Building advanced polymeric nanotubes for targeted drug delivery. Advanced drug delivery devices have major commercial applications in fighting diseases like cancer and infectious viruses. The success of this project will provide fundamental knowledge for the design of new drug delivery devices based on polymeric nanotubes. The project will also further advance Australia's nano- and bio-technological research and industries. This project will also provide additional benefit for developing contro ....Building advanced polymeric nanotubes for targeted drug delivery. Advanced drug delivery devices have major commercial applications in fighting diseases like cancer and infectious viruses. The success of this project will provide fundamental knowledge for the design of new drug delivery devices based on polymeric nanotubes. The project will also further advance Australia's nano- and bio-technological research and industries. This project will also provide additional benefit for developing controlled release systems in drug delivery and artificial vessels, and improve sensitivity in molecular sensors. The pioneering work proposed will ensure that Australia remains at the forefront of innovative scientific research within the rapidly advancing disciplines of nanotechnology and novel macromolecular design.Read moreRead less
Patterned assemblies of molecules on surfaces. Because of their redox and photophysical properties, artificial porphyrin systems have been designed for applications such as light-harvesting antennae, catalysts and sensors. Control of molecular orientation is required in order to construct practical devices, and in this project methods of assembling porphyrins on surfaces in well-defined patterns will be developed. Sophisticated methods will be used to characterise the films produced in these w ....Patterned assemblies of molecules on surfaces. Because of their redox and photophysical properties, artificial porphyrin systems have been designed for applications such as light-harvesting antennae, catalysts and sensors. Control of molecular orientation is required in order to construct practical devices, and in this project methods of assembling porphyrins on surfaces in well-defined patterns will be developed. Sophisticated methods will be used to characterise the films produced in these ways, in order to provide the information necessary to refine procedures and design new molecules suitable for advanced applications. Expected outcomes are new methods and architectures that can ultimately yield devices that act at the molecular level.Read moreRead less
New Strategies for Modelling Polyoxometalates. Polyoxometalates are a versatile class of genuine nanomaterials with remarkable chemical and physical properties and dimensions ranging from tens to tens of thousands of atoms. Designing functional materials which exploit their enormous potential is limited by practical difficulties in their structural characterization and restrictions on our ability to model their behaviour. In this project, we will develop a new strategy for computer modelling of ....New Strategies for Modelling Polyoxometalates. Polyoxometalates are a versatile class of genuine nanomaterials with remarkable chemical and physical properties and dimensions ranging from tens to tens of thousands of atoms. Designing functional materials which exploit their enormous potential is limited by practical difficulties in their structural characterization and restrictions on our ability to model their behaviour. In this project, we will develop a new strategy for computer modelling of polyoxometalates based on the classical molecular mechanics approach and high-level techniques. This novel line of attack will be exploited in the characterization of large and highly substituted derivatives which are key to developing functional materials.Read moreRead less