Atomic scale precision engineering of cell-material interfaces. This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and cell membranes through x-ray diffraction and molecular simulation. The project will generate knowledge to enable atomic scale engineering of peptide nanomaterials, and exploitation of these materials to modulate cell responses. Expected outcomes include designed peptide nanostructures with specific chemical and physical ....Atomic scale precision engineering of cell-material interfaces. This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and cell membranes through x-ray diffraction and molecular simulation. The project will generate knowledge to enable atomic scale engineering of peptide nanomaterials, and exploitation of these materials to modulate cell responses. Expected outcomes include designed peptide nanostructures with specific chemical and physical cues to promote sustainable growth of desired cells, whilst inhibiting undesirable responses. These outcomes should provide benefits in terms of a practical toolkit for tailoring structure and function of peptide nanostructures and open up a new era in molecular design of smart biomaterials. This easily scalable, new materials platform will contribute to emerging high-value manufacturing industries in Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100148
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
An X-ray scattering facility for bulk and interfacial nanostructure. This project aims to establish an integrated, three-beamline facility for small- and wide-angle x-ray scattering (SWAXS) investigations of nanostructured materials in the bulk phase and at surfaces, focussed on soft and self-assembled materials such as polymers, biomaterials and molecular gels. This facility will act as a node for researchers in and around Sydney, providing research tools and training in small-angle scattering. ....An X-ray scattering facility for bulk and interfacial nanostructure. This project aims to establish an integrated, three-beamline facility for small- and wide-angle x-ray scattering (SWAXS) investigations of nanostructured materials in the bulk phase and at surfaces, focussed on soft and self-assembled materials such as polymers, biomaterials and molecular gels. This facility will act as a node for researchers in and around Sydney, providing research tools and training in small-angle scattering. It will provide cutting-edge research tools and advanced training in small-angle scattering. It is expected to yield important science in its own right, and enable researchers to more effectively use beamlines at Australian and international major research facilities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100096
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
A unique soft matter high-performance scanning probe microscopy (HP-SPM) facility. Soft matter research touches every aspect of our lives as it covers materials from the range of plastics found in cars, television sets and other mass-manufactured products, to new medical materials for tissue engineering and sensors. The proposed facility will enable Australia's leading scientists in this area to understand better how soft matter, including both biological and new advanced soft materials, behave ....A unique soft matter high-performance scanning probe microscopy (HP-SPM) facility. Soft matter research touches every aspect of our lives as it covers materials from the range of plastics found in cars, television sets and other mass-manufactured products, to new medical materials for tissue engineering and sensors. The proposed facility will enable Australia's leading scientists in this area to understand better how soft matter, including both biological and new advanced soft materials, behaves on the nano-scale level. This will put Australian researchers and engineers in a leading position for developing new treatments against cancer and other diseases, as well as harnessing the power of biology for application in areas such as waste treatment and energy production.Read moreRead less
Atomic scale precision engineering of cell-material interfaces. This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and cell membranes through x-ray diffraction and molecular simulation. The project will generate knowledge to enable atomic scale engineering of peptide nanomaterials, and exploitation of these materials to modulate cell responses. Expected outcomes include designed peptide nanostructures with specific chemical and physical ....Atomic scale precision engineering of cell-material interfaces. This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and cell membranes through x-ray diffraction and molecular simulation. The project will generate knowledge to enable atomic scale engineering of peptide nanomaterials, and exploitation of these materials to modulate cell responses. Expected outcomes include designed peptide nanostructures with specific chemical and physical cues to promote sustainable growth of desired cells, whilst inhibiting undesirable responses. These outcomes should provide benefits in terms of a practical toolkit for tailoring structure and function of peptide nanostructures and open up a new era in molecular design of smart biomaterials. This easily scalable, new materials platform will contribute to emerging high-value manufacturing industries in Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: Le170100148
Funder
Australian Research Council
Summary
An X-ray scattering facility for bulk and interfacial nanostructure. This project aims to establish an integrated, three-beamline facility for small- and wide-angle x-ray scattering (SWAXS) investigations of nanostructured materials in the bulk phase and at surfaces, focussed on soft and self-assembled materials such as polymers, biomaterials and molecular gels. This facility will act as a node for researchers in and around Sydney, providing research tools and training in small-angle scattering. ....An X-ray scattering facility for bulk and interfacial nanostructure. This project aims to establish an integrated, three-beamline facility for small- and wide-angle x-ray scattering (SWAXS) investigations of nanostructured materials in the bulk phase and at surfaces, focussed on soft and self-assembled materials such as polymers, biomaterials and molecular gels. This facility will act as a node for researchers in and around Sydney, providing research tools and training in small-angle scattering. It will provide cutting-edge research tools and advanced training in small-angle scattering. It is expected to yield important science in its own right, and enable researchers to more effectively use beamlines at Australian and international major research facilities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: Le100100096
Funder
Australian Research Council
Summary
A unique soft matter high-performance scanning probe microscopy (HP-SPM) facility. Soft matter research touches every aspect of our lives as it covers materials from the range of plastics found in cars, television sets and other mass-manufactured products, to new medical materials for tissue engineering and sensors. The proposed facility will enable Australia's leading scientists in this area to understand better how soft matter, including both biological and new advanced soft materials, behave ....A unique soft matter high-performance scanning probe microscopy (HP-SPM) facility. Soft matter research touches every aspect of our lives as it covers materials from the range of plastics found in cars, television sets and other mass-manufactured products, to new medical materials for tissue engineering and sensors. The proposed facility will enable Australia's leading scientists in this area to understand better how soft matter, including both biological and new advanced soft materials, behaves on the nano-scale level. This will put Australian researchers and engineers in a leading position for developing new treatments against cancer and other diseases, as well as harnessing the power of biology for application in areas such as waste treatment and energy production.Read moreRead less