Low Grade Nickel Laterite Ores. Harnessing the capability of fungi to dissolve large quantities of nickel and cobalt from laterite ores will create a step change in the technology for processing nickel laterites and other oxide minerals. Using microorganisms and their metabolic products promises to be effective, energy saving, easily controlled and environmentally safe. The mechanistic investigation proposed in this study will generate fundamental innovations and technological advancement in bio-leaching of laterite ores. Such technologies can secure the sustainability of nickel production and provide unique ecological reform to the mineral extraction industry.Read moreRead less
Manipulation of Biological Particles Using Dielectrophoresis. Dielectrophoretic manipulation and separation of particles has numerous biological and medical applications, e.g. identification and characterisation of individual cells, purification of cell subpopulations from mixture suspensions, etc. This research project aims to develop a high-efficiency and low-cost DEP device for bio-particle manipulation. It will contribute significantly to the advancements in the field of biological Micro-Ele ....Manipulation of Biological Particles Using Dielectrophoresis. Dielectrophoretic manipulation and separation of particles has numerous biological and medical applications, e.g. identification and characterisation of individual cells, purification of cell subpopulations from mixture suspensions, etc. This research project aims to develop a high-efficiency and low-cost DEP device for bio-particle manipulation. It will contribute significantly to the advancements in the field of biological Micro-Electrical-Mechanical-Systems (MEMS) and nanotechnology. Industry will benefit from the expertise on micro/nano-structures and micro/nano-manufacturing achieved by this project.Read moreRead less
Developing a competitive H2 production suystem based on engineered cells of green algae. The depletion of oil reserves and the effects of global warming make the development of new, clean, sustainable fuel production systems critically important. This frontier technology has the ability to drive solar-powered hydrogen production from water. Extending the system to marine algal cells provides the possibility of coupling clean fuel production with water purification as the product of H2 combustion ....Developing a competitive H2 production suystem based on engineered cells of green algae. The depletion of oil reserves and the effects of global warming make the development of new, clean, sustainable fuel production systems critically important. This frontier technology has the ability to drive solar-powered hydrogen production from water. Extending the system to marine algal cells provides the possibility of coupling clean fuel production with water purification as the product of H2 combustion is pure water. We have already engineered green algae that produce H2 from H2O at a rate ~1000% higher than the Wild-type and through this project will incorporate further improvements with the aim of developing a competitive H2 production system.Read moreRead less
Underlying mechanisms of e-waste bioleaching and hydropyrolysis. The project will develop a reclamation technology with an ecologically sustainable solution to e-waste management. Focusing on printed circuit boards, we will use our novel bioleaching and hydropyrolysis methods to process e-wastes, recover base and precious metals and reclaim energy. This will create safe working methods, high recycling efficiencies and generation of products from e-wastes.