Development of electrophoretic cell sorters. The aim of this research is to develop the next generation of cell sorters to scale production of viable sperm and other cell types. Our approach is to understand the factors that control the migration of cells in an electric field so that we can design large-scale devices to purify cells using electrophoretic separation. The outcomes of this research enable large-scale production of viable sperm for human and animal-assisted conception, benefiting in ....Development of electrophoretic cell sorters. The aim of this research is to develop the next generation of cell sorters to scale production of viable sperm and other cell types. Our approach is to understand the factors that control the migration of cells in an electric field so that we can design large-scale devices to purify cells using electrophoretic separation. The outcomes of this research enable large-scale production of viable sperm for human and animal-assisted conception, benefiting infertile couples and the livestock breeding industry. Successful development of an efficient cell separation technology would add significant commercial value to the Australian biomanufacturing sector. Read moreRead less
Scaling microfluidics for cell manufacture. Scaling microfluidics for cell manufacture. This project aims to scale microfluidic devices for cell manufacture. Large-scale cell manufacturing processes (cell selection, gene transfer and culture expansion) are expensive, multistep and labour-intensive processes. Lab-on-a-chip devices can automate and integrate these complex processes at microscale. This project will evaluate a prototype bioreactor. This research is expected to make cell therapies ch ....Scaling microfluidics for cell manufacture. Scaling microfluidics for cell manufacture. This project aims to scale microfluidic devices for cell manufacture. Large-scale cell manufacturing processes (cell selection, gene transfer and culture expansion) are expensive, multistep and labour-intensive processes. Lab-on-a-chip devices can automate and integrate these complex processes at microscale. This project will evaluate a prototype bioreactor. This research is expected to make cell therapies cheap enough to become standard treatment, which would benefit patients with diseases that are incurable by conventional therapies (surgery and drug treatments). It should also benefit the Australian advanced manufacturing sector, particularly biopharmaceutical and cell therapy industries.Read moreRead less