Investigating the role of Zona Incerta RXFP3+ cells in learning and memory. Learning and memory are fundamental to human and animal behaviour. We identified a specific population of cells in the zona incerta of the brain, where activation inhibits expression of memory, and facilitates the acquisition of new learning. Aside from our observations, nothing is currently known about the anatomy and function of these cells. This project aims to map how they connect to the rest of the brain, to observe ....Investigating the role of Zona Incerta RXFP3+ cells in learning and memory. Learning and memory are fundamental to human and animal behaviour. We identified a specific population of cells in the zona incerta of the brain, where activation inhibits expression of memory, and facilitates the acquisition of new learning. Aside from our observations, nothing is currently known about the anatomy and function of these cells. This project aims to map how they connect to the rest of the brain, to observe how these connections are recruited during learning and memory, and then to test their function experimentally. The outcomes will extend the known neural circuitry that controls learning by defining how and where these unexplored pathways fit within it; thus advancing knowledge regarding neural regulation of behaviour.
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Algorithms for Memory Management and Memory Design in Embedded Systems. Given the importance of embedded systems technology, Australia must secure a place among significant innovators in the field of embedded systems design. Our research aims at novel algorithmic solutions for customization and resource management for embedded processors. Thus, besides generating intellectual property, our research can be fully commercialized in Australia, because it does not require complex and expensive techn ....Algorithms for Memory Management and Memory Design in Embedded Systems. Given the importance of embedded systems technology, Australia must secure a place among significant innovators in the field of embedded systems design. Our research aims at novel algorithmic solutions for customization and resource management for embedded processors. Thus, besides generating intellectual property, our research can be fully commercialized in Australia, because it does not require complex and expensive technologies and other resources available only to the world's largest corporations. In addition, during our research a number of undergraduate and graduate students will get a chance to get training in the cutting edge embedded systems design, optimization and testing.Read moreRead less
Super-resolution in microscopy and optical recording. The classical resolution limit imposes severe restrictions on the performance of optical instruments, especially in optical microscopy and optical recording. Improved understanding of the fundamental principles involved in super-resolution should allow substantial increases in resolution to be achieved. We aim to explore theoretically and experimentally the performance of different super-resolution schemes alone and in combination, including ....Super-resolution in microscopy and optical recording. The classical resolution limit imposes severe restrictions on the performance of optical instruments, especially in optical microscopy and optical recording. Improved understanding of the fundamental principles involved in super-resolution should allow substantial increases in resolution to be achieved. We aim to explore theoretically and experimentally the performance of different super-resolution schemes alone and in combination, including optical masks, near-field optics, detector arrays, multi-photon imaging and digital deconvolution. Selected methods will be demonstrated with practical examples in multi-photon microscopy. Applications in super-high density optical recording will also be studied.Read moreRead less
Towards a high density silicon phase change memory device. This project builds upon our exciting recent findings that amorphous silicon can be transformed to a conducting crystalline phase following small-scale indentation. Furthermore the process is reversible as re-indentation can induce a transformation back to insulating amorphous silicon. This process appears to occur in extremely small (nanoscale) volumes of silicon. We plan to explore the viability of exploiting this behaviour to develo ....Towards a high density silicon phase change memory device. This project builds upon our exciting recent findings that amorphous silicon can be transformed to a conducting crystalline phase following small-scale indentation. Furthermore the process is reversible as re-indentation can induce a transformation back to insulating amorphous silicon. This process appears to occur in extremely small (nanoscale) volumes of silicon. We plan to explore the viability of exploiting this behaviour to develop an entirely new information storage system: a high-density silicon phase change memory. This project aims to study small-scale transformation behaviour in silicon and to design demonstrator memory devices based on both micro-electromechanical systems and solid state technologies.Read moreRead less