Revealing the evolutionary and ecological dynamics of avian influenza virus. This project aims to understand how avian influenza virus (AIV) emerges, evolves and spreads in wild birds. AIV has the potential to devastate the poultry industry and cause human pandemics, but the factors that shape the genetic diversity of AIV in its wild bird reservoir are poorly understood. The project plans to combine genomic, ecological and phylogenetic approaches to reveal key aspects of AIV evolution, as well a ....Revealing the evolutionary and ecological dynamics of avian influenza virus. This project aims to understand how avian influenza virus (AIV) emerges, evolves and spreads in wild birds. AIV has the potential to devastate the poultry industry and cause human pandemics, but the factors that shape the genetic diversity of AIV in its wild bird reservoir are poorly understood. The project plans to combine genomic, ecological and phylogenetic approaches to reveal key aspects of AIV evolution, as well as the risk for future viral emergence. Using sampling sites in Australia and Antarctica, it plans to investigate AIV diversity, the evolutionary dynamics of AIV in wild birds and poultry, and the role played by environmental transmission in AIV ecology.Read moreRead less
A novel process for removing phosphorus microbiologically from wastewater. Australia is a water limited continent, and its rivers and lakes are priceless assets, but because of climatic conditions, these are especially sensitive to blooms of 'blue green algae'. Some are highly toxic, and water containing them is unsuitable for most purposes. Current technology for P removal requires constructing complex plant configurations, and most of these operate unpredictably and unreliably. This project ....A novel process for removing phosphorus microbiologically from wastewater. Australia is a water limited continent, and its rivers and lakes are priceless assets, but because of climatic conditions, these are especially sensitive to blooms of 'blue green algae'. Some are highly toxic, and water containing them is unsuitable for most purposes. Current technology for P removal requires constructing complex plant configurations, and most of these operate unpredictably and unreliably. This project will develop and fully evaluate a revolutionarily different alternative with a fully aerobic system, capable of being added onto the end of a conventional treatment plant, making protection of rivers and streams simpler and more feasible. Read moreRead less
Reserving nitrogen in soils through microbial nitrate reduction to ammonium. This project aims to identify those microbes able to transform nitrate to ammonium and thus increase soil nitrogen conservation. More than 50 per cent of the nitrogen in fertilisers applied to soils is lost into the environment, which is both a financial loss to farmers and a main anthropogenic source of nitrogen pollution. Some microbes can transform nitrate into ammonium through dissimilatory reduction (DNRA) and thus ....Reserving nitrogen in soils through microbial nitrate reduction to ammonium. This project aims to identify those microbes able to transform nitrate to ammonium and thus increase soil nitrogen conservation. More than 50 per cent of the nitrogen in fertilisers applied to soils is lost into the environment, which is both a financial loss to farmers and a main anthropogenic source of nitrogen pollution. Some microbes can transform nitrate into ammonium through dissimilatory reduction (DNRA) and thus increase soil nitrogen retention. However, the DNRA process and the responsible microbial groups remain largely unknown. This project plans to use isotope tracing and biomolecular approaches to identify those DNRA microbial groups and elucidate the DNRA reaction process. The findings may support the use of DNRA to improve soil nitrogen.Read moreRead less
The genomics of adaptation in Wolbachia pipientis, an emerging biocontrol agent. Australians are increasingly exposed to insect-transmitted diseases such as dengue fever. Novel biocontrol methods using the bacterium Wolbachia aim to control insect populations to reduce disease transmission. Our research will be the first to investigate genomic variation and the process of adaptation to new insect hosts in Wolbachia. The novel data and understanding of evolutionary processes we generate will be c ....The genomics of adaptation in Wolbachia pipientis, an emerging biocontrol agent. Australians are increasingly exposed to insect-transmitted diseases such as dengue fever. Novel biocontrol methods using the bacterium Wolbachia aim to control insect populations to reduce disease transmission. Our research will be the first to investigate genomic variation and the process of adaptation to new insect hosts in Wolbachia. The novel data and understanding of evolutionary processes we generate will be critical for screening bacterial biocontrol candidates and designing biocontrol release strategies. It will also strengthen the position of Australian research as a world-leader in the fusion of post-genomics and applied microbiology. Read moreRead less
