Pharmacological modification of retinal and visual function and relation to control of refractive error. Myopia (short-sightedness) affects many hundreds of millions of people worldwide and can lead to blindness. Drug treatments that prevent myopia are being developed, however there is no efficient way of determining who is at risk of myopia or who will benefit from these treatments. This fundamental research project will determine the retinal and visual effects of pharmacologic agents that inhi ....Pharmacological modification of retinal and visual function and relation to control of refractive error. Myopia (short-sightedness) affects many hundreds of millions of people worldwide and can lead to blindness. Drug treatments that prevent myopia are being developed, however there is no efficient way of determining who is at risk of myopia or who will benefit from these treatments. This fundamental research project will determine the retinal and visual effects of pharmacologic agents that inhibit myopia, with the aim of determining an ocular measure that is related to myopia, which is altered by drugs that are known to slow myopia progression, and that could be used as an indication of an agent's likely effectiveness.Read moreRead less
Optical defects of the eye and their relationship to visual performance. All of us will need ophthalmic correction (spectacles, contact lenses and/or refractive surgery) at some stage in our lives. This research is important to the whole Australian community as it will lead to improved equipment for measuring optics of the eye and their effects on spatial vision, better techniques for measuring vision, and obtaining a better understanding of the contribution of the optics to human vision. It wil ....Optical defects of the eye and their relationship to visual performance. All of us will need ophthalmic correction (spectacles, contact lenses and/or refractive surgery) at some stage in our lives. This research is important to the whole Australian community as it will lead to improved equipment for measuring optics of the eye and their effects on spatial vision, better techniques for measuring vision, and obtaining a better understanding of the contribution of the optics to human vision. It will provide information about how correcting optical defects through customized refractive surgery and how inducing optical defects (eg with progressive addition lenses) affect vision, and will thus guide developments in refractive surgery and spectacle lenses. Read moreRead less
Improving the visibility and safety of pedestrians, roadworkers and cyclists. Pedestrian and cyclist fatalities cost Australia ~$2 billion/year, accounting for a third of road users killed or seriously injured. Late visual recognition by motorists is the main reason these collisions occur. While visibility aids to improve pedestrian and cyclist conspicuity have been advocated, they have had limited success. We will use innovative driving measurement techniques to advance understanding of pedest ....Improving the visibility and safety of pedestrians, roadworkers and cyclists. Pedestrian and cyclist fatalities cost Australia ~$2 billion/year, accounting for a third of road users killed or seriously injured. Late visual recognition by motorists is the main reason these collisions occur. While visibility aids to improve pedestrian and cyclist conspicuity have been advocated, they have had limited success. We will use innovative driving measurement techniques to advance understanding of pedestrian and cyclist visibility and the effectiveness of different visibility aids for enhancing pedestrians and cyclist recognition. We will develop novel visibility aids to maximise pedestrian and cyclist conspicuity and evidence-based educational programs to improve the safety of vulnerable road users.Read moreRead less
Peripheral aberrations of the human eye. This project will benefit Australia from several perspectives. It will make an important contribution to understanding limitations to peripheral vision of the eye, particularly as a result of refractive surgical intervention. This is important because many Australians will require such surgery. Being able to better measure and correct peripheral aberrations will lead to improved imaging of the eye and thus contribute to improved detection and diagnosis of ....Peripheral aberrations of the human eye. This project will benefit Australia from several perspectives. It will make an important contribution to understanding limitations to peripheral vision of the eye, particularly as a result of refractive surgical intervention. This is important because many Australians will require such surgery. Being able to better measure and correct peripheral aberrations will lead to improved imaging of the eye and thus contribute to improved detection and diagnosis of ophthalmic disease. The study will benefit ophthalmologists, optometrists, and engineers involved in designing visual instruments. This project will provide training in adaptive optics for graduate students not available in any other Australian institution.Read moreRead less
The kinematics of the anterior eye deformation. This project has a potential to benefit Australia from a number of perspectives. The outcomes will provide ophthalmologists and optometrists with currently unavailable knowledge on dynamic behaviour of eye. In particular the research will identify aspects of corneal deformation that in turn will help improve the accuracy of refractive surgeries and aid in the management of glaucoma. Also, the knowledge generated through this project will be of valu ....The kinematics of the anterior eye deformation. This project has a potential to benefit Australia from a number of perspectives. The outcomes will provide ophthalmologists and optometrists with currently unavailable knowledge on dynamic behaviour of eye. In particular the research will identify aspects of corneal deformation that in turn will help improve the accuracy of refractive surgeries and aid in the management of glaucoma. Also, the knowledge generated through this project will be of value to engineers designing advanced clinical instrument for measuring eye parameters. Read moreRead less
Using 'biological motion' to enhance the nighttime safety of road workers, cyclists, and pedestrians. Pedestrian and cyclist fatalities are a major road safety problem, accounting for a third of road fatalities at an estimated cost of $2.5 billion/year. Late recognition of pedestrians and cyclist by drivers is the main reason for these collisions. We have shown that innovative visibility designs which involve strategic placement of reflective markers on the moveable joints can greatly enhance vi ....Using 'biological motion' to enhance the nighttime safety of road workers, cyclists, and pedestrians. Pedestrian and cyclist fatalities are a major road safety problem, accounting for a third of road fatalities at an estimated cost of $2.5 billion/year. Late recognition of pedestrians and cyclist by drivers is the main reason for these collisions. We have shown that innovative visibility designs which involve strategic placement of reflective markers on the moveable joints can greatly enhance visibility and hence safety of these vulnerable road users. We will extend this research to incorporate evaluation of these visibility solutions in real-world environments and encourage the widespread use of these designs in the real-world through education and policy change.Read moreRead less
Sensory impairments and driving: can older drivers cope with distracters? This research adopts a multi-disciplinary approach to investigate the problems of older drivers, and drivers in general. The research will provide a clear understanding of how visual and auditory distracters impact upon the driving behaviour and safety of individuals with vision and hearing impairment and those experiencing age-related declines in cognitive skills. The research is highly significant in terms of improving o ....Sensory impairments and driving: can older drivers cope with distracters? This research adopts a multi-disciplinary approach to investigate the problems of older drivers, and drivers in general. The research will provide a clear understanding of how visual and auditory distracters impact upon the driving behaviour and safety of individuals with vision and hearing impairment and those experiencing age-related declines in cognitive skills. The research is highly significant in terms of improving our understanding of how sensory impairment and age-related changes impact upon driving performance, the impact of an increasingly complex driving and in-vehicle environment and will provide tangible benefits for the road safety of the wider community.Read moreRead less
The future of corneal refractive reshaping: can we control myopia or is the risk of corneal compromise too great? Refinement of corneal reshaping lens designs, optimised for visual outcomes through manipulation of aberrations, will significantly benefit local contact lens manufacturing and export by expanding the existing market base. This research will also strategically position Australian lens manufacturing to capitalise on the market for myopia-control contact lenses, particularly in the As ....The future of corneal refractive reshaping: can we control myopia or is the risk of corneal compromise too great? Refinement of corneal reshaping lens designs, optimised for visual outcomes through manipulation of aberrations, will significantly benefit local contact lens manufacturing and export by expanding the existing market base. This research will also strategically position Australian lens manufacturing to capitalise on the market for myopia-control contact lenses, particularly in the Asian region. Significant intellectual property will be generated for Australia in terms of enhanced understanding of the role of manipulation of corneal shape in modulating progressive myopia. Outcomes from this project will enhance the international reputation of the UNSW research group, keeping Australian science at the forefront of this area of research.Read moreRead less