Discovery Early Career Researcher Award - Grant ID: DE210101549
Funder
Australian Research Council
Funding Amount
$395,775.00
Summary
A virtual platform for animal–human inhalation toxicity extrapolation. This project aims to remove the long-lasting barrier in extrapolating data from animals to humans by developing an integrated virtual platform. This project expects to fully resolve inhalation exposure differences in nasal airways between commonly used animal surrogates and humans, which could lay scientific underpinnings in developing rigorous interspecies data conversion schemes. Expected outcomes include a versatile inhala ....A virtual platform for animal–human inhalation toxicity extrapolation. This project aims to remove the long-lasting barrier in extrapolating data from animals to humans by developing an integrated virtual platform. This project expects to fully resolve inhalation exposure differences in nasal airways between commonly used animal surrogates and humans, which could lay scientific underpinnings in developing rigorous interspecies data conversion schemes. Expected outcomes include a versatile inhalation exposure risk assessment tool that can be implemented for any airway compartment, enhanced reliability of animal tests, reduced number of animals for testing. This should provide significant benefits in improving occupational health and safety and promoting National/International regulatory changes. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101138
Funder
Australian Research Council
Funding Amount
$368,446.00
Summary
A multi-scale risk assessment platform for inhaled carbon nanotubes. This project aims to develop a coherent risk assessment platform to evaluate human respiratory exposure to carbon nanotubes. Compared to the exponential growth of carbon nanotubes technology, capability of inhalation risk assessment is lagging. The project expects to generate new knowledge on the unique role and risk of carbon nanotube geometry. It will develop a new transport model and create a unified risk assessment. The exp ....A multi-scale risk assessment platform for inhaled carbon nanotubes. This project aims to develop a coherent risk assessment platform to evaluate human respiratory exposure to carbon nanotubes. Compared to the exponential growth of carbon nanotubes technology, capability of inhalation risk assessment is lagging. The project expects to generate new knowledge on the unique role and risk of carbon nanotube geometry. It will develop a new transport model and create a unified risk assessment. The expected outcome is the enhanced risk assessment capability of human exposure to carbon nanotubes, which will provide a significant benefit to the nanotechnology industry through ensuring safety in developing an emergent technology.Read moreRead less
Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilit ....Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilities, and released for community use. These developments underpin future ocean state forecasts, sea ice forecasts, wave forecasts, decadal climate prediction and climate process studies. The project will benefit search and rescue, Defence and shipping operations, and will enhance future climate projections.Read moreRead less
Personalised public transport. This project aims to address urban congestion by utilising people’s travel plans to coordinate journeys. The project expects to generate new knowledge in scalable optimisation, based on innovative modelling of urban transport, and tested on historical data from Melbourne. The expected outcomes of the project are an active transport database and optimised mode choice and routing system, with predicted reductions in congestion based on simulation of its use. This pro ....Personalised public transport. This project aims to address urban congestion by utilising people’s travel plans to coordinate journeys. The project expects to generate new knowledge in scalable optimisation, based on innovative modelling of urban transport, and tested on historical data from Melbourne. The expected outcomes of the project are an active transport database and optimised mode choice and routing system, with predicted reductions in congestion based on simulation of its use. This project aims to design an urban trip advisory system that could be followed by automated vehicles as well as human drivers, to reduce the financial and environmental cost of current urban congestion.Read moreRead less