Testing the free radical theory of aging: do indicators of oxidative damage predict lifespan? Because of the Free Radical Theory of Aging, many millions of dollars are spent around the world on dietary antioxidants of unproven efficacy. Many millions of research dollars are spent providing support for this theory but few studies test it rigorously. The first major benefit of this research is worldwide; to refute, or to substantially enhance and focus the current support for the Free Radical Theo ....Testing the free radical theory of aging: do indicators of oxidative damage predict lifespan? Because of the Free Radical Theory of Aging, many millions of dollars are spent around the world on dietary antioxidants of unproven efficacy. Many millions of research dollars are spent providing support for this theory but few studies test it rigorously. The first major benefit of this research is worldwide; to refute, or to substantially enhance and focus the current support for the Free Radical Theory. This should help to rationalise and direct funding supplied to these areas. The second benefit is for Australia: aging is a fruitful area for research because of the high general public interest and for training because of its multidisciplinary nature, and funding in Australia is very low by international standards. Read moreRead less
Predicting climate change impacts on the biodiversity of Lord Howe Island: an approach using experimental and historical data. Climate change will have profound impacts on biodiversity. We will investigate both recent and future impacts of climate change on invertebrate and plant assemblages on Lord Howe Island, an important World Heritage Area. We will 1. compare current assemblages with a unique set of historical databases spanning the past 150 years, to investigate whether recent warming has ....Predicting climate change impacts on the biodiversity of Lord Howe Island: an approach using experimental and historical data. Climate change will have profound impacts on biodiversity. We will investigate both recent and future impacts of climate change on invertebrate and plant assemblages on Lord Howe Island, an important World Heritage Area. We will 1. compare current assemblages with a unique set of historical databases spanning the past 150 years, to investigate whether recent warming has affected community composition and 2. experimentally assess impacts of increasing temperature and CO2 on Lord Howe's unique flora and fauna. Our assessment of species vulnerability to climate change threats will be used to inform future conservation policy and species management on Lord Howe. Read moreRead less
Visualisation of latent DNA. This project aims to deliver a proof-of-concept that allows visualisation of invisible DNA (latent DNA) into a quick, inexpensive and practical DNA collection method that will lead to DNA evidence being available in more cases. It will build upon a proof-of-concept method ready for transferal to forensic casework. This will allow DNA evidence recovery technicians to improve their hit rate in recovering latent DNA from real crime items, leading to more informative DNA ....Visualisation of latent DNA. This project aims to deliver a proof-of-concept that allows visualisation of invisible DNA (latent DNA) into a quick, inexpensive and practical DNA collection method that will lead to DNA evidence being available in more cases. It will build upon a proof-of-concept method ready for transferal to forensic casework. This will allow DNA evidence recovery technicians to improve their hit rate in recovering latent DNA from real crime items, leading to more informative DNA profiles. Crime items that currently yield no genetic information will now be informative, assisting investigations of serious crimes or terrorist incidents.Read moreRead less
Special Research Initiatives - Grant ID: SR200100005
Funder
Australian Research Council
Funding Amount
$36,000,000.00
Summary
Securing Antarctica's Environmental Future. This program aims to deliver unprecedented research capability for securing Antarctic environments in the face of uncertain change.
By integrating a highly skilled team with new approaches and breakthrough technologies, the program anticipates discovery science, enhanced environmental forecasting and optimised decision-making to advance Australia’s position as an influential Antarctic nation.
Expected outcomes include better environmental management ....Securing Antarctica's Environmental Future. This program aims to deliver unprecedented research capability for securing Antarctic environments in the face of uncertain change.
By integrating a highly skilled team with new approaches and breakthrough technologies, the program anticipates discovery science, enhanced environmental forecasting and optimised decision-making to advance Australia’s position as an influential Antarctic nation.
Expected outcomes include better environmental management, unparalleled strategic decision-support for an effective Antarctic Treaty, and new minds to address Antarctica’s new challenges.
Anticipated benefits are the means to transform environmental forecasting and management in the Antarctic, for Australia, and to the advantage of global security.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561013
Funder
Australian Research Council
Funding Amount
$220,000.00
Summary
X-ray diffraction System for Protein Crystallography and Structural Biology. Knowledge of protein structures enables researchers to explain cellular function at a molecular level. In particular, it provides essential information to understand the mechanism of diseases, such as cancer or AIDS, and it ultimately leads to the design of better drugs.
An in-house X-ray protein crystallography facility will allow us to determine the structures of key proteins effectively and competitively, opening up ....X-ray diffraction System for Protein Crystallography and Structural Biology. Knowledge of protein structures enables researchers to explain cellular function at a molecular level. In particular, it provides essential information to understand the mechanism of diseases, such as cancer or AIDS, and it ultimately leads to the design of better drugs.
