Neuroimaging changes underpinning improvements in cognition in the elderly. Natural supplements are often used to improve brain and cognitive function, however, we do not know how these supplements work in the brain. Using novel brain imaging scans, the project will investigate whether 12-month administration of two promising natural supplements improves brain markers of ageing and cognitive decline in an elderly population.
Positron Nano-Dosimetry: Fundamental Measurements of Positron Interactions and their use in State-of-the-Art Modelling of Positron Transport. This proposal will provide unique experimental and theoretical information on how positrons, the electron antiparticles, interact with matter, in particular with biologically important molecules. This data will be used in a unique set of modelling approaches which will provide, for the first time, an insight into how positrons are transported through gases ....Positron Nano-Dosimetry: Fundamental Measurements of Positron Interactions and their use in State-of-the-Art Modelling of Positron Transport. This proposal will provide unique experimental and theoretical information on how positrons, the electron antiparticles, interact with matter, in particular with biologically important molecules. This data will be used in a unique set of modelling approaches which will provide, for the first time, an insight into how positrons are transported through gases, liquids and ultimately, soft matter. It will thus have important ramifications for diagnostic tools such as Positron Emission Tomography. The fundamental research will also shed light on one of the key 'mysteries' of life - why the biological building blocks of life possess a definite " handedness", or chirality.Read moreRead less
Preclinical Evaluation Of F-18 Fluoroethyltriazolyl PEGstilbenes As Potential PET Imaging Agents For Alzheimers Disease
Funder
National Health and Medical Research Council
Funding Amount
$673,238.00
Summary
Alzheimer's disease (AD) is the most common form of dementia and is becoming am ever increasing burden to the health system due to the aging of our population. Amyloid plaques are considered the hallmark of AD and a technique for their detection in vivo would be a breakthrough, not only for the diagnosis of AD but also for the development of drugs against AD. Nuclear medicine can image tissue function non-invasively. This project aims to develop new imaging agents to improve diagnosis of AD.