Grid Computing for Phylogenetic Analysis. This interdisciplinary project relates to information technology and bioinformatics, which both can be classified as Frontier Technology in the priority areas outlined by the ARC. Grid computing and using the state-of-art IT technologies to solve grand challenging problems in phylogenetic analysis are forefront research topics in information technology and bioinformatics. The analytical results and new technologies obtained in this project will certainly ....Grid Computing for Phylogenetic Analysis. This interdisciplinary project relates to information technology and bioinformatics, which both can be classified as Frontier Technology in the priority areas outlined by the ARC. Grid computing and using the state-of-art IT technologies to solve grand challenging problems in phylogenetic analysis are forefront research topics in information technology and bioinformatics. The analytical results and new technologies obtained in this project will certainly have significant implications in the relevant areas. New platforms and software developed could have commercial value. It is of great significance that Australia maintains its pioneering position and international reputation in research in Grid computing and its applications.Read moreRead less
Improving the accuracy of phylogenetic reconstruction by improving models of sequence divergence. Phylogenies describe the relationships among species and provide the essential framework for understanding evolutionary processes. They are an essential tool in the identification of functionally important regions in DNA sequences. An important aspect of identifying phylogenies is measuring how DNA sequences change in time. The proposed research will develop sophisticated, practical models of sequen ....Improving the accuracy of phylogenetic reconstruction by improving models of sequence divergence. Phylogenies describe the relationships among species and provide the essential framework for understanding evolutionary processes. They are an essential tool in the identification of functionally important regions in DNA sequences. An important aspect of identifying phylogenies is measuring how DNA sequences change in time. The proposed research will develop sophisticated, practical models of sequence divergence and make them freely available in open source software. The software and models will positively impact on studies seeking to understand Australian biological diversity. The proposed resolution of the eutherian mammal orders will further significantly impact on utilisation of rodents as a model organism for human biology.Read moreRead less