Genomic signatures of adaptive diversification in woodland Eucalyptus. This project aims to map the sources of adaptive alleles underlying diversification is to reveal insights into the mechanisms of speciation. The source of the raw material for evolution can have significant impacts on the speed with which populations can adapt. An emerging pattern in speciation research is the importance of ancient alleles and introgressed genes, which differ in the genomic signatures left by selection. Eucal ....Genomic signatures of adaptive diversification in woodland Eucalyptus. This project aims to map the sources of adaptive alleles underlying diversification is to reveal insights into the mechanisms of speciation. The source of the raw material for evolution can have significant impacts on the speed with which populations can adapt. An emerging pattern in speciation research is the importance of ancient alleles and introgressed genes, which differ in the genomic signatures left by selection. Eucalyptus offers a unique opportunity to explore these modes of evolution using the latest genomic tools. Improving our understanding of adaptation and genetic variation in woodland eucalypts is expected to make a significant contribution to their conservation, management and restoration.Read moreRead less
Genome-wide discovery of translation control mechanisms. This project aims to reveal currently unknown molecular details of protein synthesis, a step of gene expression that is central to all of life. To achieve this, innovative methods based on next-generation sequencing will be deployed in the yeast model organism. Yeasts are of importance as pathogens as well as in the food and biotechnology industry sector. Thus, new knowledge generated in this project will help solve problems of invasive pa ....Genome-wide discovery of translation control mechanisms. This project aims to reveal currently unknown molecular details of protein synthesis, a step of gene expression that is central to all of life. To achieve this, innovative methods based on next-generation sequencing will be deployed in the yeast model organism. Yeasts are of importance as pathogens as well as in the food and biotechnology industry sector. Thus, new knowledge generated in this project will help solve problems of invasive pathogenic behaviour and biomass production.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101206
Funder
Australian Research Council
Funding Amount
$372,536.00
Summary
Beyond genes: How the extended genotype of plants facilitates adaptation. Adaptation to environmental change is required for species to persist, however rapid environmental change may exceed the limits of traditional genetic adaptation leading to widespread decline. Recent work has highlighted the 'extended genotype' as an additional factor influencing adaptive phenotypes. This project aims to examine DNA methylation and polyploidisation as both a cause and consequence of the adaptation process ....Beyond genes: How the extended genotype of plants facilitates adaptation. Adaptation to environmental change is required for species to persist, however rapid environmental change may exceed the limits of traditional genetic adaptation leading to widespread decline. Recent work has highlighted the 'extended genotype' as an additional factor influencing adaptive phenotypes. This project aims to examine DNA methylation and polyploidisation as both a cause and consequence of the adaptation process using natural populations of the model cereal Brachypodium distachyon. The project aims to determine the architecture of these features and how their variability impacts adaptive traits such as flowering time. From the functional role of the extended genotype the project endeavours to predict and select genetic responses to the environment.Read moreRead less
Improving access to phylogenomic resources for under-resourced species: a new look at existing tools. This project will have an impact on our understanding of how to most effectively use existing genomic resources to benefit a wider range of species and to better design new genomic resources. By doing so, improved access to genomic resources will be provided to species that currently have few options.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100143
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
Flexible architecture high-performance computing facility for the intersect consortium of New South Wales. This new supercomputing facility is an important addition to the nation's research infrastructure and will enable world-leading, New South Wales researchers to continue their ground breaking work in increasingly competitive environments. Much of the research to be undertaken at the facility lies in areas of national priority, including frontier technologies and environmental sustainability.
