A data science framework for modelling disease patterns from medical images. A data science framework for modelling disease patterns from medical images. This project aims to extract models of disease patterns from medical imaging data, using deep learning, smart image processing, machine learning, and statistical modelling to quantify and model patterns conventional methods cannot detect. These disease models are expected to improve understanding of particular diseases and enable precision medi ....A data science framework for modelling disease patterns from medical images. A data science framework for modelling disease patterns from medical images. This project aims to extract models of disease patterns from medical imaging data, using deep learning, smart image processing, machine learning, and statistical modelling to quantify and model patterns conventional methods cannot detect. These disease models are expected to improve understanding of particular diseases and enable precision medicine, which recognises that there are important differences between individuals with a particular disease, and that when patients are separated into sub-populations with similar disease patterns, treatment can be tailored to these sub-populations.Read moreRead less
Automated pathogen detection using time-gated luminescence microscopy. A rapid and general means of in-situ pathogen identification would benefit the community by ensuring that appropriate treatments can be applied in the early stages of a disease. Patient prognosis is thereby improved and opportunities for multi-drug resistant organisms to arise are limited. Time-gated luminescence microscopy (TgM) exploits persistent luminescence to overcome autofluorescence, a serious problem in pathogen dete ....Automated pathogen detection using time-gated luminescence microscopy. A rapid and general means of in-situ pathogen identification would benefit the community by ensuring that appropriate treatments can be applied in the early stages of a disease. Patient prognosis is thereby improved and opportunities for multi-drug resistant organisms to arise are limited. Time-gated luminescence microscopy (TgM) exploits persistent luminescence to overcome autofluorescence, a serious problem in pathogen detection. Drug-resistant 'Golden Staph' (MRSA) will be used as the model organism to evaluate TgM efficacy. Ultimately however, TgM will be applied for the detection of tuberculosis, a highly contagious disease affecting the respiratory system of more than one-third of the world's population.Read moreRead less
High quality benthic and demersal surveys from small form factor underwater robots. This project will develop improved surveying systems for environmental consultancies. By enhancing the imaging and mapping capabilities of small underwater robots and extending automated interpretation tools to work with their data, this project will reduce operating costs, and increase the quality and quantity of scientifically useful data that they generate.
Novel Transmission Scanning and Computational Strategies for Quantitative microPET Imaging. Advances in detector technologies have led to the development and commercialisation of small animal imaging systems such as microPET which provide high resolution images of radioactive compounds in live animals, but the images can only be interpreted qualitatively. Our aim is to develop quantitative technologies for these new imaging systems. Major outcomes will include novel methods of measuring and corr ....Novel Transmission Scanning and Computational Strategies for Quantitative microPET Imaging. Advances in detector technologies have led to the development and commercialisation of small animal imaging systems such as microPET which provide high resolution images of radioactive compounds in live animals, but the images can only be interpreted qualitatively. Our aim is to develop quantitative technologies for these new imaging systems. Major outcomes will include novel methods of measuring and correcting for signal loss due to photon interactions in the body and integrated image reconstruction algorithms. This will lead to a new generation of quantitative imaging devices; the new technologies will be directly translatable to clinical imaging systems and will broaden the range of microPET applications in the life sciences.Read moreRead less
A theoretical framework for practical partial fingerprint identification. Fingerprints captured from a crime scene are often partial and poor quality which makes it difficult to identify the criminal suspects from large databases. This project will find mathematical models which can estimate the missing information located in the blank areas of a partial fingerprint and effectively identify it.
