Evolution and mechanisms of interactions in biofilm communities. This project aims to study the long-term experimental evolution of a mixed species bacterial biofilm community. This project expects to gain understanding of the genetic and physiological basis of community evolution. Expected outcomes of this project will be an understanding of how synthetic communities evolve. This will significantly benefit the use of synthetic communities relevant to fields such as antibiotic design, biotechnol ....Evolution and mechanisms of interactions in biofilm communities. This project aims to study the long-term experimental evolution of a mixed species bacterial biofilm community. This project expects to gain understanding of the genetic and physiological basis of community evolution. Expected outcomes of this project will be an understanding of how synthetic communities evolve. This will significantly benefit the use of synthetic communities relevant to fields such as antibiotic design, biotechnology, bioremediation, and synthetic biology where evolution can be inhibited or exploited, respectively.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100842
Funder
Australian Research Council
Funding Amount
$455,057.00
Summary
Roles of emerging pollutants in spreading antimicrobial resistance. Antimicrobial resistance is a growing global challenge, yet the impact of environmental agents on the spread of antimicrobial resistance is poorly understood. Drawing on my recent findings and a tight integration of a model microbial ecology system, this project aims to investigate the impact of environmental pollutants on the colonisation and spread of antimicrobial resistance in situ ecological communities. This project expect ....Roles of emerging pollutants in spreading antimicrobial resistance. Antimicrobial resistance is a growing global challenge, yet the impact of environmental agents on the spread of antimicrobial resistance is poorly understood. Drawing on my recent findings and a tight integration of a model microbial ecology system, this project aims to investigate the impact of environmental pollutants on the colonisation and spread of antimicrobial resistance in situ ecological communities. This project expects to generate new knowledge at the forefront of research into antimicrobial resistance in a complex ecosystem. The outcomes should provide a deep mechanistic understanding of environmental factors associated with antimicrobial resistance, with applications to antimicrobial resistance risk management for One Health.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100373
Funder
Australian Research Council
Funding Amount
$447,320.00
Summary
The role of resource fluctuations in structuring microbial communities. The flow of nutrients through ecological systems fluctuates through time and yet the impact this variability has on the maintenance of biodiversity is poorly understood. Drawing on emerging theory and a tight integration of modelling and experiments in a model microbial system, this project aims to investigate the impact of modified nutrient regimes on the structure and stability of ecological communities. This project expec ....The role of resource fluctuations in structuring microbial communities. The flow of nutrients through ecological systems fluctuates through time and yet the impact this variability has on the maintenance of biodiversity is poorly understood. Drawing on emerging theory and a tight integration of modelling and experiments in a model microbial system, this project aims to investigate the impact of modified nutrient regimes on the structure and stability of ecological communities. This project expects to generate new knowledge at the forefront of research into diversity maintenance, ecosystem functioning and higher-order interactions. The outcomes should provide a deep mechanistic understanding of microbial community dynamics, with applications from animal health to environmental flows and insect pest management.Read moreRead less
Can cyanobacteria use organic nutrients to thrive in future oceans? Marine cyanobacteria are central to regulating the global climate and underpin entire marine food webs. Though they possess genes necessary to uptake diverse organic nutrients, we know very little about whether and how organic nutrients shape the physiology and ecology of cyanobacteria. Using our innovative high-throughput approach, this project aims to systematically characterise organic nutrient uptake in picocyanobacteria. O ....Can cyanobacteria use organic nutrients to thrive in future oceans? Marine cyanobacteria are central to regulating the global climate and underpin entire marine food webs. Though they possess genes necessary to uptake diverse organic nutrients, we know very little about whether and how organic nutrients shape the physiology and ecology of cyanobacteria. Using our innovative high-throughput approach, this project aims to systematically characterise organic nutrient uptake in picocyanobacteria. Our molecules-to-ecosystems approach expects to transform our understanding of alternate nutrient acquisition in cyanobacteria and how it may shape populations of these important photosynthetic organisms in a rapidly-changing ocean landscape. Read moreRead less
Predatory protists: natural weapons for soil-borne pathogen control. This project aims to understand the mechanistic interactions of predatory protists and fungal pathogens and develop innovative biotechnologies using the protists to suppress soil-borne pathogens. By directly preying on fungal pathogens or activating plant-beneficial bacteria to combat them, the soil predatory protists will be identified, cultivated and utilised to improve disease management. Expected outcomes of this project wi ....Predatory protists: natural weapons for soil-borne pathogen control. This project aims to understand the mechanistic interactions of predatory protists and fungal pathogens and develop innovative biotechnologies using the protists to suppress soil-borne pathogens. By directly preying on fungal pathogens or activating plant-beneficial bacteria to combat them, the soil predatory protists will be identified, cultivated and utilised to improve disease management. Expected outcomes of this project will include a mechanistic understanding of the contribution of protists to pathogen suppression and an innovative, protist-based disease management tool. The novel technologies developed in this project have potentials to benefit Australian agriculture and land management.Read moreRead less
