Portable instrument for quantification and genotyping of Cryptosporidium . Cryptosporidium is a parasitic protozoan, causing more than 48,000 deaths in children under 5 and 7.2 million disability-adjusted-life-years globally. A low-cost device that rapidly detects the parasite in drinking and recreational water is needed to enable effective disease management practices. Partnering with Advanced Universal Diagnotik, Seqwater, ALS Water and Gold Coast Water, this project aims to develop a novel de ....Portable instrument for quantification and genotyping of Cryptosporidium . Cryptosporidium is a parasitic protozoan, causing more than 48,000 deaths in children under 5 and 7.2 million disability-adjusted-life-years globally. A low-cost device that rapidly detects the parasite in drinking and recreational water is needed to enable effective disease management practices. Partnering with Advanced Universal Diagnotik, Seqwater, ALS Water and Gold Coast Water, this project aims to develop a novel device, comprising advanced microfluidics and biosensing technology for parasite quantification, genotyping and viability analysis. Expected outcomes are improved Cryptosporidium management, risk prediction, and rapid mitigation of impending outbreaks. The proposed platform has a great potential for detecting other pathogens.Read moreRead less
Milk protein profiling powered by multiplexed single molecule assay. This project aims to develop a novel device, comprising advanced single molecule imaging, microfluidics and immunoassay technologies, for quantification of milk protein variants. Milk quality is central to dairying and variants of proteins in milk affect its market value. No current milk protein detection technologies are readily applied in milk production quality control. This project aims to produce a device that can be used ....Milk protein profiling powered by multiplexed single molecule assay. This project aims to develop a novel device, comprising advanced single molecule imaging, microfluidics and immunoassay technologies, for quantification of milk protein variants. Milk quality is central to dairying and variants of proteins in milk affect its market value. No current milk protein detection technologies are readily applied in milk production quality control. This project aims to produce a device that can be used by milk producers and farms to profile protein variants with high sensitivity in a single test in an hour and screen unwanted protein contamination. The platform also has great potential for detecting other complex and low content analytes. It builds on innovations in nanoparticles and recent industry collaboration.Read moreRead less
Proteomic approaches for the detection of administered peptide hormones, growth factors and related substances in the horse. This project will develop innovative techniques for the detection of new protein doping agents potentially used within the Australian horse racing industry.
Bioinks for the 3D printing of cells made from off-the-shelf components. This project aims to develop a simple method for creating complex, multiple-cell-type three-dimensional (3D) cell cultures for in-vitro cell based assays. Using 3D printing technology, this project will develop a versatile polymer system, made from entirely commercially available components, that gels upon printing and has functionality to assist cells in adhering, growing and migrating. The 3D printing of multiple cell typ ....Bioinks for the 3D printing of cells made from off-the-shelf components. This project aims to develop a simple method for creating complex, multiple-cell-type three-dimensional (3D) cell cultures for in-vitro cell based assays. Using 3D printing technology, this project will develop a versatile polymer system, made from entirely commercially available components, that gels upon printing and has functionality to assist cells in adhering, growing and migrating. The 3D printing of multiple cell types will provide biological scientists with more realistic in-vitro cell assays to those found in-vivo. Applications of the research are in cell biology, studying diseases and developing new drugs.Read moreRead less
Electrochemical biosensors for detection of cardiac disease markers in blood. Cardiovascular diseases leading to heart failure have a prevalence of over 16 per cent in Australia. The social, economic and health burden is higher than for any other disease group. Hence, it is critically important to develop fit-for-purpose sensors of known cardiac biomarkers, which alert patients and clinicians of the risk of imminent heart failure.
Forensic platform technologies for roadside and workplace testing based on nanostructured silicon chips. Roadside drug testing has recently been incorporated into government legislation throughout Australia and abroad. The objective of this project is to develop advanced analysis technologies for implementing effective roadside and workplace testing. The availability of these technologies will increase the safety of Australian drivers and workers.