Investigating the role of Zona Incerta RXFP3+ cells in learning and memory. Learning and memory are fundamental to human and animal behaviour. We identified a specific population of cells in the zona incerta of the brain, where activation inhibits expression of memory, and facilitates the acquisition of new learning. Aside from our observations, nothing is currently known about the anatomy and function of these cells. This project aims to map how they connect to the rest of the brain, to observe ....Investigating the role of Zona Incerta RXFP3+ cells in learning and memory. Learning and memory are fundamental to human and animal behaviour. We identified a specific population of cells in the zona incerta of the brain, where activation inhibits expression of memory, and facilitates the acquisition of new learning. Aside from our observations, nothing is currently known about the anatomy and function of these cells. This project aims to map how they connect to the rest of the brain, to observe how these connections are recruited during learning and memory, and then to test their function experimentally. The outcomes will extend the known neural circuitry that controls learning by defining how and where these unexplored pathways fit within it; thus advancing knowledge regarding neural regulation of behaviour.
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Discovery Early Career Researcher Award - Grant ID: DE170100106
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Measuring interference from prior memories using experience sampling. The project aims to better understand the causes of forgetting in recognition memory. This project will measure participants' experiences using smartphone technology for four weeks before a recognition memory experiment. Similarities between the images in the experiment and images in prior experience can be used to fully specify all interference components within a computational model of recognition memory, leading to a comple ....Measuring interference from prior memories using experience sampling. The project aims to better understand the causes of forgetting in recognition memory. This project will measure participants' experiences using smartphone technology for four weeks before a recognition memory experiment. Similarities between the images in the experiment and images in prior experience can be used to fully specify all interference components within a computational model of recognition memory, leading to a complete model of recognition memory. Better understanding the causes of forgetting in recognition memory could show how interference contributes to memory impairments in ageing, and ultimately Alzheimer’s and other clinical disorders.Read moreRead less