Re-EValuating The Inhibition Of Stress Erosions (REVISE): Gastrointestinal Bleeding Prophylaxis In ICU
Funder
National Health and Medical Research Council
Funding Amount
$2,955,164.00
Summary
Around 50,000 patients in Australian Intensive Care Units receive a drug called pantoprazole each year with the aim of preventing bleeding from the gut. Recent research suggests this practice is ineffective and may harm patients by increasing their risk of serious infections. We will perform a definitive study to determine whether the widespread use of pantoprazole is beneficial or harmful.
A Cluster Randomised Controlled Trial Of Selective Decontamination Of The Digestive Tract In Critically Ill Patients
Funder
National Health and Medical Research Council
Funding Amount
$4,113,393.00
Summary
Sepsis is the most common cause of death in intensive care patients. Selective Decontamination of the Digestive Tract (SDD) is a treatment to reduce the risk of infection and improve survival for these patients. Many trials suggest SDD works but there has not been widespread uptake due to concerns that SDD will increase antibiotic resistance.rates. This trial will provide a definitive answer. If SDD reduces mortality without increasing antibiotic resistance, the study will have a global impact.
Rapidly giving intravenous fluid to prevent or treat shock (fluid resuscitation) is one of the commonest treatments given to critically ill patients. Current guidelines recommend crystalloid solutions but it is unknown whether any particular crystalloid is better than others. This trial will determine whether the use of one of two crystalloid fluids, saline or PlasmaLyte, reduces the risk of organ injuries, such as kidney failure, and improves patients chances of surviving critically illness.
Treatment Of Invasively Ventilated Adults With Early Activity And Mobilisation
Funder
National Health and Medical Research Council
Funding Amount
$1,467,137.00
Summary
The sickest patients in intensive care units (ICUs) receive prolonged, invasive support for their breathing. This is currently managed with complete bed rest, and results in severe muscle weakness, increased duration of hospital stay and poor recovery. We have found that early activity and mobilisation during invasive breathing support is safe and may improve survival and recovery. We will test early activity and mobilisation in a large randomised controlled trial of 750 ICU patients.
Coordination and communication in critical care: Assessing potential technology support. This project will examine temporal coordination demands of busy critical care environments, with the goal of developing better models and tools for evaluating the impact of information and communication technology (ICT) innovation. Millions of dollars can be wasted on healthcare ICT updates when the nature of critical care work, the means of communication, and temporal coordination demands are not fully unde ....Coordination and communication in critical care: Assessing potential technology support. This project will examine temporal coordination demands of busy critical care environments, with the goal of developing better models and tools for evaluating the impact of information and communication technology (ICT) innovation. Millions of dollars can be wasted on healthcare ICT updates when the nature of critical care work, the means of communication, and temporal coordination demands are not fully understood. The outcome of this project will be better conceptual and computational tools for assessing the impact of ICT innovation on safety-critical systems such as healthcare, so providing more cost-effective ICT solutions where there is rapidly-evolving ICT innovation.Read moreRead less
Developing a Model of ICU Transition Care; Enhancing Services, Enabling Nurses, Empowering Patients. The transition from the Intensive Care Unit (ICU) to the ward is traumatic for patients and families and difficult for ward nurses. Using focus groups and an intervention study, this research will develop and evaluate a model of ICU transition care and demonstrate the extent to which appropriate transition care improves a variety of outcomes for patients, families and staff. We anticipate that t ....Developing a Model of ICU Transition Care; Enhancing Services, Enabling Nurses, Empowering Patients. The transition from the Intensive Care Unit (ICU) to the ward is traumatic for patients and families and difficult for ward nurses. Using focus groups and an intervention study, this research will develop and evaluate a model of ICU transition care and demonstrate the extent to which appropriate transition care improves a variety of outcomes for patients, families and staff. We anticipate that this model will influence practice and policy decisions and be useful in other setting and with other groups who face life transitions such as the military, corrective care and rehabilitation.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120100402
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
The effectiveness of intervention in communication and safety climate in the operating room. This project will evaluate the effectiveness of an educational intervention on teamwork behaviours in surgery. It will deliver beneficial effects for communication in service delivery, safety and patient care in support of health care in high risk environments.