Origin and evolution of animal-bacterial symbiosis. This project seeks to understand how interactions between animals and their microbial symbionts – the holobiont – evolved, and how they are influenced by the environment over an animal's life. Using a homegrown Australian model, a sea sponge from the Great Barrier Reef, and advanced multi-omic approaches (genomics plus cell biology), this project aims to uncover the mechanisms underlying the establishment and maintenance of the holobiont throug ....Origin and evolution of animal-bacterial symbiosis. This project seeks to understand how interactions between animals and their microbial symbionts – the holobiont – evolved, and how they are influenced by the environment over an animal's life. Using a homegrown Australian model, a sea sponge from the Great Barrier Reef, and advanced multi-omic approaches (genomics plus cell biology), this project aims to uncover the mechanisms underlying the establishment and maintenance of the holobiont through development, and under changing ecological and environmental conditions. Because of the evolutionary position of sponges, outcomes of this project expect to reveal cardinal rules governing animal-microbe interactions that are fundamental to the health and conservation of most animals and ecosystems.Read moreRead less
Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si a ....Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si alleviates stress in wheat, from gene to farm scale, providing cost-benefit analysis and a best–practice toolbox for implementation by farmers. Outcomes are anticipated to provide a cheaper and more environmentally sustainable solution to issues of water scarcity and yield losses to pests in Australia’s leading crop.Read moreRead less
Resolving the threat of ocean deoxygenation to coral resilience. This project aims to uncover the role low oxygen plays in shaping healthy corals over space and time. Climate change and land use development are rapidly deoxygenating shallow water coral reefs, yet we have no knowledge of how less oxygen availability affects critical life history factors that govern coral resilience: growth, reproduction, and stress tolerance. This project unites a multidisciplinary team of experts to, for the fir ....Resolving the threat of ocean deoxygenation to coral resilience. This project aims to uncover the role low oxygen plays in shaping healthy corals over space and time. Climate change and land use development are rapidly deoxygenating shallow water coral reefs, yet we have no knowledge of how less oxygen availability affects critical life history factors that govern coral resilience: growth, reproduction, and stress tolerance. This project unites a multidisciplinary team of experts to, for the first time, couple advanced oxygen sensing, metabolic physiology, coral reproductive and stress biology to transform our understanding of oxygen thresholds that are diagnostic of reduced coral competitive fitness across life stages (adults, juveniles, larvae), needed to improve coral reef ecosystem management.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101556
Funder
Australian Research Council
Funding Amount
$423,206.00
Summary
Investigating the responses of Australian native bees to climatic warming. This project aims to investigate changes to native bee cognition, morphology, and pollination capability in response to climatic warming. Using emerging experimental methods for behavioural testing and state-of-the-art 3D modelling of museum specimens, the project expects to identify which species are likely to experience change under future climate scenarios. This project expects to determine if increased temperatures ca ....Investigating the responses of Australian native bees to climatic warming. This project aims to investigate changes to native bee cognition, morphology, and pollination capability in response to climatic warming. Using emerging experimental methods for behavioural testing and state-of-the-art 3D modelling of museum specimens, the project expects to identify which species are likely to experience change under future climate scenarios. This project expects to determine if increased temperatures cause pollination deficits through impaired bee cognition and changed morphology. The knowledge gained in this project will allow us to identify vulnerable species and develop strategies across agriculture, government, and community sectors to support pollination and inform conservation priorities.Read moreRead less
Understanding mosquito smell system: a new frontier in mosquito control. This project aims to identify and functionally investigate mosquito smell receptors, which are critical in detecting volatile compounds and locating their hosts from a considerable distance away. Mosquitoes display preferences for certain hosts over others, primarily determined by volatile chemicals produced by hosts. This study builds on recently discovered, novel, host-derived volatile compounds, which can elicit robust r ....Understanding mosquito smell system: a new frontier in mosquito control. This project aims to identify and functionally investigate mosquito smell receptors, which are critical in detecting volatile compounds and locating their hosts from a considerable distance away. Mosquitoes display preferences for certain hosts over others, primarily determined by volatile chemicals produced by hosts. This study builds on recently discovered, novel, host-derived volatile compounds, which can elicit robust responses and attractiveness from mosquitoes. Expected outcomes of the project are enhanced understanding of mosquito smell system and behaviours. This could provide significant benefits to how we can fight mosquitoes and mosquito-transmitted diseases in a more efficient and environmentally responsible way.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100103
Funder
Australian Research Council
Funding Amount
$476,833.00
Summary
Improving efficacy of biopesticides through understanding mode of action. Insecticides are used extensively to control agricultural pests, but options are increasingly limited owing to environmental and human health concerns. A biopesticide, Bt, provides a valuable ‘soft’ option for control of caterpillars that are amongst the world's most damaging insect pests. However, little is known about how ingested Bt kills insects and this knowledge gap constrains options to improve efficacy and to count ....Improving efficacy of biopesticides through understanding mode of action. Insecticides are used extensively to control agricultural pests, but options are increasingly limited owing to environmental and human health concerns. A biopesticide, Bt, provides a valuable ‘soft’ option for control of caterpillars that are amongst the world's most damaging insect pests. However, little is known about how ingested Bt kills insects and this knowledge gap constrains options to improve efficacy and to counter resistance. This project connects industry end users (Cotton RDC; Bayer CropScience) with research training (Macquarie University) and applied research (CSIRO) to model how Bt interacts with the insect gut. This model will make valuable contributions to ensuring sustained and improved efficacy of Bt biopesticides.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100295
Funder
Australian Research Council
Funding Amount
$455,563.00
Summary
Unlocking the helminth ‘early infection gap’ using 3D cell culture models. This project aims to revolutionise the study of critical early host-parasite interactions using innovative 3D cell culture models, reducing our dependence on animal infections. Liver fluke is the most economically important zoonotic parasite of Australian livestock and is a significant contributor to global food insecurity. Due to the reliance of parasites on mammalian hosts to survive, very little is known about the earl ....Unlocking the helminth ‘early infection gap’ using 3D cell culture models. This project aims to revolutionise the study of critical early host-parasite interactions using innovative 3D cell culture models, reducing our dependence on animal infections. Liver fluke is the most economically important zoonotic parasite of Australian livestock and is a significant contributor to global food insecurity. Due to the reliance of parasites on mammalian hosts to survive, very little is known about the early infection process. Expected outcomes include new knowledge on key migratory stimuli and liver fluke biology. Benefits include the identification of drug targets and vaccine candidates for use in livestock via the development of animal-free in vitro screening platforms that will serve as a prototype for other parasites.Read moreRead less