An in-house X-ray protein crystallography facility will allow us to determine the structures of key proteins effectively and competitively, opening up extensive possibilities for multi-disciplinary ground-breaking research.
The University research portfolio has evolved to embrace the revolution in structural biology with numerous projects and collaborations focusing on proteins involved in bacterial infections, degenerative disorders and biotechnological applications.Read moreRead less
Where will species go? Revolutionising projections of species distributions with climate change. Improving our capacity to predict climate change impacts on biodiversity is a National Research Priority and a priority under the National Biodiversity and Climate Change Action Plan (2004-2007). Our research will revolutionise the field of bioclimatic modelling by enabling the probability of losses/gains in species distributions to be calculated. This will enable policy makers to identify vulnerable ....Where will species go? Revolutionising projections of species distributions with climate change. Improving our capacity to predict climate change impacts on biodiversity is a National Research Priority and a priority under the National Biodiversity and Climate Change Action Plan (2004-2007). Our research will revolutionise the field of bioclimatic modelling by enabling the probability of losses/gains in species distributions to be calculated. This will enable policy makers to identify vulnerable species and provides a strong framework for prioritizing areas for research and monitoring. Our research will interface two disciplines, earth and biological sciences, and establish a new international collaboration that will ensure Australia is at the forefront of a rapidly developing research field. Read moreRead less
Impacts of climate change on sustainability of temperate native pasture: an experiment. The sustainable use of temperate native pastures is important economically because of grazing and for biodiversity since they are home to many threatened plants. Native pasture sustainability depends on maintaining species diversity and vegetation productivity. Climate change is likely to have major impacts on both factors. The aims of this project are to elucidate the impacts of climate change on the species ....Impacts of climate change on sustainability of temperate native pasture: an experiment. The sustainable use of temperate native pastures is important economically because of grazing and for biodiversity since they are home to many threatened plants. Native pasture sustainability depends on maintaining species diversity and vegetation productivity. Climate change is likely to have major impacts on both factors. The aims of this project are to elucidate the impacts of climate change on the species composition, productivity and nutritional quality of a grazed native pasture. This is important, as it will allow us to predict likely problems caused by global climate change and increase our understanding of the mechanisms underlying these changes.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100492
Funder
Australian Research Council
Funding Amount
$462,720.00
Summary
Robust strategies to achieve sustainable savannas under rapid global change. This project aims to design approaches for financial incentive programs that are robust to uncertainties in global climate and economic change, while delivering multiple ecosystem services. Despite billions of dollars allocated to landholders, these schemes have not been evaluated under a range of potential futures. This project expects to incorporate an unprecedented range of uncertainties into incentive program design ....Robust strategies to achieve sustainable savannas under rapid global change. This project aims to design approaches for financial incentive programs that are robust to uncertainties in global climate and economic change, while delivering multiple ecosystem services. Despite billions of dollars allocated to landholders, these schemes have not been evaluated under a range of potential futures. This project expects to incorporate an unprecedented range of uncertainties into incentive program design, and test program performance using spatial simulations of Australia’s dynamic savanna rangelands. This should lay the groundwork for applications to other environments facing similarly uncertain futures, and may prove vital to ensure we can adapt and thrive in a changing climateRead moreRead less
Adapting to climate change: does enhanced metabolism provide heritable protection against ocean acidification and increasing temperature in oysters? By the end of this century, our oceans will have much higher concentrations of carbon dioxide and will be several degrees warmer. We have developed a population of oysters that can survive in these conditions, and the project will examine these oysters at the molecular level to determine whether increased metabolism is responsible for their survival ....Adapting to climate change: does enhanced metabolism provide heritable protection against ocean acidification and increasing temperature in oysters? By the end of this century, our oceans will have much higher concentrations of carbon dioxide and will be several degrees warmer. We have developed a population of oysters that can survive in these conditions, and the project will examine these oysters at the molecular level to determine whether increased metabolism is responsible for their survival.Read moreRead less
Global climate change and the future for coral reef fishes. Australia's coral reefs are icons of immense biological, economic and cultural importance. They are also threatened by climate change. This research will address the serious lack of knowledge about the impact of climate change on coral reef fishes and integrate with other research at the ARC Centre of Excellence for Coral Reef Studies to help find innovative solutions to the problem of climate change and promote the sustainable manageme ....Global climate change and the future for coral reef fishes. Australia's coral reefs are icons of immense biological, economic and cultural importance. They are also threatened by climate change. This research will address the serious lack of knowledge about the impact of climate change on coral reef fishes and integrate with other research at the ARC Centre of Excellence for Coral Reef Studies to help find innovative solutions to the problem of climate change and promote the sustainable management of Australia's extensive coral reef ecosystems.Read moreRead less