Discovery Early Career Researcher Award - Grant ID: DE160100685
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Historical pest genomes inform debate about how rapid evolution proceeds. This project plans to compare the genomes of archived and contemporary specimens to discover how two key Australian pest moths have adapted to insecticides, aiding prediction of how they may respond in the future. Agricultural pest species are often capable of rapid adaptation to insecticides, resulting in widespread genetic resistance. Does this resistance build on existing genetic variation, or are fresh mutations used t ....Historical pest genomes inform debate about how rapid evolution proceeds. This project plans to compare the genomes of archived and contemporary specimens to discover how two key Australian pest moths have adapted to insecticides, aiding prediction of how they may respond in the future. Agricultural pest species are often capable of rapid adaptation to insecticides, resulting in widespread genetic resistance. Does this resistance build on existing genetic variation, or are fresh mutations used to produce a fast adaptive response? How do adaptive strategies differ among key Australian pests? This project aims to answer these questions and advance understanding of mechanisms that underpin rapid evolution to improve approaches toward pest management and agricultural protection.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100002
Funder
Australian Research Council
Funding Amount
$1,040,000.00
Summary
Distributed Memory Cluster for the Intersect consortium of universities. Distributed memory cluster:
This project aims to establish a new supercomputing facility. The NSW research community has used high performance computing (HPC) to achieve major breakthroughs across a diverse range of disciplines including astrophysics, bioinformatics, environmental science, information technology and engineering. As the use of HPC increases, the application-specific needs of the research community become mo ....Distributed Memory Cluster for the Intersect consortium of universities. Distributed memory cluster:
This project aims to establish a new supercomputing facility. The NSW research community has used high performance computing (HPC) to achieve major breakthroughs across a diverse range of disciplines including astrophysics, bioinformatics, environmental science, information technology and engineering. As the use of HPC increases, the application-specific needs of the research community become more diverse, requiring greater flexibility as well as higher performance. The present facility is no longer internationally competitive, and is hampering progress in cutting edge research. The new cluster is designed to provide a greater than 10-fold increase in computing capability.Read moreRead less
TraitCapture: Genomic modelling for plant phenomics under environmental stress. This project aims to develop software to integrate new hyper-spectral and 3D growth models of plant phenomics with population genomics to identify heritable developmental traits across varied environments. Genome wide association studies aim to then be used to identify causal genes. Functional structural plant models incorporating genetic variation will be used to predict growth under simulated stress environments. ....TraitCapture: Genomic modelling for plant phenomics under environmental stress. This project aims to develop software to integrate new hyper-spectral and 3D growth models of plant phenomics with population genomics to identify heritable developmental traits across varied environments. Genome wide association studies aim to then be used to identify causal genes. Functional structural plant models incorporating genetic variation will be used to predict growth under simulated stress environments. The research team unites international industry, the Australian Plant Phenomics Facility, and university statistical geneticists. TraitCapture software will use open standards applicable to both controlled and field environments enabling plant breeders to pre-select adaptive traits to increase crop productivity under environmental stress.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100443
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Landscape genomics to make an endangered community resilient. This project aims to use landscape genomic techniques to assess how key species of the critically endangered Box-Gum Grassy Woodland community migrate and adapt under changing environmental conditions. Changing climate and land use threaten ecological communities, and alter environments at alarming rates. When species are pushed beyond their environmental tolerances, they will migrate, adapt or face local extinction. This alteration o ....Landscape genomics to make an endangered community resilient. This project aims to use landscape genomic techniques to assess how key species of the critically endangered Box-Gum Grassy Woodland community migrate and adapt under changing environmental conditions. Changing climate and land use threaten ecological communities, and alter environments at alarming rates. When species are pushed beyond their environmental tolerances, they will migrate, adapt or face local extinction. This alteration of the community structure affects the stability and function of the ecosystem. Expected outcomes include efficient use of limited conservation resources, ensuring the long term persistence of the endangered community.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100151
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Enhancing resistance to wheat stripe rust disease. This project aims to investigate why wheat succumbs to stripe rust fungus, a grave threat to global wheat production. Wheat is the primary agricultural and revenue crop of Australia, cultivated since early European settlement. Severe disease epidemics arise when the fast evolving rust pathogen breaks down host plant genetic resistance. This project will investigate the molecular mechanisms of host-pathogen recognition and the consequences of pat ....Enhancing resistance to wheat stripe rust disease. This project aims to investigate why wheat succumbs to stripe rust fungus, a grave threat to global wheat production. Wheat is the primary agricultural and revenue crop of Australia, cultivated since early European settlement. Severe disease epidemics arise when the fast evolving rust pathogen breaks down host plant genetic resistance. This project will investigate the molecular mechanisms of host-pathogen recognition and the consequences of pathogen variation to determine the causes of resistance breakdown. The expected outcome is robust rust-resistant wheat cultivars to maintain global food security.Read moreRead less