Multi-modal, Multi-dimensional Virtual Microscopy for Diagnostic Quantitative Pathology. This project will contribute to the development of a new generation of virtual microscopy (VM) systems that provide new and innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of pathology. These systems have the potential to significantly enhance the efficiency and efficacy of not only primary diagnostic workflows, but also aspects of profi ....Multi-modal, Multi-dimensional Virtual Microscopy for Diagnostic Quantitative Pathology. This project will contribute to the development of a new generation of virtual microscopy (VM) systems that provide new and innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of pathology. These systems have the potential to significantly enhance the efficiency and efficacy of not only primary diagnostic workflows, but also aspects of proficiency testing and continuing education vital for a vibrant, well regulated discipline. In addition, the project will contribute to our knowledge of the pathology assessed in the screening and diagnosis of cancers such as cervical, lung and bladder cancers.Read moreRead less
Omni-modality medical image analysis and visualisation. The term ‘Omni’-modality imaging (OMI) has been coined to describe the integration of multiple, complementary medical imaging modalities. However, there is currently a lack of an appropriate means to assimilate and derive maximum benefit from these integrated data. This project aims to provide a new approach to OMI data analysis and visualisation, by deriving a novel ‘level of relevance’ from the overlapping anatomical and pathological stru ....Omni-modality medical image analysis and visualisation. The term ‘Omni’-modality imaging (OMI) has been coined to describe the integration of multiple, complementary medical imaging modalities. However, there is currently a lack of an appropriate means to assimilate and derive maximum benefit from these integrated data. This project aims to provide a new approach to OMI data analysis and visualisation, by deriving a novel ‘level of relevance’ from the overlapping anatomical and pathological structures in the data which will be used to suppress superfluous data and highlight the most relevant data to maximise the information gained from the OMI data. Further, OMI visualisation is proposed to efficiently navigate through the overlapping data.Read moreRead less
Vision Model Based Perceptual Digital Video Coding. Digital video coding and compression is an enabling technology and has diversified applications in audiovisual communications, multimedia computing, digital television broadcast and electronic entertainment industries. The project aims at spearheading research in theory, techniques and implementation of perceptual video coding in order to achieve constant and guaranteed quality in visual communications and services. It will explore a new appr ....Vision Model Based Perceptual Digital Video Coding. Digital video coding and compression is an enabling technology and has diversified applications in audiovisual communications, multimedia computing, digital television broadcast and electronic entertainment industries. The project aims at spearheading research in theory, techniques and implementation of perceptual video coding in order to achieve constant and guaranteed quality in visual communications and services. It will explore a new approach to digital video coding other than the constant bit rate coding techniques which have dominated digital video research for the past four decades. It will form a part of the theoretical foundation and principles for the next generation video coding and compression techniques, and may lead to new standards and practice.Read moreRead less
Data Management Technologies for the Magnetic Resonance Imaging e-Research Grid. Howard Florey Institute researchers will collaborate with SGI's file-systems engineering team. Substantial benefits are expected from the development of techniques to support centralized and distributed processing medical image datasets. Issues requiring research include file space allocation algorithms and caching strategies. The proposed rapid database access technologies aim at solving these problems in the medic ....Data Management Technologies for the Magnetic Resonance Imaging e-Research Grid. Howard Florey Institute researchers will collaborate with SGI's file-systems engineering team. Substantial benefits are expected from the development of techniques to support centralized and distributed processing medical image datasets. Issues requiring research include file space allocation algorithms and caching strategies. The proposed rapid database access technologies aim at solving these problems in the medical imaging research context. The project attempts to 'improve data management for existing and new business applications'. This enhanced sharing of information will improve critical mass therefore fostering national and international collaboration. Read moreRead less
Semantic Authentication of Visual Data. Data authentication systems can detect the smallest modification to a message. Authentication systems for media objects such as images, and audio and video clips have a different requirement they must ensure authenticity of the content without needing all the changes to be detectable. The aims of this project are to develop a framework for design and analysis of image and video authentication systems, and construct secure and flexible systems that can be ....Semantic Authentication of Visual Data. Data authentication systems can detect the smallest modification to a message. Authentication systems for media objects such as images, and audio and video clips have a different requirement they must ensure authenticity of the content without needing all the changes to be detectable. The aims of this project are to develop a framework for design and analysis of image and video authentication systems, and construct secure and flexible systems that can be used in practice. This research addresses the urgent need of providing security for multimedia objects in electronic commerce and is of high importance to the acceptance of advanced communication and information services.Read moreRead less