Threats of avian pathogens to endangered parrots and human health: developing and utilizing tools for risk reduction. Emerging infectious diseases (EID) are among the most significant threats to conservation, agriculture and public health worldwide. Among these are two globally significant avian pathogens, Chlamydia psittaci and Beak and Feather Disease Virus. This project aims to determine transmission dynamics, fitness costs of infection, and quantify the roles of genetic diversity and host st ....Threats of avian pathogens to endangered parrots and human health: developing and utilizing tools for risk reduction. Emerging infectious diseases (EID) are among the most significant threats to conservation, agriculture and public health worldwide. Among these are two globally significant avian pathogens, Chlamydia psittaci and Beak and Feather Disease Virus. This project aims to determine transmission dynamics, fitness costs of infection, and quantify the roles of genetic diversity and host stress in infection and disease emergence. The project aims to also determine to what extent zoonotic poultry/human infection is related to infection in wild birds. The outcomes aim to be the development of critical knowledge and tools to help manage two avian pathogens causing significant conservation, agricultural and public health concern around the world.Read moreRead less
Coevolution of sundew bugs and sundews. This project aims to conduct a study of insect-plant interactions to determine if insects and plants coevolve or if they diversify by other evolutionary processes. Insect-plant coevolution is a hotly contested field in evolutionary biology. In Australia, a remarkable interaction exists between carnivorous plants and a group of bugs that steal the plant’s prey. This system offers a great opportunity to test competing coevolutionary theories through a combin ....Coevolution of sundew bugs and sundews. This project aims to conduct a study of insect-plant interactions to determine if insects and plants coevolve or if they diversify by other evolutionary processes. Insect-plant coevolution is a hotly contested field in evolutionary biology. In Australia, a remarkable interaction exists between carnivorous plants and a group of bugs that steal the plant’s prey. This system offers a great opportunity to test competing coevolutionary theories through a combination of historical and ecological approaches. The project expects to showcase the evolution and uniqueness of Australia’s native biota.Read moreRead less
An interdisciplinary approach to host-pathogen interactions in infection. This project aims to understand the molecular and cellular interactions between host and parasite, as well as providing a quantitative framework for analysing infection dynamics in other systems. Infection involves a complex interaction between the host and the parasite, which is very dynamic and therefore difficult to study by traditional sampling and analysis approaches. This project has combined mathematical modelling w ....An interdisciplinary approach to host-pathogen interactions in infection. This project aims to understand the molecular and cellular interactions between host and parasite, as well as providing a quantitative framework for analysing infection dynamics in other systems. Infection involves a complex interaction between the host and the parasite, which is very dynamic and therefore difficult to study by traditional sampling and analysis approaches. This project has combined mathematical modelling with a novel experimental protocol to allow the study of kinetics of parasite replication in vivo. Expected outcomes will provide significant benefits, such as new avenues for vaccination and immune intervention.Read moreRead less
Sugar transporters in coral symbiosis and origin of parasitism. We aim to identify how symbiotic algae feed sugar to their coral hosts. Corals need this algal sugar to exist, but no one knows how it is transferred, so understanding this crucial mechanism is hugely significant. The first benefit of this research will be a fundamental understanding about how two organisms (algae and coral) cooperate to build habitats like the Great Barrier Reef. We also aim to explore whether coral/algal coopera ....Sugar transporters in coral symbiosis and origin of parasitism. We aim to identify how symbiotic algae feed sugar to their coral hosts. Corals need this algal sugar to exist, but no one knows how it is transferred, so understanding this crucial mechanism is hugely significant. The first benefit of this research will be a fundamental understanding about how two organisms (algae and coral) cooperate to build habitats like the Great Barrier Reef. We also aim to explore whether coral/algal cooperation paved the way for the origin of parasitism. The second key outcome will be to identify the precise molecular mechanism that allowed parasitism to arise. This will benefit us through understanding the origins of important diseases such as human malaria and related infections of livestock and wildlife.
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Discovery Early Career Researcher Award - Grant ID: DE200100977
Funder
Australian Research Council
Funding Amount
$419,016.00
Summary
How ecology shapes the viromes of wild birds. This project will reveal the host factors associated with the diversity, evolution and dynamics of viruses using state-of-the-art metatranscriptomics in Australian wild birds. The structure of virus communities and their associated ecological drivers in wild animal hosts remain a black-box, even though they are the largest source of viral diversity in nature. This project expects to generate key insights into host-associated drivers of viral communit ....How ecology shapes the viromes of wild birds. This project will reveal the host factors associated with the diversity, evolution and dynamics of viruses using state-of-the-art metatranscriptomics in Australian wild birds. The structure of virus communities and their associated ecological drivers in wild animal hosts remain a black-box, even though they are the largest source of viral diversity in nature. This project expects to generate key insights into host-associated drivers of viral community dynamics and the subsequent effect of anthropogenic factors such as urbanisation and poultry production. Identifying host factors that affect viral ecology in wild birds will constitute a cornerstone in understanding the emergence of virulent viruses and/or their spread to poultry or humansRead moreRead less