Sequence-Defined Polymers with Optical Information Readout. The project aim is to introduce the first optically readable sequence-defined polymers based on fluorophore excimers, whose information content can be read as simply as conventional barcodes. These macromolecular barcodes, embedded in solid polymer matrices, will overcome the current limitations of reading information from synthetic macromolecules. An interdisciplinary effort will fuse chemistry, law, and criminology to develop the tec ....Sequence-Defined Polymers with Optical Information Readout. The project aim is to introduce the first optically readable sequence-defined polymers based on fluorophore excimers, whose information content can be read as simply as conventional barcodes. These macromolecular barcodes, embedded in solid polymer matrices, will overcome the current limitations of reading information from synthetic macromolecules. An interdisciplinary effort will fuse chemistry, law, and criminology to develop the technology in ways that are expected to address illicit plastic waste trafficking – ending the anonymity of polymer waste by creating a regulatory and criminological paradigm for tracing plastic waste to hold actors in the value chain responsible.Read moreRead less
Microspheres from (Sun)Light – A Sustainable Materials Platform. This project will break new ground in light-induced step-growth precipitation polymerisation techniques for polymer particle formation that do not require any initiator, surfactants, additives or heating, thus constituting an environmentally friendly process. The project will establish the underpinning photochemical particle formation processes and establish a broad monomer base for the production of particles with a wide property ....Microspheres from (Sun)Light – A Sustainable Materials Platform. This project will break new ground in light-induced step-growth precipitation polymerisation techniques for polymer particle formation that do not require any initiator, surfactants, additives or heating, thus constituting an environmentally friendly process. The project will establish the underpinning photochemical particle formation processes and establish a broad monomer base for the production of particles with a wide property profile, including particles with tailored surface properties and the ability to degrade upon a defined trigger signal. Scaling the particles' synthesis, including using Australian sunlight, will enable multi-gram production allowing real-world applications.Read moreRead less
Sustainable Reversible Polymerisation. This project aims to address the problem of the current lack of efficient chemical recyclability of polymers. For the majority of polymers, no methods exist so far that are scalable and economic at the same time. To reach this aim, we will utilise a mixture of clever chemical concepts with continuous flow engineering. This project expects to generate new knowledge in the area of depolymerisation and chemical recycling methods. The expected outcome of this p ....Sustainable Reversible Polymerisation. This project aims to address the problem of the current lack of efficient chemical recyclability of polymers. For the majority of polymers, no methods exist so far that are scalable and economic at the same time. To reach this aim, we will utilise a mixture of clever chemical concepts with continuous flow engineering. This project expects to generate new knowledge in the area of depolymerisation and chemical recycling methods. The expected outcome of this project is a scalable process and its practical demonstration for full chemical recycling of various polymers used in everyday applications. This will provide a benefit to society as it allows to tackle plastic pollution problems, and creates avenues to green methods in plastic recycling.
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Self-assembled supramolecular cages for guest binding and catalysis. This project aims to construct a family of supramolecular metal-containing cage-shaped molecules that possess specialised binding pockets with unique chemical properties that mimic enzymes. Many existing cage molecules contain well-defined three dimensional cavities reminiscent of enzymes' active sites. However, unlike natural systems they do not contain "active" metals with free coordination sites, and this limits their cataly ....Self-assembled supramolecular cages for guest binding and catalysis. This project aims to construct a family of supramolecular metal-containing cage-shaped molecules that possess specialised binding pockets with unique chemical properties that mimic enzymes. Many existing cage molecules contain well-defined three dimensional cavities reminiscent of enzymes' active sites. However, unlike natural systems they do not contain "active" metals with free coordination sites, and this limits their catalytic ability. This project aims to prepare a large family of robust organic cages quickly and easily, and subsequently incorporate metals containing free active sites that point into the cage cavity. It is expected that this will deliver strong and selective guest binding, and efficient and selective catalysis.Read moreRead less
An in-built depolymerisation solution for polyethylene waste. This project aims to design enzymes that can be embedded into polyethylene, and later activated by the elevated temperatures of a compost heap, to depolymerise the plastic to small molecules. There are no good options available for the controlled decomposition of polyethylene waste at present, and instead researchers have focussed on solutions that rely on modifications to the underlying chemistry of the backbone and or collection to ....An in-built depolymerisation solution for polyethylene waste. This project aims to design enzymes that can be embedded into polyethylene, and later activated by the elevated temperatures of a compost heap, to depolymerise the plastic to small molecules. There are no good options available for the controlled decomposition of polyethylene waste at present, and instead researchers have focussed on solutions that rely on modifications to the underlying chemistry of the backbone and or collection to a central facility. Our approach would result in an in-built decomposition that does not require collection and recycling in a central facility. Since it is based on a depolymerisation mechanism it does not result in the production of harmful, partially disintegrated microplastics.Read moreRead less
