A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interac ....A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interactions, which will greatly complement existing meta-omics approaches. The deliverables include a proof-of-concept system validated for gut-liver axis as well as the creation of new knowledge and framework to assimilate design thinking and advanced manufacturing to elevate tissue engineering into physiology engineering. Read moreRead less
Formation and manipulation of ferroelectric domains with ultrafast light. This project aims to study the fundamental processes governing interaction of ultrafast light pulses with an important class of ferroelectric materials. In particular, it will investigate the physics of light-induced ferroelectric domain reversal in various types of ferroelectrics. Project outcomes will lead to the development of a novel, ultrafast laser domain patterning technique for application in nonlinear photonics, o ....Formation and manipulation of ferroelectric domains with ultrafast light. This project aims to study the fundamental processes governing interaction of ultrafast light pulses with an important class of ferroelectric materials. In particular, it will investigate the physics of light-induced ferroelectric domain reversal in various types of ferroelectrics. Project outcomes will lead to the development of a novel, ultrafast laser domain patterning technique for application in nonlinear photonics, optical memories, and photovoltaics. This technique will be employed to create the first example of three-dimensional domain patterns for versatile wave interactions. This project expects to expand Australia's knowledge in ultrafast laser engineering of materials and contribute towards its rapid uptake by industries, with great potential for commercialisation.Read moreRead less
Microfluidics with core-shell beads: handling liquids like solids. Reducing waste of consumables in chemical reactions promises to solve environmental problems as well as enable novel applications in space. This project aims to establish a revolutionary fluid handling technology that lowers waste in the labs and in satellites. The project deciphers the fundamental physics behind our recent discovery of encapsulating a tiny liquid content in a solid shell, allowing for handling liquid samples lik ....Microfluidics with core-shell beads: handling liquids like solids. Reducing waste of consumables in chemical reactions promises to solve environmental problems as well as enable novel applications in space. This project aims to establish a revolutionary fluid handling technology that lowers waste in the labs and in satellites. The project deciphers the fundamental physics behind our recent discovery of encapsulating a tiny liquid content in a solid shell, allowing for handling liquid samples like solid particles. Examples of the benefit of this project are more precise detection of bacteria on earth and compact reactors in space. The research outcomes are instrumental for promoting a clean environment, good health, and creating new business opportunities, particularly in space industry, for Australians.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100215
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Facility for characterisation of engineered microelectromechanical systems. This facility will provide Australian microelectromechanical (MEMS) researchers with a vital, world-class, capacity for characterisation of micro-machined devices and transducers, enabling them to compete internationally in this emerging field.