Unlocking Viral Contribution to Terrestrial Nitrogen Cycling. This project aims to investigate how soil viruses steer key nitrogen cycling microorganisms and processes, by utilising emerging approaches of viromes, DNA-stable-isotope probing, and Raman-spectroscopy-based single-cell-sorting technology. This project expects to generate new knowledge in harnessing the potential of soil viruses to improve fertiliser nitrogen use efficiency through manipulating the biological pathways of nitrogen los ....Unlocking Viral Contribution to Terrestrial Nitrogen Cycling. This project aims to investigate how soil viruses steer key nitrogen cycling microorganisms and processes, by utilising emerging approaches of viromes, DNA-stable-isotope probing, and Raman-spectroscopy-based single-cell-sorting technology. This project expects to generate new knowledge in harnessing the potential of soil viruses to improve fertiliser nitrogen use efficiency through manipulating the biological pathways of nitrogen losses from agricultural ecosystems. Expected outcomes of this project include novel and comprehensive evidence for the roles of soil viruses in controlling terrestrial nitrogen cycling processes. This should provide significant benefits to Australian agriculture and environmental management.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100338
Funder
Australian Research Council
Funding Amount
$457,155.00
Summary
Barking up the right trees – A microbial solution for our methane problem. This project aims to unveil the microbial diversity and metabolic capabilities of bark-dwelling microbial communities in Australian forests. Trees perform an important climatic function in sequestering atmospheric carbon, however the role of tree bark-associated microbiome in regulating other climate-active trace gasses such as methane, hydrogen and carbon monoxide is unknown. Combining cutting-edge molecular and biogeoch ....Barking up the right trees – A microbial solution for our methane problem. This project aims to unveil the microbial diversity and metabolic capabilities of bark-dwelling microbial communities in Australian forests. Trees perform an important climatic function in sequestering atmospheric carbon, however the role of tree bark-associated microbiome in regulating other climate-active trace gasses such as methane, hydrogen and carbon monoxide is unknown. Combining cutting-edge molecular and biogeochemical approaches, this project aims to characterise and quantify trace gas oxidation rates of forest bark microbiome. The anticipated outcomes include fundamental knowledge surrounding bark-associated microbial trace gas oxidation within global biogeochemical cycles, and insights into their response to climatic variables.Read moreRead less
Global integration of microbial community and climate data. Microbial communities in the environment control the cycling of carbon and nutrients on Earth, but climate models do not directly incorporate microbial inputs. This interdisciplinary project will link planetary-scale climate modelling data with novel large-scale microbial community analysis, using climate information to provide insight into the fantastic diversity of microbial processes on our planet. The interdisciplinary approach will ....Global integration of microbial community and climate data. Microbial communities in the environment control the cycling of carbon and nutrients on Earth, but climate models do not directly incorporate microbial inputs. This interdisciplinary project will link planetary-scale climate modelling data with novel large-scale microbial community analysis, using climate information to provide insight into the fantastic diversity of microbial processes on our planet. The interdisciplinary approach will inform the next generation of climate models and better predict our future climate’s feedbacks. Conversely, it will make progress on the grand challenge of understanding microbial community function by enabling microbial ecology to be treated as a data-intensive machine learning problem.Read moreRead less
Can eco-evolutionary theories explain outcomes of microbiome coalescence . Environmental microbial communities are among the most abundant and diverse natural communities, responsible for many ecologically and economically important ecosystem functions, including primary productivity and climate regulation. This project aims to identify the biotic and abiotic factors that regulate community and functional outcomes of microbiome coalescence (the mixing of two different communities) caused by natu ....Can eco-evolutionary theories explain outcomes of microbiome coalescence . Environmental microbial communities are among the most abundant and diverse natural communities, responsible for many ecologically and economically important ecosystem functions, including primary productivity and climate regulation. This project aims to identify the biotic and abiotic factors that regulate community and functional outcomes of microbiome coalescence (the mixing of two different communities) caused by natural and anthropogenic activities. The outcomes will provide a unifying ecological framework to predict variation in microbiomes across different scales, ecosystem types and disturbances, and will generate critical knowledge for the development of effective microbiome products, a rapidly growing industryRead moreRead less
HoliCOW - A holobiont strategy to uncover the core microbiome in cows. Human population growth is driving a rise in cattle production for food, which necessitates sustainable practices that simultaneously optimise animal nutrition while reducing methane emissions, a critical greenhouse gas. This project aims to unravel and exploit biological connections across the cow holobiont, which pertains to the feed cows eat, their bodily function and the microbes in their rumen. This project will leverage ....HoliCOW - A holobiont strategy to uncover the core microbiome in cows. Human population growth is driving a rise in cattle production for food, which necessitates sustainable practices that simultaneously optimise animal nutrition while reducing methane emissions, a critical greenhouse gas. This project aims to unravel and exploit biological connections across the cow holobiont, which pertains to the feed cows eat, their bodily function and the microbes in their rumen. This project will leverage multi-layered molecular data derived from the cow holobiont to identify, characterise and ultimately control the core rumen microbiome that causes methane production in animals. The outcome will be new knowledge to facilitate microbiome-based interventions that benefit animal production and reduce its carbon footprint.Read moreRead less