A platform technology for developing mesoporous polymer particles. This project aims to apply polymerisation-induced self-assembly process to develop triggerable mesoporous polymer particles as advanced functional materials for various applications. By combining this scalable process and automated synthesis technique, mesoporous polymer particles that can disassemble in response to external triggers, such as light, redox conditions and enzymes, will be developed. The knowledge gained from this r ....A platform technology for developing mesoporous polymer particles. This project aims to apply polymerisation-induced self-assembly process to develop triggerable mesoporous polymer particles as advanced functional materials for various applications. By combining this scalable process and automated synthesis technique, mesoporous polymer particles that can disassemble in response to external triggers, such as light, redox conditions and enzymes, will be developed. The knowledge gained from this research will allow researchers to fully understand the formation and evolution mechanism of inverse bicontinuous structures observed in nature and produced in synthetic labs. Importantly, the applications of these novel stimuli-responsive particles as nano-carriers and templating scaffolds will be investigated.Read moreRead less
Unravelling Efficient Nucleic Acid Delivery Using Multilayer Nanoparticles. Developing smarter nanoparticles is critical for maximising the potential of biological therapeutics such as nucleic acids. Currently, the efficiency of nanoparticle delivery remains low due to the inability of carriers to migrate different biological regions. The aim of this project is to develop responsive polymer nanoparticles that can more effectively migrate cell barriers by a two-staged release based on the combina ....Unravelling Efficient Nucleic Acid Delivery Using Multilayer Nanoparticles. Developing smarter nanoparticles is critical for maximising the potential of biological therapeutics such as nucleic acids. Currently, the efficiency of nanoparticle delivery remains low due to the inability of carriers to migrate different biological regions. The aim of this project is to develop responsive polymer nanoparticles that can more effectively migrate cell barriers by a two-staged release based on the combination of different self-immolative polymers. This project will allow the development of design rules for understanding how nanoparticle structure can be optimised to improve nucleic acid delivery. This work will have important benefits such as developing new nanotechnology industry and skilled graduates for Australia.
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Synthesising novel phases of carbon by shear-induced phase transformations. Carbon forms the hardest known solids and offers the opportunity for new materials with outstanding properties. The aim of this project is to establish a new technology for synthesising dense, diamond-like carbon materials without the need for high temperatures. The approach uses shear stress caused by non-hydrostatic compressions to drive phase changes in solids. Guided by modelling and using novel experimental techniqu ....Synthesising novel phases of carbon by shear-induced phase transformations. Carbon forms the hardest known solids and offers the opportunity for new materials with outstanding properties. The aim of this project is to establish a new technology for synthesising dense, diamond-like carbon materials without the need for high temperatures. The approach uses shear stress caused by non-hydrostatic compressions to drive phase changes in solids. Guided by modelling and using novel experimental techniques, this project seeks to understand and then exploit this remarkable phase change phenomenon. Expected outcomes include hard and tough coatings for high performance tools, impermeable encapsulations to enhance the longevity of bionic implants and a possible explanation for the mystery of deep earthquakes.Read moreRead less
Novel Hybrid Nanotechnologies by Infiltration of Functional Polymers. Hybrid inorganic-organic materials have important applications in energy, environmental and health technologies. Sequential infiltration synthesis (SIS) of polymers is a recently introduced approach to preparing such hybrid structures. Advancement in the field is however hampered by lack of fundamental understanding of the mechanisms of interactions of SIS molecules with polymers, and the narrow range of polymers studied so fa ....Novel Hybrid Nanotechnologies by Infiltration of Functional Polymers. Hybrid inorganic-organic materials have important applications in energy, environmental and health technologies. Sequential infiltration synthesis (SIS) of polymers is a recently introduced approach to preparing such hybrid structures. Advancement in the field is however hampered by lack of fundamental understanding of the mechanisms of interactions of SIS molecules with polymers, and the narrow range of polymers studied so far. This project aims to build a fundamental framework for the development of SIS through systematic studies of interactions of polymers and SIS molecules. Expected outcomes include new methods for constructing nanostructures using functional polymers and novel fabrication processes exploiting polymer self-assembly.Read moreRead less
Design of novel polymer electrolytes for solid state sodium batteries. Solid-state sodium-ion batteries can provide a cheaper, safer, and greener alternative solution to store energy. This project aims to investigate the design of advanced polymer electrolyte materials to address the challenge for the development of all solid-state sodium batteries. New understandings in polymer chemistry, interfacial properties and cell performance will be gained through co-active approaches combining molecular ....Design of novel polymer electrolytes for solid state sodium batteries. Solid-state sodium-ion batteries can provide a cheaper, safer, and greener alternative solution to store energy. This project aims to investigate the design of advanced polymer electrolyte materials to address the challenge for the development of all solid-state sodium batteries. New understandings in polymer chemistry, interfacial properties and cell performance will be gained through co-active approaches combining molecular simulations, experimental characterizations, and battery prototyping. This project will provide significant benefits in developing new functional materials, new knowledge, and advanced battery techniques, benefiting Australia’s clean energy storage sector.Read moreRead less