Discovery Early Career Researcher Award - Grant ID: DE230101231
Funder
Australian Research Council
Funding Amount
$390,295.00
Summary
The effect of nutrition on male life history traits in humans. This project will provide answers to fundamental questions in evolutionary biology while identifying diet compositions that will benefit human health and well-being. Using a longitudinal public-health database, the Raine Study, and a theoretical framework from the field of Nutritional Ecology, the project will provide new knowledge on how nutrition affects key life-history traits in humans including immune function, reproductive heal ....The effect of nutrition on male life history traits in humans. This project will provide answers to fundamental questions in evolutionary biology while identifying diet compositions that will benefit human health and well-being. Using a longitudinal public-health database, the Raine Study, and a theoretical framework from the field of Nutritional Ecology, the project will provide new knowledge on how nutrition affects key life-history traits in humans including immune function, reproductive health, physical appearance, and healthy ageing. A systematic literature review on how diet impacts these life-history traits in animals generally, and an experimental study of the effect of diet on health and reproduction in the house mouse (a lab analog species for humans) will complement the Raine Study findings.Read moreRead less
A Varied Diet, Ageing, and the Evolution of Life Histories. This research aims to understand how nutritional environments affect lifespan and its evolution. The expected outcomes are improved knowledge around the biology of ageing including the identification of diet-responsive genes and biological pathways. These elements will comprise targets for future applied studies on ageing, metabolic dysfunction and personalised nutrition. This study will also inform as to how lifespans evolve. Because l ....A Varied Diet, Ageing, and the Evolution of Life Histories. This research aims to understand how nutritional environments affect lifespan and its evolution. The expected outcomes are improved knowledge around the biology of ageing including the identification of diet-responsive genes and biological pathways. These elements will comprise targets for future applied studies on ageing, metabolic dysfunction and personalised nutrition. This study will also inform as to how lifespans evolve. Because lifespan is a fundamental demographic trait, this knowledge will improve ability to predict how populations adapt to environmental change. Lastly, through methodological innovation this project will also provide new statistical tools for studying how treatments affect the risk of death age specifically.Read moreRead less
Pathways to semelparity versus early maturity in animals and plants. The project aims to resolve an important but unresolved question in life history evolution and ecology- which mechanisms and constraints lead to semelparity (breeding once, which is rare), and which lead to fast life history (breeding early, which is common) in animals and plants. Theory predicts that both may be adaptations to schedules of adult death. Understanding why males and females have either semelparous or fast life hi ....Pathways to semelparity versus early maturity in animals and plants. The project aims to resolve an important but unresolved question in life history evolution and ecology- which mechanisms and constraints lead to semelparity (breeding once, which is rare), and which lead to fast life history (breeding early, which is common) in animals and plants. Theory predicts that both may be adaptations to schedules of adult death. Understanding why males and females have either semelparous or fast life history strategies is crucial to predicting survival of harvested and threatened species under pressure from climate change, drought, predators, and diseases that kill adults. Expected project outcomes include improved ability to address agents of decline of threatened animals and plants including semelparous species.Read moreRead less
Mitonuclear incompatibility, speciation, and the Z sex chromosome. This project will characterise the interaction between the mitochondrial and nuclear genome in several species and its contribution to the divergence of species. This interaction is at the heart of energy transformation and storage in all animals and its importance to evolution is yet to be fully understood. The research will provide insight into speciation processes by focusing on recent divergence in Australian finch species. W ....Mitonuclear incompatibility, speciation, and the Z sex chromosome. This project will characterise the interaction between the mitochondrial and nuclear genome in several species and its contribution to the divergence of species. This interaction is at the heart of energy transformation and storage in all animals and its importance to evolution is yet to be fully understood. The research will provide insight into speciation processes by focusing on recent divergence in Australian finch species. We will integrate genomics, bioenergetics, and whole organismal performance in growth, mobility and reproduction by studying birds in the wild and the laboratory. An overarching aim is to unite data from genomics, phenotype and physiology to understand the forces underlying the evolution of species, and biodiversityRead moreRead less
Hybridisation leading to lost sex: genomic and experimental insights. The project intends to apply advanced genomics to two classic Australian systems and quantitative genetics to one to address long-standing questions about why asexual reproduction is rare. It aims to test for rapid changes in genomes accompanying hybrid-origins of asexuals and whether this new diversity enables their ongoing evolution. The significance is that support for this hypothesis would challenge current theory for why ....Hybridisation leading to lost sex: genomic and experimental insights. The project intends to apply advanced genomics to two classic Australian systems and quantitative genetics to one to address long-standing questions about why asexual reproduction is rare. It aims to test for rapid changes in genomes accompanying hybrid-origins of asexuals and whether this new diversity enables their ongoing evolution. The significance is that support for this hypothesis would challenge current theory for why sex is so common. The expected outcome is to understand how variation is generated in natural populations with different ways of reproducing. Benefits would include significant contributions to global science, evolutionary training and potential applications in using hybridisation to manage threatened species or pests.Read moreRead less
Sex Differences in Trait Associations & Shapes: Analysis beyond Average. This project aims to identify and address current knowledge gaps in research on sex differences by employing different methodologies (bibliometrics, systematic mapping) and developing novel methods of meta-analysis. This project expects to generate a more holistic and complete view of sex differences than currently appreciated, by (meta-)analyzing the shapes of traits and associations between traits. Expected outcomes of th ....Sex Differences in Trait Associations & Shapes: Analysis beyond Average. This project aims to identify and address current knowledge gaps in research on sex differences by employing different methodologies (bibliometrics, systematic mapping) and developing novel methods of meta-analysis. This project expects to generate a more holistic and complete view of sex differences than currently appreciated, by (meta-)analyzing the shapes of traits and associations between traits. Expected outcomes of the project include taking the field of sex differences to the next level, and creating new and powerful meta-analytic methods, opening new avenues for research synthesis. This should provide significant benefits by directing future research in related fields and inspiring new kinds of (meta-)analyses across disciplines.Read moreRead less