How antibiotic resistance is transferred from animal manure to vegetable. This project aims to decipher the transmission routes of antibiotic resistance from animal manure to manured soil and vegetable. Antibiotic resistance genes (ARGs) threaten human health, but the pathways and mechanisms for transmission of ARGs in the environment are unknown. This project will investigate all the major classes of ARGs in typical animal manure and vegetable form, and possible routes for their transmission fr ....How antibiotic resistance is transferred from animal manure to vegetable. This project aims to decipher the transmission routes of antibiotic resistance from animal manure to manured soil and vegetable. Antibiotic resistance genes (ARGs) threaten human health, but the pathways and mechanisms for transmission of ARGs in the environment are unknown. This project will investigate all the major classes of ARGs in typical animal manure and vegetable form, and possible routes for their transmission from manure to soil and to vegetable surfaces and endophytic bacterial communities. The results are expected to identify the ARGs indicators likeliest to spread into the food chain, and develop management options to tackle the environmental antibiotic resistance.Read moreRead less
The geomicrobiology and (bio)geochemistry of platinum, palladium and rhodium. Few economic (Platinum) Pt, (Palladium) Pd or (Rhodium) Rh deposits are known in Australia despite an abundance of potential host rock. By improving onshore exploration techniques this project will ensure the supply of these strategic metals to the Australian economy. By integrating geochemical, molecular microbial and microanalyses (e.g., synchrotron) techniques this project will also: (i) enhance Australia's status i ....The geomicrobiology and (bio)geochemistry of platinum, palladium and rhodium. Few economic (Platinum) Pt, (Palladium) Pd or (Rhodium) Rh deposits are known in Australia despite an abundance of potential host rock. By improving onshore exploration techniques this project will ensure the supply of these strategic metals to the Australian economy. By integrating geochemical, molecular microbial and microanalyses (e.g., synchrotron) techniques this project will also: (i) enhance Australia's status in the breakthrough science of Geomicrobiology; (ii) secure a leading role for Australian science in the assessment of anthropogenic Pt, Pd and Rh pollution; (iii) access expertise developed overseas by fostering international collaborations; and (iv) explore the transformational capabilities of microbiota for ore-processing of and nano-particle production.Read moreRead less
Enhanced coral stress tolerance via manipulation of prokaryotic symbionts. The project aims to develop a novel approach to improve environmental stress tolerance in corals. Coral reefs are under threat from a range of stressors that have led to massive declines in coral cover and health worldwide. There is now great concern that the rate of environmental change is outpacing the natural capacity of corals to acclimatise, adapt and survive. Although it is important to address the root causes of cl ....Enhanced coral stress tolerance via manipulation of prokaryotic symbionts. The project aims to develop a novel approach to improve environmental stress tolerance in corals. Coral reefs are under threat from a range of stressors that have led to massive declines in coral cover and health worldwide. There is now great concern that the rate of environmental change is outpacing the natural capacity of corals to acclimatise, adapt and survive. Although it is important to address the root causes of climate change, a focus on strategies to mitigate its impacts is also required. This project explores the potential to augment the capacity of corals to tolerate stress through the manipulation of their associated prokaryotic communities. This project may result in novel coral reef restoration approaches.Read moreRead less
Cultivating numerically significant soil bacteria. The vast majority of soil bacteria have not been able to be studied in the laboratory because they cannot be grown outside the soil. They are therefore termed unculturable. Most of these belong to groups that are completely unstudied. Advances made in the Janssen lab have overcome this impediment to laboratory cultivation of numerically abundant and globally distributed soil bacteria. This project will develop these advances to generate simple a ....Cultivating numerically significant soil bacteria. The vast majority of soil bacteria have not been able to be studied in the laboratory because they cannot be grown outside the soil. They are therefore termed unculturable. Most of these belong to groups that are completely unstudied. Advances made in the Janssen lab have overcome this impediment to laboratory cultivation of numerically abundant and globally distributed soil bacteria. This project will develop these advances to generate simple and widely applicable methods to enable many of the previously unculturable soil bacteria to be studied. This will allow assessments of their ecological roles and biotechnological potentials to be made.Read moreRead less
Anaerobic methane oxidation in the deep sub-seafloor microbial biosphere. Microbes that control the emission of the greenhouse gas methane from the seafloor to the Earth's atmosphere effectively slow global warming. This project aims to understand the microbial controls for this process to improve an understanding of this planet's natural carbon cycle, and yield valuable information for marine CO2 geosequestration strategies.