Real-time neuronal network imaging using diamond optrode arrays. The project aims to develop new imaging technology for real time recording of electrical activity from cell and neuronal networks with unprecedented resolution and scale. The technology innovation stems from an optical defect in diamond which can be engineered to sensitively detect local changes in electric field. The all-optical diamond optrode array devices will be applied to biological model systems including cardiomyocytes, mam ....Real-time neuronal network imaging using diamond optrode arrays. The project aims to develop new imaging technology for real time recording of electrical activity from cell and neuronal networks with unprecedented resolution and scale. The technology innovation stems from an optical defect in diamond which can be engineered to sensitively detect local changes in electric field. The all-optical diamond optrode array devices will be applied to biological model systems including cardiomyocytes, mammalian cells, and neurons; and will be benchmarked against current state-of-the-art technologies. The knowledge gained from the high density recordings will aid predictive models of disease and will lead to an improved understanding of the brain’s micro circuity and functional connectome.Read moreRead less
Metal dielectric microstructures: Tuneable metamaterials to medical devices. This project aims to demonstrate tuneable metamaterials fabricated economically and in volume. Tuneability is sought after and difficult to realise. This project will switch a metamaterial from metallic to dielectric behaviour, and dynamically vary the magnification of a hyperlens. To do this, it will create a micro/nanofabrication technology platform with potential widespread uses in high technology manufacturing. It e ....Metal dielectric microstructures: Tuneable metamaterials to medical devices. This project aims to demonstrate tuneable metamaterials fabricated economically and in volume. Tuneability is sought after and difficult to realise. This project will switch a metamaterial from metallic to dielectric behaviour, and dynamically vary the magnification of a hyperlens. To do this, it will create a micro/nanofabrication technology platform with potential widespread uses in high technology manufacturing. It expects to improve multi-modal neural interfaces for optogenetic research and implantable biomedical devices such as cochlear implants.Read moreRead less